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Wyss Founding Director receives NC3Rs 3Rs Prize for Lung-on-a-Chip

In a London ceremony today, Wyss Founding Director Don Ingber, M.D., Ph.D., received the NC3Rs 3Rs Prize from the UK's National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) for his innovative Lung-on-a-Chip -- a microdevice lined by human cells that recapitulates complex functions of the living lung.

28 Feb 2013

Study indicates how gastric bypass reverses diabetes

In a substudy of the STAMPEDE trial (Surgical Therapy And Medications Potentially Eradicate Diabetes Efficiently), Cleveland Clinic researchers have found that gastric bypass surgery reverses diabetes by uniquely restoring pancreatic function in moderately obese patients with uncontrolled type 2 diabetes.

28 Feb 2013

Scientists identify two populations of human cells that migrate to the intestine

Researchers at Wake Forest Baptist Medical Center and colleagues have identified a special population of adult stem cells in bone marrow that have the natural ability to migrate to the intestine and produce intestinal cells, suggesting their potential to restore healthy tissue in patients with inflammatory bowel disease (IBD).

28 Feb 2013

Excess of vitamin D during pregnancy can increase risk of food allergy in children

Pregnant women should avoid taking vitamin D supplements. Substitution appears to raise the risk of children developing a food allergy after birth.

28 Feb 2013

Study designs and tests 60 compounds for their ability to kill human cancer cells

Inspired by a chemical that fungi secrete to defend their territory, MIT chemists have synthesized and tested several dozen compounds that may hold promise as potential cancer drugs.

28 Feb 2013

Long-term treatment with spironolactone improves left ventricular diastolic function in HF patients

Among patients with heart failure with preserved ejection fraction, long-term treatment with the medication spironolactone improved left ventricular diastolic function but did not affect maximal exercise capacity, patient symptoms, or quality of life, according to a study appearing in the February 27 issue of JAMA.

28 Feb 2013

Researchers investigate effects of Mediterranean diet on older people

We are what we eat. However, little is known on how a specific dietary regime can impact the life of the elderly. Now, researchers from an EU funded project called NU-AGE are investigating the effects of the Mediterranean diet on older people. Their aim is to get clues on how to counteract physical and cognitive decline through diet changes.

27 Feb 2013

Two antagonistic proteins help keep leukemia at bay

Two proteins that scientists once thought carried out the same functions are actually antagonists of each other, and keeping them in balance is key to preventing diseases such as cancer, according to new findings published in the February 25 issue of Developmental Cell by scientists at Fox Chase Cancer Center.

27 Feb 2013

Viewpoints: Former Sen. Gramm criticizes Obama on budget cuts; Debate on revamping Medicare needs less heat, more deliberation

While history shows that a divided government can enact significant spending cuts as an alternative to sequesters, that doesn't appear to be the path Mr. Obama intends to follow. Instead of protecting civilian defense workers, the president will continue to force the Pentagon to buy biofuels at $27 per gallon to promote his green agenda.

27 Feb 2013

Molecular effects of insufficient sleep uncovered

Results from a sleep laboratory study show striking changes in gene expression associated with sleep deprivation.

27 Feb 2013

Air pollution from lead-contaminated soil a cause for concern

Research suggests that air pollution from lead-contaminated soil may explain the seasonal variation in blood lead levels observed in children, particularly those living in urban areas.

27 Feb 2013

CellAegis Devices to use autoRIC Device for Chronic Remote Ischemic Conditioning

CellAegis Devices, Inc., announced today that it has received an Investigational Testing Approval from Health Canada that allows the initiation of clinical testing in Canada of the Company's autoRIC Device for Chronic Remote Ischemic Conditioning (CRIC).

27 Feb 2013

Using smart phones to manage HIV treatment in rural Virginia

An innovative plan developed at the University of Virginia School of Medicine will use smart phones to improve care for people recently diagnosed with HIV in rural Virginia.

27 Feb 2013

New findings could help develop treatments for inherited disorders

Fresh insights into the protective seal that surrounds the DNA of our cells could help develop treatments for inherited muscle, brain, bone and skin disorders.

27 Feb 2013

Surgical site infections appear to have significant genetic connections

An estimated 300,000 U.S. patients get surgical site infections every year, and while the causes are varied, a new University of Utah study suggests that some who get an infection can blame it partly on their genes.

27 Feb 2013

Genetic variation in CD33 influences how AML patients' leukemic cell responds to GO

Researchers from the College of Pharmacy and Medical School working within the Masonic Cancer Center, University of Minnesota, have partnered to identify genetic variations that may help signal which acute myeloid leukemia (AML) patients will benefit or not benefit from one of the newest antileukemic agents.

26 Feb 2013

Trends in patient worry and risk-reducing behaviors in women undergoing breast cancer treatment

Women who have had the lymph nodes under their arm surgically removed during breast cancer treatment are warned to avoid certain practices that can cause lymphedema-a condition that causes chronic, painless swelling in the arm.

26 Feb 2013

Cardiometabolic risk prevention opportunity in early schizophrenia

esearchers have found that cardiometabolic risk in patients with schizophrenia is heightened in those with established disease, suggesting a need for early intervention in those presenting with their first episode.

26 Feb 2013

Complementary medicine risks: an interview with Dr Andrew Boyden, NPS MedicineWise

Complementary medicines include products containing herbs, vitamins, minerals, nutritional supplements, homoeopathic medicines, certain aromatherapy products and traditional Chinese medicines. For this reason they are also called herbal, natural or alternative medicines.

26 Feb 2013

One in three ventilated people with ALI shows substantial PTSD symptoms

One in three people who survived stays in an intensive care unit (ICU) and required use of a mechanical ventilator showed substantial post-traumatic stress disorder (PTSD) symptoms that lasted for up to two years, according to a new Johns Hopkins study of patients with acute lung injury.

26 Feb 2013

Blood News and Research

Wyss Founding Director receives NC3Rs 3Rs Prize for Lung-on-a-Chip

Study indicates how gastric bypass reverses diabetes

Scientists identify two populations of human cells that migrate to the intestine

Excess of vitamin D during pregnancy can increase risk of food allergy in children

Study designs and tests 60 compounds for their ability to kill human cancer cells

Long-term treatment with spironolactone improves left ventricular diastolic function in HF patients

Researchers investigate effects of Mediterranean diet on older people

Two antagonistic proteins help keep leukemia at bay

Viewpoints: Former Sen. Gramm criticizes Obama on budget cuts; Debate on revamping Medicare needs less heat, more deliberation

Molecular effects of insufficient sleep uncovered

Air pollution from lead-contaminated soil a cause for concern

CellAegis Devices to use autoRIC Device for Chronic Remote Ischemic Conditioning

Using smart phones to manage HIV treatment in rural Virginia

New findings could help develop treatments for inherited disorders

Surgical site infections appear to have significant genetic connections

Genetic variation in CD33 influences how AML patients' leukemic cell responds to GO

Trends in patient worry and risk-reducing behaviors in women undergoing breast cancer treatment

Cardiometabolic risk prevention opportunity in early schizophrenia

Complementary medicine risks: an interview with Dr Andrew Boyden, NPS MedicineWise

One in three ventilated people with ALI shows substantial PTSD symptoms

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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