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Biologists elucidate how muscle stem cells colonize special niches

Muscles have a pool of stem cells which provides a source for muscle growth and for regeneration of injured muscles. The stem cells must reside in special niches of the muscle for efficient growth and repair.

18 Sep 2012

Two abnormalities associated with cystic fibrosis-related diabetes

A new University of Iowa study suggests there are two root causes of a type of diabetes associated with cystic fibrosis (CF). The findings, which already have sparked a clinical trial, may guide development of new treatments or even help prevent diabetes in patients with CF.

18 Sep 2012

Researchers to probe causes, treatments of toxic reactions in blood plasma

In the largest undertaking of its kind, scientists at four leading U.S. research institutions are embarking upon a five-year National Institutes of Health (NIH)-funded study to make blood transfusions safer and more effective by uncovering the exact causes of hemoglobin toxicity.

18 Sep 2012

EMD Millipore announces global licensing agreement for AJ's iPS cell patent portfolio

EMD Millipore, the Life Science division of Merck KGaA of Darmstadt, Germany, and iPS Academia Japan, Inc. today announced a global licensing agreement for AJ's induced pluripotent stem (iPS) cell patent portfolio.

18 Sep 2012

Important data from Pfizer’s lung cancer and RCC portfolios to be presented at ESMO Congress

Pfizer Oncology today announced that important data from its lung cancer and renal cell carcinoma (RCC) portfolios will be presented at the upcoming European Society for Medical Oncology (ESMO) Congress in Vienna, Austria, September 28 - October 2, 2012.

18 Sep 2012

Researchers obtain first detailed and complete picture of PRC2 protein

The first detailed and complete picture of a protein complex that is tied to human birth defects as well as the progression of many forms of cancer has been obtained by an international team of researchers led by scientists with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab).

18 Sep 2012

Compelling data from two ITS Flunisyn Phase I clinical trials against multiple strains of influenza A

Immune Targeting Systems Limited, an emerging leader in the development of vaccines that promote T-cell responses against viruses and cancers, today announces compelling data from two Phase I clinical trials of FlunisynTM, the Company's lead vaccine programme which elicits potent immune responses against multiple strains of influenza-A virus.

18 Sep 2012

Hemerus Medical’s SOLX red blood cell additive receives world's first CE Marking

Hemerus Medical, LLC, a Minnesota-based company that develops innovative technologies for the collection, processing, preservation, and storage of blood products announced that it has received the world's first CE Marking for a 56 day red blood cell storage solution – the SOLX red blood cell additive (AS-7).

18 Sep 2012

Scripps Florida scientist receives two grants to focus on sulfenylation

A scientist from the Florida campus of The Scripps Research Institute has been awarded a pair of grants totaling $2.8 million from the National Institute of General Medical Sciences of the National Institutes of Health, and from TargAnox, a Massachusetts-based biotechnology firm.

18 Sep 2012

Pertussis immunity wanes in the 5 years after DTaP vaccination

The risk for pertussis infection in children who receive the combined diphtheria, tetanus, and acellular pertussis vaccine increases by an average of 42% per year after the last dose, a US study shows.

17 Sep 2012

Parents of sickle cell babies undercounseled

Parents of newborns with the sickle cell anemia trait are significantly less likely to receive genetic counseling than those of babies who are cystic fibrosis carriers, say researchers.

17 Sep 2012

Refinements in gene therapy prove beneficial for ‘bubble babies’

Results from a long-term study published in Blood show that adding a low dose of chemotherapy prior to gene therapy can help improve outcomes in children with adenosine deaminase-deficient severe combined immunodeficiency.

17 Sep 2012

Single HPV protein is required for cervical cancer growths to survive

Human papillomavirus (HPV) has long been implicated in cervical cancer, but details of how it happens have remained a mystery. Now researchers at the University of Wisconsin-Madison have found that a single HPV protein is required for cervical cancer and even pre-cancer growths in the cervix to survive.

