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Lack of exercise, television viewing associated with risk of metabolic syndrome

A team of scientists at Umeå University, in collaboration with colleagues in Melbourne, Australia, have found that television viewing and lack of exercise at age 16 is associated with the risk of developing metabolic syndrome at 43 years age.

30 Jan 2013

Coming out might offer health benefits for lesbians, gays and bisexuals

30 Jan 2013

Dilaforette receives approval to initiate sevuparin Phase II malaria study in India

Dilaforette, a Karolinska Development portfolio company, today announces that the company has approval from the regulatory authority in India to start a Phase II study with sevuparin in patients with moderate to severe malaria.

30 Jan 2013

Hydrogen sulfide may play a wide-ranging role in staving off aging

Hydrogen sulfide (H2S) may play a wide-ranging role in staving off aging, according to a paper published online ahead of print in the journal Molecular and Cellular Biology.

30 Jan 2013

Massage therapy can lower blood pressure, help prevent colds and enhance skin tone

Massage therapy can lower blood pressure, help prevent colds, enhance skin tone and more, according to an expert at the University of Alabama at Birmingham (UAB).

30 Jan 2013

ADRB receptors play a direct role in Src activation by PKA-mediated mechanism

Scientists at The University of Texas MD Anderson Cancer Center have discovered the signaling pathway whereby a master regulator of cancer cell proteins - known as Src - leads to ovarian cancer progression when exposed to stress hormones. The researchers report in the current issue of Nature Communications that beta blocker drugs mitigate this effect and reduce cancer deaths by an average of 17 percent.

30 Jan 2013

DFG again approves funding for Mainz University to promote cardiovascular research

The German Research Foundation (DFG) has again approved funding for the Department of Internal Medicine II of the Mainz University Medical Center to promote cardiovascular research - for the second time within only a few weeks.

30 Jan 2013

FDA approves Genzyme’s KYNAMRO to treat homozygous familial hypercholesterolemia

Genzyme, a Sanofi company, and Isis Pharmaceuticals Inc., today announced that the U.S. Food and Drug Administration (FDA) has approved its New Drug Application (NDA) for KYNAMROTM (mipomersen sodium) injection.

30 Jan 2013

Acceleron commences ACE-536 phase 2 study in myelodysplastic syndromes

Acceleron Pharma, Inc., a biopharmaceutical company developing protein therapeutics for cancer and orphan diseases, today announced the initiation of a phase 2 study of its investigational protein therapeutic, ACE-536, to treat anemia in patients with myelodysplastic syndromes (MDS).

30 Jan 2013

Mice with mitochondrial mutation live longer, have less fat

If findings of a new study in mice are any indication, it might be possible to fine-tune cellular powerhouses called mitochondria, tweaking one aspect to increase insulin sensitivity, reduce body and fat mass, and even extend life. Exploiting this target could one day lead to novel treatments for type 2 diabetes - an endocrine system disease that affects 8 percent of the U.S. population. The research also points to promising new avenues of investigation in the biology of aging.

30 Jan 2013

Sanofi introduces LeGoo gel to temporarily stop blood flow during cardiovascular surgery

Sanofi US announced the commercial launch of LeGoo, a biopolymer gel that allows surgeons to temporarily stop blood flow during surgery without the use of clamps, elastic loops or other conventional occlusion devices, which may increase risk of trauma to blood vessels.

30 Jan 2013

Genzyme receives FDA approval for Kynamro to treat homozygous familial hypercholesterolemia

The U.S. Food and Drug Administration today approved Kynamro (mipomersen sodium) injection as an addition to lipid-lowering medications and diet to treat patients with a rare type of high cholesterol called homozygous familial hypercholesterolemia (HoFH).

30 Jan 2013

Controlling blood pressure and cholesterol may reduce risk of heart attack or stroke in diabetics

For people with diabetes, meeting the recommended guidelines for blood pressure and cholesterol is even more important than meeting the guidelines for blood sugar control in reducing the risk of heart attack or stroke, according to a new Kaiser Permanente study published today in the Journal of General Internal Medicine.

29 Jan 2013

Tacrolimus breast milk transfer concerns allayed

Breastfeeding mothers taking tacrolimus do not pass the immunosuppressant on to their babies when breastfeeding, study results show.

29 Jan 2013

U-M researchers develop new method thet could enhance gene sequencing data

When researchers sequence the RNA of cancer cells, they can compare it to normal cells and see where there is more RNA. That can help lead them to the gene or protein that might be triggering the cancer.

29 Jan 2013

German Research Foundation approves funding for Mainz study on cardiovascular disorders

The German Research Foundation has approved funding for the Department of Internal Medicine II of the Mainz University Medical Center to promote the further study of the interrelations between the immune system and cardiovascular system disorders.

29 Jan 2013

Study finds reduction in salt intake among England people after national campaign

The number of people in England adding salt to food at the table fell by more than a quarter in the five years following a national campaign, according to research published in the British Journal of Nutrition.

29 Jan 2013

Colorectal cancer screening: an interview with Dr Donato F. Altomare

Colorectal cancer is a malignant neoplasm affecting the large bowel and the rectum mainly after the 5th decade of life and representing the second cause of death for cancer in western countries (the third in women). In about 15-20% of patients there is an inherited predisposition.

29 Jan 2013

Double transplants can be successful with donor lungs from heavy smokers

Lungs from carefully selected donors with a heavy smoking history can be used with good results in adult, double-lung transplants, according to a study released today at the 49th Annual Meeting of The Society of Thoracic Surgeons held at the Los Angeles Convention Center.

29 Jan 2013

Coming out of the closet helps reduce depressive symptoms and allostatic load levels in LGBs

Lesbians, gays and bisexuals (LGBs) who are out to others have lower stress hormone levels and fewer symptoms of anxiety, depression, and burnout, according to researchers at the Centre for Studies on Human Stress (CSHS) at Louis H. Lafontaine Hospital, affiliated with the University of Montreal. Cortisol is a stress hormone in our body. When chronically strained, cortisol contributes to the 'wear and tear' exerted on multiple biological systems. Taken together, this strain is called "allostatic load".

29 Jan 2013

Blood News and Research

Lack of exercise, television viewing associated with risk of metabolic syndrome

Coming out might offer health benefits for lesbians, gays and bisexuals

Dilaforette receives approval to initiate sevuparin Phase II malaria study in India

Hydrogen sulfide may play a wide-ranging role in staving off aging

Massage therapy can lower blood pressure, help prevent colds and enhance skin tone

ADRB receptors play a direct role in Src activation by PKA-mediated mechanism

DFG again approves funding for Mainz University to promote cardiovascular research

FDA approves Genzyme’s KYNAMRO to treat homozygous familial hypercholesterolemia

Acceleron commences ACE-536 phase 2 study in myelodysplastic syndromes

Mice with mitochondrial mutation live longer, have less fat

Sanofi introduces LeGoo gel to temporarily stop blood flow during cardiovascular surgery

Genzyme receives FDA approval for Kynamro to treat homozygous familial hypercholesterolemia

Controlling blood pressure and cholesterol may reduce risk of heart attack or stroke in diabetics

Tacrolimus breast milk transfer concerns allayed

U-M researchers develop new method thet could enhance gene sequencing data

German Research Foundation approves funding for Mainz study on cardiovascular disorders

Study finds reduction in salt intake among England people after national campaign

Colorectal cancer screening: an interview with Dr Donato F. Altomare

Double transplants can be successful with donor lungs from heavy smokers

Coming out of the closet helps reduce depressive symptoms and allostatic load levels in LGBs

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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