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EDTA chelation, high-dose vitamins/minerals may provide additional benefit for MI patients

Heart attack patients given a combination of high-dose oral vitamins and minerals do not exhibit a significant reduction in recurrent cardiac events, according to research presented today at the American College of Cardiology's 62nd Annual Scientific Session.

13 Mar 2013

Trial evaluates ranolazine in patients with diabetes, coronary artery disease and angina

A commonly used anti-anginal drug reduces chest pain in patients with type 2 diabetes and appears to have a more pronounced effect in those with poorer glucose control, according to research presented today at the American College of Cardiology's 62nd Annual Scientific Session.

13 Mar 2013

Researchers work on stem cell treatments to halt vision loss caused by diabetic retinopathy

Researchers at the Eugene and Marilyn Glick Eye Institute and the Indiana Center for Vascular Biology at Indiana University School of Medicine are on the cusp of perfecting stem cell treatments that would halt - and potentially reverse - vision loss caused by diabetic retinopathy.

13 Mar 2013

Catheter-delivered aortic valve durable at three years

All-cause and cardiovascular mortality were similar for transaortic valve replacement compared to open-heart surgery in high-risk older patients at three years with no increased risk of stroke after 30 days, according to results from the PARTNER study presented today at the American College of Cardiology's 62nd Annual Scientific Session.

13 Mar 2013

Burnt-out employees have increased risk of heart disease, researcher finds

Americans work longer hours, take fewer vacation days, and retire later than employees in other industrialized countries around the globe.

13 Mar 2013

RELAX study finds no beneficial effects of erectile dysfunction drug for diastolic heart failure

Despite high expectations for a commonly used erectile dysfunction drug to treat patients with diastolic heart failure, no beneficial effects were found in a study presented today at the American College of Cardiology's 62nd Annual Scientific Session.

13 Mar 2013

Swine study shows that moderate exercise can affect ovarian cells

A short walk around the barn might improve the future fertility of Yorkshire gilts. According to research presented by Samantha Kaminski, a graduate student at North Dakota State University, swine fetuses showed significant ovarian development after their mothers exercised.

13 Mar 2013

Research: Digoxin reduces hospital admission of older, acute heart failure patients

Digoxin significantly reduces the likelihood of hospital admission due to all causes among ambulatory older patients with chronic heart failure and reduced ejection fraction, according to research presented today at the American College of Cardiology's 62nd Annual Scientific Session.

13 Mar 2013

Adult stem cell treatment for diabetic wounds

Pre-clinical research has generated some very promising findings using adult stem cells for the treatment of diabetic wounds. The research carried out by scientists at the National University of Ireland Galway, is published in Diabetes, the official journal of the American Diabetes Association.

13 Mar 2013

Researchers develop new plug-and-play method to assemble complex cell microenvironments

Researchers at Columbia Engineering have developed a new "plug-and-play" method to assemble complex cell microenvironments that is a scalable, highly precise way to fabricate tissues with any spatial organization or interest—such as those found in the heart or skeleton or vasculature.

12 Mar 2013

Targeting Mer receptors sensitize AML and ALL to chemotherapies

Two University of Colorado Cancer Center studies show that the protein receptor Mer is overexpressed in many leukemias, and that inhibition of this Mer receptor results in the death of leukemia cells - without affecting surrounding, healthy cells.

12 Mar 2013

Cangrelor solidly outperforms clopidogrel during percutaneous coronary intervention

The experimental anti-clotting drug cangrelor solidly outperformed commonly used clopidogrel in a large global trial of patients who underwent coronary stent procedures, according to data from the phase III CHAMPION PHOENIX study presented today at the American College of Cardiology's 62nd Annual Scientific Session.

12 Mar 2013

Women with atrial fibrilation have more symptoms and lower quality of life than men

Women with atrial fibrilation have more symptoms and lower quality of life than men with the same heart condition, according to an analysis of patients in a large national registry compiled by the Duke Clinical Research Institute.

12 Mar 2013

Cangrelor more effective than clopidogrel in preventing blood clots

A new and experimental anti-clotting drug, cangrelor, proved better than the commonly used clopidogrel and was significantly more effective at preventing blood clots in a large trial of patients who underwent coronary stent procedures.

12 Mar 2013

Study: On-site surgery services unnecessary for patient safety in non-emergency angioplasty

Non-emergency angioplasty performed at hospitals without on-site cardiac surgery capability is no less safe and effective than angioplasty performed at hospitals with cardiac surgery services, according to research presented today at the American College of Cardiology's 62nd Annual Scientific Session.

12 Mar 2013

Aliskiren and standard therapy not associated with reduced CV death or HF rehospitalization

Among patients hospitalized for heart failure (HF) with reduced left ventricular ejection fraction (LVEF; a measure of how well the left ventricle of the heart pumps with each contraction), initiation of the medication aliskiren in addition to standard therapy did not reduce cardiovascular death or HF rehospitalization at 6 or 12 months after discharge, according to a study published online by JAMA.

12 Mar 2013

Darapladib can significantly reduce leaks in the blood brain barrier

A research team led by Robert Nagele, PhD, of the New Jersey Institute for Successful Aging (NJISA) at the University of Medicine and Dentistry of New Jersey (UMDNJ)-School of Osteopathic Medicine, has demonstrated that the anti-atherosclerosis drug darapladib can significantly reduce leaks in the blood brain barrier.

12 Mar 2013

Study links prenatal DDT exposure to hypertension in adults

Infant girls exposed to high levels of the pesticide DDT while still inside the womb are three times more likely to develop hypertension when they become adults, according to a new study led by the University of California, Davis.

12 Mar 2013

Mir-125a-5p plays an essential role in ensuring that embryonic tissue segments form properly

New research shows that a tiny piece of RNA has an essential role in ensuring that embryonic tissue segments form properly.

12 Mar 2013

ECMO and mechanical CPR use can lead to unexpected survival in severe heart attack patients

The use of extracorporeal membrane oxygenation (ECMO), accompanied by mechanical CPR, in patients with massive myocardial infarctions can lead to unexpected survival. These study findings are being presented March 9 at the American College of Cardiology Scientific Sessions.

12 Mar 2013

Blood News and Research

EDTA chelation, high-dose vitamins/minerals may provide additional benefit for MI patients

Trial evaluates ranolazine in patients with diabetes, coronary artery disease and angina

Researchers work on stem cell treatments to halt vision loss caused by diabetic retinopathy

Catheter-delivered aortic valve durable at three years

Burnt-out employees have increased risk of heart disease, researcher finds

RELAX study finds no beneficial effects of erectile dysfunction drug for diastolic heart failure

Swine study shows that moderate exercise can affect ovarian cells

Research: Digoxin reduces hospital admission of older, acute heart failure patients

Adult stem cell treatment for diabetic wounds

Researchers develop new plug-and-play method to assemble complex cell microenvironments

Targeting Mer receptors sensitize AML and ALL to chemotherapies

Cangrelor solidly outperforms clopidogrel during percutaneous coronary intervention

Women with atrial fibrilation have more symptoms and lower quality of life than men

Cangrelor more effective than clopidogrel in preventing blood clots

Study: On-site surgery services unnecessary for patient safety in non-emergency angioplasty

Aliskiren and standard therapy not associated with reduced CV death or HF rehospitalization

Darapladib can significantly reduce leaks in the blood brain barrier

Study links prenatal DDT exposure to hypertension in adults

Mir-125a-5p plays an essential role in ensuring that embryonic tissue segments form properly

ECMO and mechanical CPR use can lead to unexpected survival in severe heart attack patients

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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