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Study examines how bacteria clog medical devices

A new study has exam-ined how bac-te-ria clog med-ical devices, and the result isn't pretty. The microbes join to cre-ate slimy rib-bons that tan-gle and trap other pass-ing bac-te-ria, cre-at-ing a full block-age in a star-tlingly short period of time.

3 Mar 2013

Global inhibition of all Notch signals would not be safe after bone marrow transplantation

Bone marrow transplant is a key treatment for patients with leukemia, lymphoma, multiple myeloma and other blood disorders. University of Michigan researchers have discovered that inhibiting a signaling pathway in some of the transplanted cells could prevent the most serious potential complications of the procedure, a conflict between the transplanted cells and the recipient's own tissue called graft-versus-host disease.

2 Mar 2013

Melanoma tumours deliberately create conditions that knock out body's premier immune defence

New research in the Journal of Clinical Investigation reveals that tumours in melanoma patients deliberately create conditions that knock out the body's 'premier' immune defence and instead attract a weaker immune response unable to kill off the tumour's cancerous cells.

2 Mar 2013

Three Penn students develop award-winning healthcare technology

Three students at the University of Pennsylvania School of Nursing have developed award-winning healthcare technology.

2 Mar 2013

NO triggers RGS4 degradation to coordinate angiogenesis and cardiomyocyte growth

Myocardial hypertrophy, a thickening of the heart muscle, is an adaptation that occurs with increased stress on the heart, such as high blood pressure. As the heart muscle expands, it also requires greater blood flow to maintain access to oxygen and nutrients, necessitating an expansion of the cardiac vasculature.

2 Mar 2013

New data from KYTHERA Biopharmaceuticals’ ATX-101 studies on double chin

KYTHERA Biopharmaceuticals, Inc. today announced four abstracts will be presented at the 71st American Academy of Dermatology (AAD) Annual Meeting in Miami Beach, Fla.

2 Mar 2013

Cannabis can be detected in blood of chronic daily smokers for a month after last intake

New research appearing online today in Clinical Chemistry, the journal of AACC, shows that cannabis can be detected in the blood of daily smokers for a month after last intake.

2 Mar 2013

RNA interference identifies function of genes linked with cardiovascular disease

Studies screening the genome of hundreds of thousands of individuals (known as Genome-wide association studies or GWAS) have linked more than 100 regions in the genome to the risk of developing cardiovascular disease.

1 Mar 2013

Study identifies six markers in the breath that could become stress-detector

The perennial stress-buster - a deep breath - could become stress-detector, Loughborough University researchers claim. According to a new pilot study, published today, 28 February, in IOP Publishing's Journal of Breath Research, there are six markers in the breath that could be candidates for use as indicators of stress.

1 Mar 2013

Pivotal study of olesoxime in Spinal Muscular Atrophy receives positive interim review

Trophos SA, a clinical stage pharmaceutical company developing innovative therapeutics from discovery to clinical validation for under-served medical needs in neurology and cardiology, announced the completion of the interim analysis of the pivotal efficacy study of olesoxime in the rare neurodegenerative condition Spinal Muscular Atrophy (SMA).

1 Mar 2013

LDL apheresis can reduce cholesterol levels in patients with familial hypercholesterolemia

Some patients are genetically prone to such dangerously high levels of cholesterol that no amount of diet, exercise and medications can reduce their cholesterol to safe levels.

1 Mar 2013

Thyroid hormone may help reduce heart damage in humans with cardiac diseases

Thyroid hormone treatment administered to rats at the time of a heart attack (myocardial infarction) led to significant reduction in the loss of heart muscle cells and improvement in heart function, according to a study published by a team of researchers led by A. Martin Gerdes and Yue-Feng Chen from New York Institute of Technology College of Osteopathic Medicine.

