Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Stem cells make bone marrow cancer resistant to treatment

Scientists at the Johns Hopkins Kimmel Cancer Center say they have evidence that cancer stem cells for multiple myeloma share many properties with normal stem cells and have multiple ways of resisting chemotherapy and other treatments.

15 Jan 2008

Scientists identify cells that promote formation of lethal lung metastases

Cancer patients usually ask what can be done after a primary tumor has already spread, or metastasized, to other organs.

11 Jan 2008

New way to boost red blood cell numbers

A common treatment for anemia a deficiency in red blood cells (rbcs) caused by their insufficient production, excessive destruction, or excessive loss is administration of recombinant erythropoietin (Epo), a hormone that stimulates the production of rbc precursors by the bone marrow.

11 Jan 2008

Wisconsin now screens all newborns for severe combined immune deficiency

Wisconsin became the first state in the nation to screen all newborns for Severe Combined Immune Deficiency (SCID).

4 Jan 2008

FDA reviews new data on risks of erythropoiesis-stimulating agents

The U.S. Food and Drug Administration (FDA) is reviewing new data from two studies that provide further evidence of the risks of anemia drugs known as erythropoiesis-stimulating agents, or ESAs.

4 Jan 2008

Cardiac stem cell therapy research

Since the year 2000, much has been learned about the potential for using transplanted cells in therapeutic efforts to treat varieties of cardiac disorders.

28 Dec 2007

Researchers train the immune system to deliver virus that destroys cancer in lab models

An international team of researchers led by Mayo Clinic have designed a technique that uses the body's own cells and a virus to destroy cancer cells that spread from primary tumors to other parts of the body through the lymphatic system.

20 Dec 2007

New treatment option offers hope to multiple myeloma patients

Patients diagnosed with multiple myeloma, an often deadly bone marrow cancer, rarely live more than three years after diagnosis if treated with conventional chemotherapy or even some of the newer drug therapies.

20 Dec 2007

Boy in a bubble gets leukaemia after gene therapy

A child who was born with a rare immunodeficient condition has developed leukaemia as a result of gene therapy he received at Great Ormond Street children's hospital in London.

19 Dec 2007

High-dose chemo and stem cell transplant shows little or no survival benefit for breast cancer

High-dose chemotherapy and autologous stem cell transplantation, the controversial, arduous, yet once-popular combination treatment that fell out of favor as a therapy for breast cancer, has proven not to be beneficial as an adjuvant therapy for women with node-positive disease, according to an expansive analysis conducted by researchers at The University of Texas M. D. Anderson Cancer Center.

14 Dec 2007

First view of synapse in real time

For the first time, scientists at Weill Cornell Medical College in New York City have observed in real time a cellular mechanism that's crucial to how brain cells communicate.

14 Dec 2007

Great-grandparent of all the cells of the blood identified

Researchers at the Stanford University School of Medicine have isolated a human blood cell that represents the great-grandparent of all the cells of the blood, a finding that could lead to new treatments for blood cancers and other blood diseases.

13 Dec 2007

Researchers advance stem cell gene therapy

Ireland Cancer Center of University Hospitals Case Medical Center researchers have recently made great strides in stem cell gene therapy research by transferring a new gene to cancer patients, via their own stem cells, with the ultimate goal of being able to use stronger chemotherapy treatment with less severe side effects.

13 Dec 2007

Adult stem cell heart attack study updated

Doctors are using patients' own bone marrow stem cells (progenitor cells) to treat the damage to cardiac muscle after a heart attack in a study at Emory University School of Medicine.

12 Dec 2007

Mild chemo before stem cell transplant causes long-term remission of follicular lymphoma

Treating relapsed follicular lymphoma patients with a milder chemotherapy regimen before they receive a blood stem cell transplant from a donor resulted in long-term complete remission for 45 of 47 patients in a clinical trial, researchers at The University of Texas M. D. Anderson Cancer Center report at the 49th annual meeting of the American Society of Hematology.

10 Dec 2007

Umbilical cord blood transplant may confer advantages over bone marrow transplant for kids with life-threatening metabolic disorders

Children born with inherited metabolic disorders that cause organ failure and early death can be treated successfully with umbilical cord blood transplants from unrelated donors and, in some cases go on to live for many years, according to a study led by Duke University Medical Center researchers.

10 Dec 2007

Children with sickle cell disease, silent strokes show some relief with blood transfusions

A group of children who have sickle cell disease and who experience silent strokes showed some relief from the silent strokes with blood transfusion therapy, researchers at Washington University School of Medicine in St. Louis have found.

10 Dec 2007

New role for miRNA in leukemia discovered

Scientists here have found that mini-molecules called micro-RNA may play a critical role in the progression of chronic myeloid leukemia (CML) from its more treatable chronic phase to a life-threatening phase, called blast crisis.

10 Dec 2007

New understanding of chronic myeloid leukemia

Oregon Health & Science University Cancer Institute researchers have opened a new window into the roots of chronic myeloid leukemia (CML).

10 Dec 2007

Scientists develop optical device that allows them to peer through the eyes of a mouse and monitor cells passing in bloodstream

A team of researchers from the Wellman Center for Photomedicine at Massachusetts General Hospital (MGH) and Harvard Medical School (HMS) have developed an optical device that allows them to peer through the eyes of a mouse and monitor the cells passing through its bloodstream.

4 Dec 2007