17 Sep 2012

NIH awards ASC grant to study ASC-101-treated amniotic fluid-derived stem cells in compartment syndrome

America Stem Cell, Inc. today announced that it has been awarded an Advanced Technology Small Business Technology Transfer Research (STTR) grant from the National Heart Lung and Blood Institute at the National Institutes of Health.

17 Sep 2012

Researchers identify gene mutations in Wolfram syndrome that affects insulin-secreting beta cells

The rare disorder Wolfram syndrome is caused by mutations in a single gene, but its effects on the body are far reaching. The disease leads to diabetes, hearing and vision loss, nerve cell damage that causes motor difficulties, and early death.

17 Sep 2012

Natural antibiotic to treat tuberculosis

A natural product secreted by a soil bacterium shows promise as a new drug to treat tuberculosis report scientists in a new study published in EMBO Molecular Medicine. A team of scientists working in Switzerland has shown how pyridomycin, a natural antibiotic produced by the bacterium Dactylosporangium fulvum, works.

17 Sep 2012

Novel drug combination for patients with NRAS-mutant melanoma

A new study published online in Nature Medicine, led by scientists at The University of Texas MD Anderson Cancer Center, describes the discovery of a novel drug combination aimed at a subset of melanoma patients who currently have no effective therapeutic options.

17 Sep 2012

Progenra’s P5091 inhibits growth of bortezomib resistant multiple myeloma tumor cells

Researchers at the Dana-Farber Cancer Institute and Progenra, Inc. announce the publication of a research article entitled "A Small Molecule Inhibitor of Ubiquitin-Specific Protease-7 Induces Apoptosis in Multiple Myeloma Cells and Overcomes Bortezomib Resistance."

17 Sep 2012

PARP inhibitors may be novel treatment strategy in women with HER2-positive breast cancers

Poly (ADP-Ribose) polymerase (PARP) inhibitors, shown to have clinical activity when used alone in women with familial breast and ovarian cancers linked to BRCA mutations, may be a novel treatment strategy in women with HER2-positive breast cancers, according to the results of a study published in Cancer Research, a journal of the American Association for Cancer Research.

17 Sep 2012

Breath testing could discriminate between benign and malignant pulmonary nodules

A pilot study, published in the October 2012 issue of the International Association for the Study of Lung Cancer's (IASLC) Journal of Thoracic Oncology, showed that breath testing could be used to discriminate between benign and malignant pulmonary nodules.

17 Sep 2012

B Cell News and Research

Biologists elucidate how muscle stem cells colonize special niches

Two abnormalities associated with cystic fibrosis-related diabetes

Researchers to probe causes, treatments of toxic reactions in blood plasma

EMD Millipore announces global licensing agreement for AJ's iPS cell patent portfolio

Important data from Pfizer’s lung cancer and RCC portfolios to be presented at ESMO Congress

Researchers obtain first detailed and complete picture of PRC2 protein

Compelling data from two ITS Flunisyn Phase I clinical trials against multiple strains of influenza A

Hemerus Medical’s SOLX red blood cell additive receives world's first CE Marking

Scripps Florida scientist receives two grants to focus on sulfenylation

Pertussis immunity wanes in the 5 years after DTaP vaccination

Parents of sickle cell babies undercounseled

Refinements in gene therapy prove beneficial for ‘bubble babies’

Single HPV protein is required for cervical cancer growths to survive

NIH awards ASC grant to study ASC-101-treated amniotic fluid-derived stem cells in compartment syndrome

Researchers identify gene mutations in Wolfram syndrome that affects insulin-secreting beta cells

Natural antibiotic to treat tuberculosis

Novel drug combination for patients with NRAS-mutant melanoma

Progenra’s P5091 inhibits growth of bortezomib resistant multiple myeloma tumor cells

PARP inhibitors may be novel treatment strategy in women with HER2-positive breast cancers

Breath testing could discriminate between benign and malignant pulmonary nodules

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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