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Study identifies Etravirine and Dolutegravir as effective entry inhibitors of wild-type and predominant variants of SARS-CoV-2

Researchers identified drugs inhibiting the entry of SARS-CoV-2.

18 Apr 2022

Mutation-acquiring potential of coronaviruses and efficacies of current COVID-19 vaccines against parent and mutant strains of SARS-CoV-2

Researchers reviewed the antibody resistance exhibited by SARS-CoV-2 variants.

18 Apr 2022

Monoclonal antibodies from COVID-19 convalescent donors target conserved site

Researchers found six monoclonal antibodies binding to the spike proteins of all human coronaviruses.

18 Apr 2022

SARS-CoV-2 RBD is a selective integrin agonist

Researchers assess the Arg-Gly-Asp (RGD) motif-mediated binding of the SARS-CoV-2 RBD and integrin receptors.

18 Apr 2022

Scientists investigate how gut bacteria directly control the activity of specific neurons

Gut microbiota by-products circulate in the bloodstream, regulating host physiological processes including immunity, metabolism and brain functions.

15 Apr 2022

Role of cGAS-STING in SARS-CoV-2 infection

A new study analyzes the activation of cGAS and STING can induce a type I IFN response due to SARS-CoV-2 infection.

15 Apr 2022

A comprehensive rule book for the design of safe and efficient therapeutic cells

Therapies based on engineered immune cells have recently emerged as a promising approach in the treatment of cancer.

15 Apr 2022

Comparison of neutralizing antibody response following SARS-CoV-2 booster vaccination with breakthrough infection

A new study examined the serological immune responses and antibody-dependent cell-mediated phagocytosis in individuals who had either received two doses of a standard vaccine regime, a booster dose following the regime, or a breakthrough infection following vaccination.

15 Apr 2022

Orally delivered temperature-stable tablet vaccine efficacy against SARS-CoV-2 and other respiratory infections

Researchers assessed the protective efficacy of the temperature-stable orally delivered vaccines against respiratory viral pathogens.

14 Apr 2022

Exploring strategies for successful delivery of messenger RNA therapeutics

Researchers reviewed the material properties and administration routes that could successfully deliver a messenger ribonucleic acid therapeutic agent to its targeted site.

14 Apr 2022

The preclinical potential of S. miltiorrhiza extracts for the treatment of COVID-19

In a recent study, researchers assessed the anti-COVID-19 efficacy of Salvia miltiorrhiza Bunge.

14 Apr 2022

COVID-19 may affect a group of biochemical reactions called one-carbon metabolism

A new study addresses the relationship between SARS-CoV-2 to the metabolism of one-carbon molecules in the host, suggesting new therapeutic pathways.

13 Apr 2022

Dietary influences on long COVID in children

A new study discusses possible mechanisms of long COVID in children and how they might relate to their dietary intake of important vitamins and elements.

13 Apr 2022

Structural differences between SARS-CoV-1 and SARS-CoV-2 RBDs

A new study compares the SARS-CoV-2 RBD to the SARS-CoV RBD using computational methods to understand their binding affinities to ACE2.

13 Apr 2022

Novel transdermal vaccine delivery for COVID-19 and cancer

Researchers assess the efficacy of a fluorocarbon modified chitosan system for the development of SARS-CoV-2 vaccines and tumor immunotherapy.

13 Apr 2022

Mayo Clinic researchers devise a combination approach to more effectively target solid tumors

Researchers at Mayo Clinic's Center for Individualized Medicine have devised an immunotherapy technique that combines chimeric antigen receptor-T cell therapy, or CAR-T cell therapy, with a cancer-killing virus to more effectively target and treat solid cancer tumors.

13 Apr 2022

Receptor News and Research

Study identifies Etravirine and Dolutegravir as effective entry inhibitors of wild-type and predominant variants of SARS-CoV-2

Mutation-acquiring potential of coronaviruses and efficacies of current COVID-19 vaccines against parent and mutant strains of SARS-CoV-2

Monoclonal antibodies from COVID-19 convalescent donors target conserved site

SARS-CoV-2 RBD is a selective integrin agonist

Scientists investigate how gut bacteria directly control the activity of specific neurons

Role of cGAS-STING in SARS-CoV-2 infection

A comprehensive rule book for the design of safe and efficient therapeutic cells

Comparison of neutralizing antibody response following SARS-CoV-2 booster vaccination with breakthrough infection

Orally delivered temperature-stable tablet vaccine efficacy against SARS-CoV-2 and other respiratory infections

Exploring strategies for successful delivery of messenger RNA therapeutics

The preclinical potential of S. miltiorrhiza extracts for the treatment of COVID-19

COVID-19 may affect a group of biochemical reactions called one-carbon metabolism

Dietary influences on long COVID in children

Structural differences between SARS-CoV-1 and SARS-CoV-2 RBDs

Novel transdermal vaccine delivery for COVID-19 and cancer

Mayo Clinic researchers devise a combination approach to more effectively target solid tumors

Researchers find novel inhibitors that may suppress oncogenesis of metastatic prostate cancer

Impact of COVID-19 infection and vaccination on antibody response

The molecular context and substrate profiles of human cell surface receptor tyrosine kinases

Epigenetics likely to be the reason why lung cancer patients develop treatment resistance

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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