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Surgeons warn: Skateboarding tough on feet, ankles

Children and young adults love the thrill of skateboarding. They learn to master their skills of "riding the rail" and "catching air." But according to the American College of Foot and Ankle Surgeons (ACFAS), such tricks, while fun, can be physically demanding and cause serious foot and ankle injuries.

30 Jun 2009

Newly discovered gene regulates balance of 'bad' cholesterol

In an article in Science, Noam Zelcer from the LACDR describes a previously unknown mechanism for regulating the amount of LDL cholesterol. This offers opportunities for supplementing and improving the effect of so-called statins: medicines that remove 'bad' cholesterol from the bloodstream.

30 Jun 2009

Optimizing the start time of statin therapy for diabetics

Researchers from North Carolina State University and Mayo Clinic have developed a computer model that medical doctors can use to determine the best time to begin using statin therapy in diabetes patients to help prevent heart disease and stroke.

30 Jun 2009

Rotator cuff calcific tendonitis

A minimally invasive procedure to treat tendonitis in the rotator cuff of the shoulder provides immediate symptom relief to the patient, according to a study published in the July issue of Radiology. The study found that ultrasound-guided nonsurgical therapy significantly reduces pain from calcific tendonitis of the rotator cuff and restores lasting mobility after treatment.

30 Jun 2009

Deep brain stimulation for psychiatric disorders

Pioneering therapeutic trials to investigate the effectiveness of deep brain stimulation (DBS) in hard-to-treat depression, obsessive-compulsive disorder (OCD) and Tourette's syndrome are underway at multiple medical centers around the world, according to a review in the June 2009 issue of Mayo Clinic Proceedings.

30 Jun 2009

Insect venom shots work for severe "local" sting reactions, too

The same bee and other insect venom shots that doctors use to prevent deadly systemic reactions to insect stings can also tone down large local allergic reactions that, while not dangerous, can be painful and inconvenient, a Johns Hopkins study shows. Results of the study are published in the June 2009 Journal of Allergy and Clinical Immunology.

29 Jun 2009

Researchers test whether estrogen could improve outcomes after traumatic brain injury, shock

UT Southwestern Medical Center researchers are conducting two pilot clinical trials to determine whether a single, early dose of estrogen can improve survival and neurological outcomes after severe traumatic brain injury or traumatic hemorrhagic shock.

29 Jun 2009

California Rulings: State can cut Medi-Cal benefits but not home care wages

"A federal judge on Thursday blocked a $2 hourly wage cut for California in-home care workers that was slated to begin July 1, potentially increasing California's budget deficit by another $98 million," The Sacramento Bee reports.

29 Jun 2009

Cognitive behavioural therapy for major psychiatric disorder: does it really work?

Research co-led by an academic at the University of Hertfordshire, concludes that Cognitive Behavioural Therapy (CBT) is of no value in schizophrenia and has limited effect on depression.

28 Jun 2009

Recent trends in breast cancer incidence in U.S. white women by urban/rural and poverty status

The recent decline in invasive breast cancer in the US was significantly less pronounced in the poor and those who live in rural areas. Researchers writing in the open access journal BMC Medicine suggest this may be due to varying reductions in the numbers of women taking hormone therapy (HT).

28 Jun 2009

Golimumab shows promise for rheumatoid arthritis

Golimumab, a new tumour necrosis factor-α (TNF-α) inhibitor reduces the signs and symptoms of rheumatoid arthritis in patients who have previously received any other TNF-α inhibitor, and might be a good option for patients who have inadequate responses to one or two other TNF-α inhibitors, finds an Article published Online first and in this week's edition of The Lancet.

28 Jun 2009

'Trojan horse' cancer therapy beats tumours resistant to chemotherapy

A new therapy to treat cancer has been developed by Australian scientists and it promises to have far fewer unpleasant side effects than conventional treatments and should also be much cheaper.

28 Jun 2009

Roche files MabThera as a first-line biologic treatment for rheumatoid arthritis in Europe

Roche has announced that it has submitted a combined filing to the European health authorities (the European Medicines Agency) for three new indications to extend the label for MabThera to use as a first-line biologic therapy for patients with rheumatoid arthritis (RA).

28 Jun 2009

Multiparameter computational modeling of tumor invasion

Tumors are complex collections of cells whose behavior has proven difficult to understand, let alone predict. As a result, oncologists are often surprised by how a particular patient responds to a given course of therapy.

28 Jun 2009

Expanding quantum dot utility in cancer diagnosis and treatment

Quantum dots (QDs), nanoparticles that shine with extraordinary brightness when excited by light energy, have shown promise as new tools for detecting cancer at its earliest appearance, but concerns about potential toxicities have limited their clinical development. Researchers at the University of Buffalo may have found an answer to this limitation with their development of a new way to create QDs.

28 Jun 2009

Nanofluidic biopsy detects subtle changes in cancer cells

By taking two standard laboratory techniques - capillary electrophoresis and antibody-based protein detection - and shrinking them to the nanoscale, researchers at the Stanford University School of Medicine have created a new method for detecting miniscule changes in the levels of proteins associated with cancer.

28 Jun 2009

Harnessing nanoparticles to track cancer cell changes

The more dots there are, the more accurate a picture you get when you connect them. Cancer researchers adopting that philosophy have developed a new imaging technology that could give scientists the ability to simultaneously measure as many as 100 or more distinct features in or on a single cell. In a disease such as cancer, that capability would provide a much better picture of what is going on in individual tumor cells.

28 Jun 2009

Early detection of pancreatic cancer closer thanks to multifunctional nanoparticles

Pancreatic cancer has a devastatingly low survival rate (less than 5 percent after 5 years) because it is usually diagnosed at an advanced stage. The initial symptoms, such as pain, jaundice, or weight loss, often do not allow the disease to be caught early enough for surgery and chemotherapy to be effective.

28 Jun 2009

Computer-guided nanoparticle therapy destroys tumors

Gold nanoshells are among the most promising new nanoscale therapeutics being developed to kill tumors, acting as antennas that turn light energy into heat that cooks cancer to death. Now, a multi-institutional research team has shown that polymer-coated gold nanorods one-up their spherical counterparts, with a single dose completely destroying all tumors in a nonhuman animal model of human cancer.

28 Jun 2009

Electrothermally driven micropumps for medicine

In biomedicine and biotechnology the smallest, complex, compound sample quantities must be reliably processed. Microsystems with new mechanisms of action for pumping, filtering and separating will manage this task with great efficiency in the future.

25 Jun 2009