1 Mar 2013

Stem cell line could also advance research into liver cancers, cystic fibrosis

Chronic or acute, liver failure can be deadly. Toxins take over, the skin turns yellow and higher brain function slows. "There is no effective therapy at the moment to deal with the toxins that build up in your body," said Neil Talbot, a Research Animal Scientist for the USDA Agricultural Research Service. "Their only option now is to transplant a liver."

1 Mar 2013

Patients with diabetes at no increased risk of complications after total knee replacement

Patients with diabetes who undergo total knee replacement surgery do not have increased risk of surgical complications compared to those patients without diabetes, according to a Kaiser Permanente study published today in The Journal of Bone and Joint Surgery.

28 Feb 2013

TikoMed, BRI partner to investigate IBsolvMIR in phase II trial for chronic pancreatitis

Baylor Research Institute (BRI), the research arm of Baylor Health Care System, and TikoMed AB announced today that an agreement has been established to investigate TikoMed´s product IBsolvMIR® in a phase II clinical trial.

28 Feb 2013

U-M to study how exercise, other therapies might work differently in lean and obese individuals

Researchers at the University of Michigan School of Kinesiology have received a $1 million grant to study how exercise and other therapies might work differently in lean and obese individuals.

28 Feb 2013

Anti-LG3 associated with high rate of organ rejection during transplantation

A team led by Dr. Marie-Jos-e H-bert from the University of Montreal Hospital* Research Centre (CRCHUM) has discovered a new cause of organ rejection in some kidney transplant patients. Her team has identified a new class of antibodies - anti-LG3 - which when activated lead to severe rejection episodes associated with a high rate of organ loss.

28 Feb 2013

Engineering chemotherapy drugs' shape increases their ability to target and inhibit cancer cells

Bioengineering researchers at University of California, Santa Barbara have found that changing the shape of chemotherapy drug nanoparticles from spherical to rod-shaped made them up to 10,000 times more effective at specifically targeting and delivering anti-cancer drugs to breast cancer cells.

28 Feb 2013

Starch-based intravenous fluids cause unnecessary deaths in seriously ill patients

Starch-based intravenous (IV) fluids used by the NHS to treat seriously ill patients are causing unnecessary deaths, according to a new Cochrane systematic review by researchers at the London School of Hygiene & Tropical Medicine.

28 Feb 2013

Elevated cell sugar concentrations increase hyaluronan production and promote cancer growth

According to a recent University of Eastern Finland (UEF) study, elevated cell sugar concentrations increase the production of hyaluronan which, in turn, promotes cancer growth. Regulating the production of hyaluronan may be a way to prevent the spreading of cancer.

28 Feb 2013

Blood News and Research

Study examines how bacteria clog medical devices

Global inhibition of all Notch signals would not be safe after bone marrow transplantation

Melanoma tumours deliberately create conditions that knock out body's premier immune defence

Three Penn students develop award-winning healthcare technology

NO triggers RGS4 degradation to coordinate angiogenesis and cardiomyocyte growth

New data from KYTHERA Biopharmaceuticals’ ATX-101 studies on double chin

Cannabis can be detected in blood of chronic daily smokers for a month after last intake

RNA interference identifies function of genes linked with cardiovascular disease

Study identifies six markers in the breath that could become stress-detector

Pivotal study of olesoxime in Spinal Muscular Atrophy receives positive interim review

LDL apheresis can reduce cholesterol levels in patients with familial hypercholesterolemia

Thyroid hormone may help reduce heart damage in humans with cardiac diseases

Stem cell line could also advance research into liver cancers, cystic fibrosis

Patients with diabetes at no increased risk of complications after total knee replacement

TikoMed, BRI partner to investigate IBsolvMIR in phase II trial for chronic pancreatitis

U-M to study how exercise, other therapies might work differently in lean and obese individuals

Anti-LG3 associated with high rate of organ rejection during transplantation

Engineering chemotherapy drugs' shape increases their ability to target and inhibit cancer cells

Starch-based intravenous fluids cause unnecessary deaths in seriously ill patients

Elevated cell sugar concentrations increase hyaluronan production and promote cancer growth

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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