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Abbott announces data from MitraClip system study on mitral regurgitation

Abbott today announced data from the EVEREST II (Endovascular Valve Edge-to-Edge REpair STudy) High Surgical Risk cohort evaluating the company's first-in-class catheter-based MitraClip System for the treatment of mitral regurgitation (MR).

11 Mar 2013

Cardiovascular disease risk in women higher than you think

In conjunction with International Women's Day, the European Cardiology Society reminds women that they may be at a greater risk for cardiovascular disease (CVD) than they think.

8 Mar 2013

Investigational treatment for ulcerative colitis (UC) and Crohn’s disease (CD) has Marketing Authorisation Application submitted

Takeda Pharmaceutical Company Limited (“Takeda”) today announced that a Marketing Authorisation Application (MAA) has been submitted to The European Medicines Agency (EMA) for vedolizumab, an investigational, gut-selective humanized monoclonal antibody for the treatment of adults with moderately to severely active ulcerative colitis (UC) and Crohn’s disease (CD), the two most common types of inflammatory bowel disease (IBD).

8 Mar 2013

Inflammatory marker for schizophrenia treatment resistance, severity

Levels of the inflammatory marker soluble tumor necrosis factor receptor 1 may be associated with severity of symptoms and treatment resistance in schizophrenia, say Brazilian scientists.

8 Mar 2013

Pharmacist-led intervention combats hypertension

A home-based intervention led by clinical pharmacists and involving an internet monitoring tool results in marked reductions in blood pressure, say researchers.

8 Mar 2013

Weill Cornell receives NIMH grant to discover novel biomarkers for chronic fatigue syndrome

Weill Cornell Medical College has been awarded more than $1.9 million by the National Institute of Mental Health of the National Institutes of Health to lead an innovative research study using advanced neuroimaging and clinical evaluations of patients with chronic fatigue syndrome (CFS).

8 Mar 2013

Cardiac rehab program may reduce death rate in women with coronary artery disease

Women with coronary artery disease who completed a 12-week cardiac rehabilitation program were two-thirds less likely to die compared to those who were not referred to the program.

8 Mar 2013

Chronic obstructive pulmonary disease (COPD) inflammatory subtypes: an interview with Dr Vanessa McDonald, University of Newcastle, Australia

COPD is defined as a preventable and treatable disease associated with significant extrapulmonary consequences that may contribute to severity. The pulmonary component of COPD is characterised by airflow limitation that is not fully reversible. The airflow limitation is usually progressive with an abnormal inflammatory response of the lungs to noxious particles (GOLD Strategy Document). Airflow obstruction in COPD is not highly variable and largely irreversible.

8 Mar 2013

Patients with PTSD more likely to develop insulin resistance, metabolic syndrome and heart disease

Patients diagnosed with post-traumatic stress disorder (PTSD) have a significantly higher risk of developing insulin resistance and metabolic syndrome, placing them at greater risk for heart disease and diabetes, according to research being presented at the American College of Cardiology's 62nd Annual Scientific Session. Researchers say public health interventions are urgently needed to prevent PTSD-related metabolic disorder at its early, reversible stage.

8 Mar 2013

Jersey Shore’s Bariatric Surgery Program helps obese people to lose weight

For the obese community, the benefits of weight-loss surgery go beyond what the eye can see. Jersey Shore University Medical Center's Bariatric Surgery Program offers the education and tools necessary for people to make the life changing decision of losing weight.

8 Mar 2013

APIC offers tips to stay infection-free

Beyond the obvious—steering clear of runny noses and hacking coughs—the Association for Professionals in Infection Control and Epidemiology (APIC) presents some other practical ways of staying infection-free.

8 Mar 2013

Telemedicine use appears to help urban communities achieve blood pressure goals

Using a telemedicine system to engage people in underserved, urban communities to measure and report their blood pressure remotely-outside of the doctor's office-appears to help them achieve blood pressure goals and improve adherence to lifestyle changes and medication recommendations, according to research being presented at the American College of Cardiology's 62nd Annual Scientific Session.

8 Mar 2013

Being overweight from young age can lead to heavier hearts later in life

Being overweight, especially from a young age, appears to lead to a bigger heart later in life, a condition that has been linked to serious heart problems and even death, according to research being presented at the American College of Cardiology's 62nd Annual Scientific Session.

8 Mar 2013

Upheaval caused by Hurricane Katrina seems to have disrupted heart attack timing

The upheaval caused by Hurricane Katrina seems to have disrupted the usual timing of heart attacks, shifting peak frequency from weekday mornings to weekend nights, in a change in pattern that persisted a full five years after the storm, according to research being presented at the American College of Cardiology's 62nd Annual Scientific Session.

8 Mar 2013

Study shows reduction of brain capillaries in mice immunized with amyloid beta

University of British Columbia researchers have successfully normalized the production of blood vessels in the brain of mice with Alzheimer's disease (AD) by immunizing them with amyloid beta, a protein widely associated with the disease.

8 Mar 2013

African-American women with breast cancer more likely to develop heart failure

African-American women who survive breast cancer are more likely to develop heart failure than other women who have beaten the disease, according to research being presented at the American College of Cardiology's 62nd Annual Scientific Session.

8 Mar 2013

Minor weight loss may increase risk of cardiac events among patients implanted with CRT-D

Even minor weight loss is associated with worse health outcomes among patients implanted with a certain type of defibrillator known as cardiac resynchronization therapy with defibrillator (CRT-D), according to research being presented at the American College of Cardiology's 62nd Annual Scientific Session.

8 Mar 2013

Melittin-loaded nanoparticles can destroy human immunodeficiency virus

Nanoparticles carrying a toxin found in bee venom can destroy human immunodeficiency virus (HIV) while leaving surrounding cells unharmed, researchers at Washington University School of Medicine in St. Louis have shown.

8 Mar 2013

Acceleron commences ACE-536 phase 2 study in beta-thalassemia

Acceleron Pharma, Inc., a biopharmaceutical company developing protein therapeutics for cancer and orphan diseases, today announced the initiation of a phase 2 study of its novel, investigational protein therapeutic, ACE-536, to treat patients with beta-thalassemia, a genetic hematologic disorder causing chronic and life-threatening anemia and serious complications affecting the spleen, liver and heart.

7 Mar 2013

Tranexamic acid role in coronary bypass surgery

Tranexamic acid balances the increased bleeding risk associated with recent clopidogrel use in patients undergoing on-pump coronary artery bypass grafting, shows a randomized trial.

7 Mar 2013