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Healthy lifestyle can overcome genetic risk of obesity, new study reveals

Study demonstrates that adherence to a healthy lifestyle can significantly mitigate the genetic risk of obesity and its related morbidities, emphasizing the importance of promoting healthy behaviors irrespective of genetic predisposition.

4 Jul 2024

Decoding cerebellar neural patterns in movement disorders

The cerebellum is a region of the brain that helps us refine our movements and learn new motor skills.

3 Jul 2024

Mapping pathogen spread and evolution using genomic and human mobility data

A new way to map the spread and evolution of pathogens, and their responses to vaccines and antibiotics, will provide key insights to help predict and prevent future outbreaks.

3 Jul 2024

New guidelines provide the first code of practice for use of stem cell-based embryo models

Stem cell-based embryo models (SCBEMs) are three-dimensional biological structures that mimic aspects of early human embryo development.

3 Jul 2024

Machine learning revolutionizes cardiac studies in fruit flies

Drosophila - commonly known as fruit flies - are a valuable model for human heart pathophysiology, including cardiac aging and cardiomyopathy.

3 Jul 2024

Protein nanocages: A promising frontier in mRNA therapeutics

In recent years, messenger RNA (mRNA) has emerged as a promising avenue for accurate and potent therapeutic interventions. Unlike DNA drugs, mRNA can express genetic information without the risk of integrating into the host genome.

3 Jul 2024

Impaired communication between immune cells leads to cognitive impairment in female Alzheimer's patients

Lead author Neta Rosenzweig, PhD, of the Ann Romney Center for Neurological Diseases, and senior author Oleg Butovsky, PhD, of the Ann Romney Center and Gene Lay Institute of Immunology and Inflammation, share key messages from their paper "Sex-Dependent APOE4 Neutrophil-Microglia Interactions Drive Cognitive Impairment in Alzheimer's Disease" published in Nature Medicine.

3 Jul 2024

Key differences in RNA editing found between postmortem and living brain

Researchers examined the adenosine-to-inosine (A-to-I) nucleoside editing of postmortem and live prefrontal cortical tissues.

3 Jul 2024

Gene discovery points to oxytocin for depression

While investigating two boys from different families with severe obesity, anxiety, autism, and behavioural problems triggered by sounds or smells, a team led by scientists at the University of Cambridge, UK, and Baylor College of Medicine, Houston, USA, discovered that the boys were missing a single gene, known as TRPC5, which sits on the X chromosome.

3 Jul 2024

New HIV test targets neglected strains in global cure hunt

A multinational team led by Weill Cornell Medicine investigators developed a test that will help measure the persistence of HIV in people affected by viral strains found predominantly in Africa - a vital tool in the search for an HIV cure that will benefit patients around the world.

3 Jul 2024

Decoding the significance of subnormal liver enzyme activity

Liver diseases are commonly diagnosed using serum enzyme assays, particularly for aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma-glutamyl transpeptidase (GGT), and 5'-nucleotidase (5'-NT).

3 Jul 2024

Ribosomes and ZAK protein spur the cell's initial response to UV radiation damage

In a recent study, researchers at Johns Hopkins Medicine suggest the cell's messenger RNA (mRNA) - the major translator and regulator of genetic material - along with a critical protein called ZAK, spur the cell's initial response to UV radiation damage and play a critical role in whether the cell lives or dies.

2 Jul 2024

Mediterranean diet linked to enhanced longevity, reduced cardiovascular mortality in cancer survivors

The Mediterranean Diet is a powerful ally for health even after a cancer diagnosis. This is the key result of an Italian study carried out as part of the UMBERTO Project, conducted by the Joint Research Platform Umberto Veronesi Foundation - Department of Epidemiology and Prevention of the I.R.C.C.S. Neuromed of Pozzilli, in collaboration with the LUM "Giuseppe Degennaro" University of Casamassima (BA).

2 Jul 2024

TRPC5 gene identified as a diagnostic marker of obesity and postpartum depression

Researchers at Baylor College of Medicine, the University of Cambridge and collaborating institutions have discovered that alterations in the human gene TRPC5 cause obesity and postpartum depression.

2 Jul 2024

Study finds promising new target for the treatment of Alzheimer's disease

A class of proteins that regulates cell repair and enhances cell growth-signaling systems could be a promising new target for the treatment of Alzheimer's and other neurodegenerative diseases, according to a new study led by researchers at Penn State.

2 Jul 2024

Key transcription factor enhances anthocyanin production in wounded grapevines

A recent study sheds light on the biochemical response of grapevines to wounding stress. It reveals that the transcription factor VvWRKY5 is a key regulator that enhances anthocyanin production, which serves as a protective mechanism for the plant.

2 Jul 2024

From Africa to Eurasia: Genetic insights into human migration and cold adaptation

"Who are we and where do we come from?" This quintessential question has intrigued humanity for millennia.

2 Jul 2024

Regular booster doses of bivalent mRNA COVID-19 vaccines help neutralize multiple strains

People who have received solid organ transplants and take immunosuppressant medications to prevent rejection are among those most susceptible to the damaging effects of COVID-19, including breakthrough infections, severe illness, hospitalization and death.

2 Jul 2024

Research paves the way for tailored diets based on individual responses to macronutrients

When it comes to managing blood sugar levels, most people think about counting carbs. But new research from the University of British Columbia shows that, for some, it may be just as important to consider the proteins and fats in their diet.

2 Jul 2024

Modulating gene expression using small molecules

The correct functioning of cells relies heavily on the ability to finely control gene expression, a complex process by which the information contained in DNA is copied into RNA to eventually give rise to all the proteins and most of the regulatory molecules in the cell.

2 Jul 2024

Genetic News and Research

Healthy lifestyle can overcome genetic risk of obesity, new study reveals

Decoding cerebellar neural patterns in movement disorders

Mapping pathogen spread and evolution using genomic and human mobility data

New guidelines provide the first code of practice for use of stem cell-based embryo models

Machine learning revolutionizes cardiac studies in fruit flies

Protein nanocages: A promising frontier in mRNA therapeutics

Impaired communication between immune cells leads to cognitive impairment in female Alzheimer's patients

Key differences in RNA editing found between postmortem and living brain

Gene discovery points to oxytocin for depression

New HIV test targets neglected strains in global cure hunt

Decoding the significance of subnormal liver enzyme activity

Ribosomes and ZAK protein spur the cell's initial response to UV radiation damage

Mediterranean diet linked to enhanced longevity, reduced cardiovascular mortality in cancer survivors

TRPC5 gene identified as a diagnostic marker of obesity and postpartum depression

Study finds promising new target for the treatment of Alzheimer's disease

Key transcription factor enhances anthocyanin production in wounded grapevines

From Africa to Eurasia: Genetic insights into human migration and cold adaptation

Regular booster doses of bivalent mRNA COVID-19 vaccines help neutralize multiple strains

Research paves the way for tailored diets based on individual responses to macronutrients

Modulating gene expression using small molecules

eBook: Using iPSCs models for human disease research and drug discovery eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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