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Autifony Therapeutics awarded £2.2 million to progress first-in-class drug for tinnitus into Phase IIa study

Autifony Therapeutics Limited (“Autifony”), which is pioneering the development of novel pharmaceutical treatments for hearing disorders, today announced that it has been awarded funding of £2.2 million towards a Phase IIa clinical trial in tinnitus patients with its lead compound AUT00063, by the UK’s innovation agency, the Technology Strategy Board.

4 Jun 2014

Acadia Healthcare to acquire Partnerships in Care for $660M

Acadia Healthcare Company, Inc. today announced the signing of a definitive agreement to acquire Partnerships in Care (PiC) for approximately $660 million in cash.

3 Jun 2014

NYU Langone scientists identify promising treatment target for Alzheimer's disease

Scientists at NYU Langone Medical Center have identified a compound, called 2-PMAP, in animal studies that reduced by more than half levels of amyloid proteins in the brain associated with Alzheimer's disease.

3 Jun 2014

Study warns against use of resveratrol supplements by pregnant women

A widely available dietary supplement that had been considered safe - and that some claim provides anti-aging and other health benefits - caused significant developmental abnormalities in the pancreas of offspring of pregnant monkeys who were given the supplement, according to a study published today in the FASEB Journal, from the Federation of American Societies of Experimental Biology.

3 Jun 2014

Novartis LDE225 Phase II study for advanced basal cell carcinoma meets primary endpoint

Novartis announced today the results of a pivotal Phase II trial demonstrating that patients with locally advanced (laBCC) or metastatic basal cell carcinoma (mBCC) taking the investigational oral compound LDE225 (sonidegib) had marked and sustained tumor shrinkage after a median follow-up of 13.9 months.

2 Jun 2014

Compound in saliva may protect from toxins in tea, coffee and liquid smoke flavoring

A compound in saliva, along with common proteins in blood and muscle, may protect human cells from powerful toxins in tea, coffee and liquid smoke flavoring, according to results of a new study led by investigators at the Johns Hopkins Kimmel Cancer Center.

2 Jun 2014

AbbVie releases preliminary results from ABT-414 Phase I study in patients with recurrent or unresectable GBM

AbbVie released preliminary results from an ongoing Phase I study with ABT-414, an anti-epidermal growth factor receptor (EGFR) monoclonal antibody drug conjugate, in combination with temozolomide, which showed four objective responses, including one complete response, in patients with recurrent or unresectable glioblastoma multiforme.

31 May 2014

Promedior reports positive preliminary data from PRM-151 Phase 2 trial for myelofibrosis

Promedior, Inc., today announced positive preliminary data from its Phase 2 trial of PRM-151, an anti-fibrotic immunotherapy, in patients with myelofibrosis which demonstrated biologic activity with improvements across clinically relevant measures, including bone marrow fibrosis, hemoglobin, platelets, spleen, and symptoms.

31 May 2014

Research report on sports nutrition market in Europe

Sports Nutrition Market in Europe 2014-2018 has been prepared based on an in-depth market analysis with inputs from industry experts.

31 May 2014

ArQule to present tivantinib clinical trial data at ASCO 2014

ArQule, Inc. today announced that tivantinib will be included in seven presentations during the 2014 Annual Meeting of the American Society of Clinical Oncology (ASCO) to be held from May 30, 2014 to June 3, 2014 in Chicago, Illinois.

31 May 2014

Compound in saliva and proteins in blood may protect human cells from powerful toxins in tea, coffee

31 May 2014

DNA-binding fluorescent dyes evaluate cytotoxicity in real-time during screening

High throughput screening of compounds in live cells is a powerful approach for discovering new drugs, but the potential for cell toxicity must be considered.

31 May 2014

Polyplus-transfection introduces FectoPRO transfection reagent

Polyplus-transfection SA, a privately-held company specializing in the development of innovative solutions for transfection, today announces the launch of FectoPRO, the latest optimised transfection reagent in their product portfolio. FectoPRO has been designed for high yields in medium and large-scale production of proteins and antibodies in mammalian cells.

28 May 2014

Researchers discover how uric acid helps prevent aging and disease

Interested in antioxidants? They protect us against aging and cancer. It's one of the reasons we like our green tea and even our broccoli. But there is a new kid on the antioxidant block - uric acid.

28 May 2014

New fluorescent molecule paves way for easier and higher quality imaging of cells

Like our own bodies, cells have their own skeletons called 'cytoskeletons' and are made of proteins instead of bones.

26 May 2014

Pain receptors may hold key to treating obesity, diabetes and improving metabolic health

Blocking a pain receptor in mice not only extends their lifespan, it also gives them a more youthful metabolism, including an improved insulin response that allows them to deal better with high blood sugar.

23 May 2014

New antibody appears to block sensations of pain, itching in mouse model

Duke University researchers have found an antibody that simultaneously blocks the sensations of pain and itching in studies with mice.

23 May 2014

NCCN receives $2M grant to evaluate effectiveness of volasertib in treatment of hematologic malignancies

The National Comprehensive Cancer Network® (NCCN®) Oncology Research Program (ORP) has been awarded a $2-million grant from Boehringer Ingelheim Pharmaceuticals, Inc.

23 May 2014

Research findings could lead to new approach to Alzheimer’s prevention

In surprise findings, scientists at The Scripps Research Institute have discovered that a protein with a propensity to form harmful aggregates in the body when produced in the liver protects against Alzheimer’s disease aggregates when it is produced in the brain. The results suggest that drugs that can boost the protein’s production specifically in neurons could one day help ward off Alzheimer’s disease.

22 May 2014

Drugs that boost protein's production in neurons could help ward off Alzheimer's disease

In surprise findings, scientists at The Scripps Research Institute (TSRI) have discovered that a protein with a propensity to form harmful aggregates in the body when produced in the liver protects against Alzheimer's disease aggregates when it is produced in the brain.

22 May 2014

Compound News and Research

Autifony Therapeutics awarded £2.2 million to progress first-in-class drug for tinnitus into Phase IIa study

Acadia Healthcare to acquire Partnerships in Care for $660M

NYU Langone scientists identify promising treatment target for Alzheimer's disease

Study warns against use of resveratrol supplements by pregnant women

Novartis LDE225 Phase II study for advanced basal cell carcinoma meets primary endpoint

Compound in saliva may protect from toxins in tea, coffee and liquid smoke flavoring

AbbVie releases preliminary results from ABT-414 Phase I study in patients with recurrent or unresectable GBM

Promedior reports positive preliminary data from PRM-151 Phase 2 trial for myelofibrosis

Research report on sports nutrition market in Europe

ArQule to present tivantinib clinical trial data at ASCO 2014

Compound in saliva and proteins in blood may protect human cells from powerful toxins in tea, coffee

DNA-binding fluorescent dyes evaluate cytotoxicity in real-time during screening

Polyplus-transfection introduces FectoPRO transfection reagent

Researchers discover how uric acid helps prevent aging and disease

New fluorescent molecule paves way for easier and higher quality imaging of cells

Pain receptors may hold key to treating obesity, diabetes and improving metabolic health

New antibody appears to block sensations of pain, itching in mouse model

NCCN receives $2M grant to evaluate effectiveness of volasertib in treatment of hematologic malignancies

Research findings could lead to new approach to Alzheimer’s prevention

Drugs that boost protein's production in neurons could help ward off Alzheimer's disease

Advancing therapeutic biopolymer development eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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