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Mcl-1 gene essential for survival of antibody-producing cells

Scientists have identified the gene essential for survival of antibody-producing cells, a finding that could lead to better treatments for diseases where these cells are out of control, such as myeloma and chronic immune disorders.

3 Feb 2013

Study shows how placental circulation can influence malarial parasite behavior and infection

Malaria in pregnancy causes a range of adverse effects, including abortions, stillbirths, premature delivery and low infant birth weight. Many of these effects are thought to derive from a placental inflammatory response resulting from interaction of infected red blood cells with the placental tissue.

3 Feb 2013

Epidermal growth factor speeds recovery of blood-making stem cells after radiation exposure

Epidermal growth factor has been found to speed the recovery of blood-making stem cells after exposure to radiation, according to Duke Medicine researchers. The finding could open new options for treating cancer patients and victims of dirty bombs or nuclear disasters.

3 Feb 2013

High intensity interval training more suitable to achieve sustainable changes in exercise behaviour

With many of us struggling to get enough exercise, sport and exercise scientists at Liverpool John Moores University (LJMU) and the University of Birmingham, under the lead of Professor Anton Wagenmakers, have been working on a time-saving solution.

3 Feb 2013

New drug to prevent early stages of Alzheimer's could enter clinical trials soon

A new drug to prevent the early stages of Alzheimer's disease could enter clinical trials in a few years' time according to scientists.

2 Feb 2013

Scientists identify cause of certain forms of epilepsy in cats

There is something sinister about epilepsy: the disease affects the very core of our being, our brain. Epileptic attacks can lead to seizures throughout the body or in parts of it. Clouding of consciousness or memory lapses are also possible. The causes are still only partially understood but in some cases brain tumours, infections, inflammations of the brain or metabolic diseases have been implicated.

2 Feb 2013

Potential connection between autism and insulin-like growth factor

A New York-based physician-researcher from Touro College of Osteopathic Medicine, best known for his research into fertility and twinning, has uncovered a potential connection between autism and a specific growth protein that could eventually be used as a way to predict an infant's propensity to later develop the disease.

2 Feb 2013

Hyperion Therapeutics receives FDA approval for Ravicti to treat urea cycle disorders

The U.S. Food and Drug Administration today approved Ravicti (glycerol phenylbutyrate) for the chronic management of some urea cycle disorders (UCDs) in patients ages 2 years and older.

1 Feb 2013

Scientists uncover key mechanism that links obesity and diabetes with cancer

Sugars are needed to provide us with energy and in moderate amounts contribute to our well-being. Sustained high levels of sugars, as is found in diabetics, damages our cells and now is shown that can also increase our chance to get cancer: The dose makes the poison as Paracelsus said.

1 Feb 2013

Cedars-Sinai healthcare professionals to mark National Wear Red Day

Hundreds of healthcare professionals at the Cedars-Sinai Heart Institute will wear red on Friday, Feb. 1, to mark National Wear Red Day. A few hours later, the new Cedars-Sinai Advanced Health Sciences Pavilion will be lit with a projection of the red dress symbol that represents a public education program to boost women's awareness of heart disease.

1 Feb 2013

Two-step personalized immunotherapy safe for patients with ovarian cancer

Most ovarian cancer patients are diagnosed with late stage disease that is unresponsive to existing therapies. In a new study, researchers from the Perelman School of Medicine at the University of Pennsylvania School of Medicine show that a two-step personalized immunotherapy treatment - a dendritic cell vaccine using patients' own tumor followed by adoptive T cell therapy - triggers anti-tumor immune responses in these type of patients.

1 Feb 2013

Study investigates R1441G mutation of Parkinson's disease

A team from the UPV/EHU-University of the Basque Country came across a mutation of the LRRK2 gene in 2004, which is particularly prevalent among the population of Gipuzkoa. It is the R1441G mutation and is known as the Basque mutation.

