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Perceived barriers to treatment for adolescent depression

Although teen depression poses a widespread problem for which proven treatments exist, few depressed teens receive any care.

26 May 2009

Nervous system may be culprit in Pompe disease

Brain may win out over brawn as the primary cause of breathing problems in children with a severe form of muscular dystrophy known as Pompe disease.

25 May 2009

Heart protein saves muscle

A heart muscle protein can replace its missing skeletal muscle counterpart to give mice with myopathy a long and active life, show Nowak et al. The findings will be published online on Monday, May 25, 2009 and will appear in the June 1, 2009 print issue of the Journal of Cell Biology.

25 May 2009

Bioniche updates on phase III clinical trial with Urocidin in non-muscle-invasive bladder cancer

Bioniche Life Sciences Inc. has provided an update on its Phase III clinical program evaluating Urocidin(TM) in the treatment of bladder cancer. On March 31st, the Company announced that recruitment had been completed in its initial Phase III registration trial evaluating Urocidin in the treatment of non-muscle-invasive bladder cancer that is refractory (unresponsive) to the current standard immunotherapy - Bacillus Calmette-Guérin (BCG).

25 May 2009

Zyflamend, herb-based therapeutic shows promise for high risk of prostate cancer

Results of a phase I clinical trial of a novel herb-based therapeutic called Zyflamend have demonstrated that the therapy is associated with minimal toxicity and no serious adverse events in men at high-risk for developing prostate cancer.

22 May 2009

Majority of HIV-positive pregnant women in developing world lack access to PMTCT services, report says

Two-thirds of HIV-positive pregnant women in the developing world do not have access to treatment to prevent mother-to-child HIV transmission, which could lead to 370,000 new HIV cases annually among infants, according to a study released Thursday by the International Treatment Preparedness Coalition, Bloomberg reports (Chase, Bloomberg, 5/21).

22 May 2009

Tamed virus wipes out cancer safely

Cancer Research UK scientists have tamed a virus so that it attacks and destroys cancer cells but does not harm healthy cells, according to a paper published in PLoS Pathogens, today.

22 May 2009

Viral Genetics issued patent for novel cancer therapies

Biotechnology firm Viral Genetics, Inc. has been issued a patent for novel cancer therapies. The patent protects cancer drugs that have been tested in pre-clinical research studies in mice. Issued on March 31, 2009, the U.S. Patent Number is: 7,510,710. Additional patents directed at generic classes of the drugs are still pending.

22 May 2009

Cancer drugs erlotinib and gefitinib might treat alcoholism

A class of drugs already approved as cancer treatments might also help to beat alcohol addiction. That's the conclusion of a discovery in flies of a gene, dubbed happyhour, that has an important and previously unknown role in controlling the insects' response to alcohol.

22 May 2009

Simple genetic test determines transplant drug tolerance

A simple genetic test can determine a kidney transplant patient's tolerance for a potent anti-rejection medication, according to an upcoming study in the Journal of the American Society Nephrology (JASN). The test could allow doctors to individualize each patient's dose, optimizing the drug's benefits and minimizing its side effects.

22 May 2009

Overnight dialysis more convenient and effective

Overnight dialysis is more convenient for some patients and offers significant benefits over shorter daytime treatments, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN).

22 May 2009

Researchers discuss combined approach to maximize benefits and minimize risks of stem cell therapy

Once placed into a patient's body, stem cells intended to treat or cure a disease could end up wreaking havoc simply because they are no longer under the control of the clinician.

22 May 2009

African-American women breast cancer sufferers often refuse chemotherapy and radiation therapy

A new study finds that nearly one in four African American women with late stage breast cancer refused chemotherapy and radiation therapy, potentially life saving therapies.

22 May 2009

Aspirin and an anti-clotting drug ‘combo’ reduces risk of dialysis access failure

For the first time, a combination of aspirin and the anti-platelet drug dipyridamole has been shown to significantly reduce blockages and extend the useful life of new artery-vein access grafts used for hemodialysis, according to a study by the Dialysis Access Consortium (DAC).

21 May 2009

Novel method stimulates growth of new neurons in adult brain

University at Buffalo researchers have identified a new mechanism that plays a central role in adult brain stem cell development and prompts brain stem cells to differentiate into neurons.

21 May 2009

Study offers new insights into morphine-induced tolerance and increased pain sensitivity

A study published in the June issue of Anesthesiology has shown that a drug metabolite of the opioid morphine may be a key factor in the paradoxical increased sensitivity to pain caused by chronic morphine use. For the first time, this metabolite (called morphine-6 glucuronide, or M6G) was shown to act independently of the pain receptors typically targeted during morphine administration.

21 May 2009

Robotic therapy for cerebral palsy

Over the past few years, MIT engineers have successfully tested robotic devices to help stroke patients learn to control their arms and legs. Now, they're building on that work to help children with cerebral palsy.

20 May 2009

People with Down syndrome may have more cancer-protective genes

Most cancers are rare in people with Down syndrome, whose overall cancer mortality is below 10 percent of that in the general population. Since they have an extra copy of chromosome 21, it's been proposed that people with Down syndrome may be getting an extra dose of one or more cancer-protective genes.

20 May 2009

Methylene blue in combo with new malaria drugs curbs the spread of malaria parasites

New combinations of agents based on the oldest synthetic malaria drug, the methylene blue stain, can curb the spread of malaria parasites and make a significant contribution to the long-term eradication called for by the international "Roll Back Malaria Initiative."

20 May 2009

Vitamin D may halt lung function decline in asthma and COPD

Vitamin D may slow the progressive decline in the ability to breathe that can occur in people with asthma as a result of human airway smooth muscle (HASM) proliferation, according to researchers at the University of Pennsylvania.

20 May 2009

Therapy News and Research

Perceived barriers to treatment for adolescent depression

Nervous system may be culprit in Pompe disease

Heart protein saves muscle

Bioniche updates on phase III clinical trial with Urocidin in non-muscle-invasive bladder cancer

Zyflamend, herb-based therapeutic shows promise for high risk of prostate cancer

Majority of HIV-positive pregnant women in developing world lack access to PMTCT services, report says

Tamed virus wipes out cancer safely

Viral Genetics issued patent for novel cancer therapies

Cancer drugs erlotinib and gefitinib might treat alcoholism

Simple genetic test determines transplant drug tolerance

Overnight dialysis more convenient and effective

Researchers discuss combined approach to maximize benefits and minimize risks of stem cell therapy

African-American women breast cancer sufferers often refuse chemotherapy and radiation therapy

Aspirin and an anti-clotting drug ‘combo’ reduces risk of dialysis access failure

Novel method stimulates growth of new neurons in adult brain

Study offers new insights into morphine-induced tolerance and increased pain sensitivity

Robotic therapy for cerebral palsy

People with Down syndrome may have more cancer-protective genes

Methylene blue in combo with new malaria drugs curbs the spread of malaria parasites

Vitamin D may halt lung function decline in asthma and COPD

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