Inflammation News and Research

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TBI-on-a-chip model traces link between head trauma and Alzheimer's

How much time elapses between a blow to the head and the start of damage associated with Alzheimer's disease?

29 Aug 2023

Researchers elucidate the mode of action of cannabinoids in inflammation

A few days ago, the federal government took the controversial decision to make the acquisition and possession of small amounts of cannabis exempt from punishment.

29 Aug 2023

ARAMIS trial finds no benefit of anakinra in acute myocarditis

The largest randomized controlled trial of patients with acute myocarditis has found that anakinra is safe but does not reduce complications. The late breaking research presented in a Hot Line session today at ESC Congress 2023.

29 Aug 2023

SGLT2 inhibitors do not reduce 28-day mortality in hospitalized COVID-19 patients

Sodium glucose co-transporter-2 (SGLT2) inhibitors do not lead to lower 28-day all-cause mortality compared with usual care or placebo in patients hospitalized with COVID-19, according to late-breaking research presented in a Hot Line session today at ESC Congress 2023.

29 Aug 2023

Microplastics found to bioaccumulate in every organ of mice

Plastics - in particular, microplastics - are among the most pervasive pollutants on the planet, finding their way into the air, water systems and food chains around the world.

29 Aug 2023

An update on the health benefits of olive oil

Researchers summarize recent evidence on the clinical impact of olive oil on human health.

29 Aug 2023

Non-alcoholic steatohepatitis progression blocked by ginger essential oil

Researchers explore the potential utility of ginger essential oil in preventing NASH.

29 Aug 2023

Study unveils previously unknown urinary biomarkers, revolutionizing early detection and treatment of viral infections like COVID-19

This recent study identifies new urinary biomarkers for detecting acute COVID-19 using spectroscopic analysis. The findings reveal that these biomarkers could offer valuable tools for early diagnosis, understanding the severity of the disease, and possibly contribute to endogenous immunological defense mechanisms against SARS-CoV-2.

29 Aug 2023

Inflammatory diets raise dementia and Alzheimer's risk

This research study links higher Dietary Inflammatory Index (DII) scores to an increased risk of developing dementia, specifically Alzheimer's disease. The findings suggest that anti-inflammatory diets may offer a preventive strategy for dementia, underlining the need for further research to validate these associations.

28 Aug 2023

Smartphone-based imaging reveals a breakthrough in identifying infected wounds

A recent study in "Frontiers in Medicine" evaluates the use of hyperspectral imaging (HSI) through a smartphone-based device to differentiate between infected and non-infected wounds. The study found that this portable approach offered 74% accuracy in wound assessment, including 100% sensitivity and 91% specificity in detecting infected wounds.

28 Aug 2023

How diet and exercise may rewrite the Alzheimer's script at a molecular level

Researchers explore how lifestyle changes like diet and physical activity can influence microRNA expression in Alzheimer's patients, potentially offering new therapeutic avenues. The study fills a research gap in understanding how such lifestyle modifications could affect molecular mechanisms implicated in Alzheimer’s disease.

28 Aug 2023

The potential of targeting mitochondria-associated programmed cell death for age-related disease treatment

The review summarized the involvement of mitochondria in age-related disease progression and highlighted its potential as a therapeutic target of these diseases.

28 Aug 2023

Research links hypertensive disorders of pregnancy with dementia

Hypertensive disorders of pregnancy (HDP) — conditions of high blood pressure including chronic/gestational hypertension and preeclampsia — have been strongly linked to heart disease in later life, but, before today, little research has connected these disorders with cognition.

28 Aug 2023

The potential of gut-microbiota-targeted reprogramming interventions designed to prevent the onset and progression of cardiovascular diseases

Researchers discuss the potential of probiotic- and prebiotic-based interventions for managing cardiovascular diseases.

28 Aug 2023

Time-restricted feeding reverses Alzheimer's symptoms in mice, offers new hope for accessible treatment

Researchers explore the therapeutic potential of circadian-modulating interventions to treat Alzheimer’s disease.

27 Aug 2023

Adolescence stress exposure impacts rodent brain development and behavior

Adolescence stress exposure in rodents can lead to reduced hippocampal cell proliferation, neuroplasticity, and cognitive impairments, as well as increased depressive-like behaviors. These effects may persist into adulthood but with variable impact.

27 Aug 2023

UofL researchers receive $11.7 million to study microorganisms throughout the body

University of Louisville researchers have received $11.7 million to study microorganisms throughout the body, including the mouth. What they find could lead to better understanding and treatment of a range of chronic conditions.

25 Aug 2023

New 3D model mimics brain cell and immune cell interactions in Alzheimer's disease

Cognitive decline associated with Alzheimer's disease (AD) develops when neurons begin to die, which can be caused by inappropriate immune responses and excessive inflammation in the brain triggered by amyloid beta deposits and tau tangles, two hallmarks of the disease.

25 Aug 2023

Colchicine does not reduce perioperative AF or MINS in major non-cardiac thoracic surgery

Colchicine does not significantly reduce perioperative atrial fibrillation (AF) or myocardial injury after non-cardiac surgery (MINS) in patients undergoing major non-cardiac thoracic surgery, according to late breaking research presented in a Hot Line session today at ESC Congress 2023.

25 Aug 2023

Semaglutide could be a game-changer for patients with HFpEF and obesity

Semaglutide improves heart failure-related symptoms and physical function and results in greater weight loss compared with placebo in patients with heart failure with preserved ejection fraction (HFpEF) and obesity, according to late-breaking research presented in a Hot Line session today at ESC Congress 2023.

25 Aug 2023

Inflammation News and Research

TBI-on-a-chip model traces link between head trauma and Alzheimer's

Researchers elucidate the mode of action of cannabinoids in inflammation

ARAMIS trial finds no benefit of anakinra in acute myocarditis

SGLT2 inhibitors do not reduce 28-day mortality in hospitalized COVID-19 patients

Microplastics found to bioaccumulate in every organ of mice

An update on the health benefits of olive oil

Non-alcoholic steatohepatitis progression blocked by ginger essential oil

Study unveils previously unknown urinary biomarkers, revolutionizing early detection and treatment of viral infections like COVID-19

Inflammatory diets raise dementia and Alzheimer's risk

Smartphone-based imaging reveals a breakthrough in identifying infected wounds

How diet and exercise may rewrite the Alzheimer's script at a molecular level

The potential of targeting mitochondria-associated programmed cell death for age-related disease treatment

Research links hypertensive disorders of pregnancy with dementia

The potential of gut-microbiota-targeted reprogramming interventions designed to prevent the onset and progression of cardiovascular diseases

Time-restricted feeding reverses Alzheimer's symptoms in mice, offers new hope for accessible treatment

Adolescence stress exposure impacts rodent brain development and behavior

UofL researchers receive $11.7 million to study microorganisms throughout the body

New 3D model mimics brain cell and immune cell interactions in Alzheimer's disease

Colchicine does not reduce perioperative AF or MINS in major non-cardiac thoracic surgery

Semaglutide could be a game-changer for patients with HFpEF and obesity

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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