1 Feb 2013

Endothelial cells can trigger changes in cancer cells without direct contact

Blood vessels that supply oxygen and nutrients to tumors can also deliver something else - a signal that strengthens nearby cancer cells, making them more resistant to chemotherapy, more likely to spread to other organs and more lethal, scientists at The University of Texas MD Anderson Cancer Center report online in Cancer Cell.

1 Feb 2013

Notch protein responsible for activating GATA2 gene to generate hematopoietic stem cells

Researchers from the group on stem cells and cancer at IMIM (Hospital del Mar Medical Research Institute) have deciphered one of the gene regulation circuits which would make it possible to generate hematopoietic blood cells, i.e. blood tissue stem cells.

1 Feb 2013

Merck full-year 2012 worldwide sales decrease 2% to $47.3 billion

Merck, known as MSD outside the United States and Canada, today announced financial results for the fourth quarter and full year of 2012.

1 Feb 2013

Family history one of the strongest predictors of heart disease

Sherron Simmons lived her life as the picture of good health: she exercised regularly, ate healthy and did not smoke. That is why it was a shock for her to learn in 2007 that the main left artery to her heart was 90 percent blocked.

1 Feb 2013

University of Leicester's GENIE to host Lifestyle and Cancer Awareness Workshop on Feb. 23

Women with a family history of breast or ovarian cancer are invited to meet with experts who will advise on preventing or delaying the disease. The University of Leicester's Genetics Education Networking for Innovation and Excellence (GENIE) will hold its third Lifestyle and Cancer Awareness Workshop on Saturday, February 23.

1 Feb 2013

Study expands and deepens biological and genetic links between CVD and schizophrenia

A new study, to be published in the Feb. 7, 2013 issue of the American Journal of Human Genetics, expands and deepens the biological and genetic links between cardiovascular disease and schizophrenia. Cardiovascular disease (CVD) is the leading cause of premature death among schizophrenia patients, who die from heart and blood vessel disorders at a rate double that of persons without the mental disorder.

1 Feb 2013

FDA allows Arteriocyte to commence Magellan System Phase I trial in thermal burn wounds

Arteriocyte, a leading biotechnology company with offices in Cleveland, Ohio and Hopkinton, Massachusetts announced today approval from the Food and Drug Administration (FDA) to initiate a Phase I clinical trial using its Magellan System technology in the treatment of thermal burn wounds.

31 Jan 2013

Resonance Health receives FDA marketing authorization for FerriScan R2-MRI device

The U.S. Food and Drug Administration recently announced the authorization of FerriScan R2-MRI to be marketed as an imaging companion diagnostic device for the safe and effective use of Exjade in patients with non-transfusion-dependent thalassemia.

31 Jan 2013

Blood News and Research

Mcl-1 gene essential for survival of antibody-producing cells

Study shows how placental circulation can influence malarial parasite behavior and infection

Epidermal growth factor speeds recovery of blood-making stem cells after radiation exposure

High intensity interval training more suitable to achieve sustainable changes in exercise behaviour

New drug to prevent early stages of Alzheimer's could enter clinical trials soon

Scientists identify cause of certain forms of epilepsy in cats

Potential connection between autism and insulin-like growth factor

Hyperion Therapeutics receives FDA approval for Ravicti to treat urea cycle disorders

Scientists uncover key mechanism that links obesity and diabetes with cancer

Cedars-Sinai healthcare professionals to mark National Wear Red Day

Two-step personalized immunotherapy safe for patients with ovarian cancer

Study investigates R1441G mutation of Parkinson's disease

Endothelial cells can trigger changes in cancer cells without direct contact

Notch protein responsible for activating GATA2 gene to generate hematopoietic stem cells

Merck full-year 2012 worldwide sales decrease 2% to $47.3 billion

Family history one of the strongest predictors of heart disease

University of Leicester's GENIE to host Lifestyle and Cancer Awareness Workshop on Feb. 23

Study expands and deepens biological and genetic links between CVD and schizophrenia

FDA allows Arteriocyte to commence Magellan System Phase I trial in thermal burn wounds

Resonance Health receives FDA marketing authorization for FerriScan R2-MRI device

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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