Fatigue News and Research

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Astellas, Medivation submit European Marketing Authorization Application for XTANDI capsules

Astellas Pharma Inc. and Medivation Inc. today announced the submission of a variation to amend the European Marketing Authorization Application for XTANDI® (enzalutamide) capsules for the treatment of adult men with metastatic castration-resistant prostate cancer (mCRPC) who are asymptomatic or mildly symptomatic after failure of androgen deprivation therapy and in whom chemotherapy is not yet clinically indicated.

4 Apr 2014

Researchers identify possible way to prevent headaches of climbers

By monitoring blood flow in the brains of six climbers scaling Mount Kilimanjaro in Tanzania, German medical researchers have identified a possible way to prevent the headaches that are a common feature of altitude sickness. This work appears in the latest issue of JNIRS—Journal of Near Infrared Spectroscopy.

4 Apr 2014

Neuroinflammation levels higher in patients with chronic fatigue syndrome

Researchers at the RIKEN Center for Life Science Technologies, in collaboration with Osaka City University and Kansai University of Welfare Sciences, have used functional PET imaging to show that levels of neuroinflammation, or inflammation of the nervous system, are higher in patients with chronic fatigue syndrome than in healthy people.

4 Apr 2014

Aortic valve replacement now possible without open-heart surgery

Loyola University Medical Center is the first hospital in Illinois to implant a newly approved aortic heart valve device that does not require open surgery.

From Medtronic 4 Apr 2014

Kessler Foundation receives grant to study effect of speed of processing training on cognitive performance in MS

Kessler Foundation received a four-year $750,000 grant from the National Multiple Sclerosis Society to conduct a randomized controlled trial of speed of processing training to improve cognition in multiple sclerosis (MS).

3 Apr 2014

Frail elderly people are at increased risk of death from outbreaks of viral gastroenteritis

Frail elderly people living in residential care facilities are at increased risk of severe illness or death from outbreaks of viral gastroenteritis.

3 Apr 2014

Vestiage completes R&D for two new products

Vestiage™, Inc., the emerging leader in healthy aging, announced today that it has completed R&D for two new products that it intends to launch in upcoming quarters.

2 Apr 2014

Bayer’s Adempas now available in the UK to treat patients with CTEPH

Adempas (riociguat) is available in the UK today as the first drug treatment for CTEPH, to treat adult patients with WHO Functional Class (FC) II to III with inoperable or persistent disease to improve exercise capacity.

1 Apr 2014

Injecting bone marrow derived stem cells directly into heart muscle improves heart function

Patients with severe ischemic heart disease and heart failure can benefit from a new treatment in which stem cells found in bone marrow are injected directly into the heart muscle, according to research presented at the American College of Cardiology's 63rd Annual Scientific Session.

1 Apr 2014

Kessler Foundation receives Collaborative MS Research Center Award

Kessler Foundation is the recipient of a MS Research Center Award from the National Multiple Sclerosis Society. John DeLuca, PhD, is principal investigator for the five-year $821,000 grant, which will fund the MS Collaborative Network of New Jersey. The MSCNNJ will bring together the Foundation's experts in mobility and cognitive research to advance understanding of cognitive-motor interaction in MS. Dr. DeLuca is Senior Vice President of Research and Training at the Foundation.

1 Apr 2014

e-Therapeutics announces interim results from ETS2101 phase Ia trial for advanced solid tumours

e-Therapeutics plc announced today interim results from its phase Ia UK study evaluating the safety, dosing and anti-tumour activity of ETS2101 (dexanabinol) in patients with advanced solid tumours.

31 Mar 2014

Forest Laboratories, Richter report positive results from cariprazine Phase IIb trial for bipolar depression

Forest Laboratories, Inc. and Gedeon Richter Plc. today announced positive topline results from a Phase IIb trial evaluating the efficacy and safety of the investigational antipsychotic cariprazine in patients with bipolar depression.

31 Mar 2014

CDC program provides natural self-management techniques for people living with arthritis

In the United States, March is Women's History Month. While it is a time to reflect on the contributions women have made to the fields of politics, art, science, medicine and elsewhere, it is also a time to pay attention to the issues that women today are facing in their daily lives.

29 Mar 2014

Study links effect of gastric bypass surgery on glucose metabolism and islet function in hypoglycemia patients

University of Cincinnati (UC) researchers have discovered that altered islet cell function and reduced insulin clearance contribute to excessive post-meal insulin response in patients experiencing low blood sugar symptoms (hypoglycemia) following gastric bypass surgery.

29 Mar 2014

Biogen Idec's ALPROLIX receives FDA approval for hemophilia B treatment

Today Biogen Idec announced that the U.S. Food and Drug Administration has approved ALPROLIX [Coagulation Factor IX (Recombinant), Fc Fusion Protein], the first recombinant, DNA derived hemophilia B therapy with prolonged circulation in the body.

29 Mar 2014

Veterans who suffer from "Gulf War illness" have impaired function of mitochondria

Researchers at the UC San Diego School of Medicine have demonstrated for the first time that veterans of the 1990-91 Persian Gulf War who suffer from "Gulf War illness" have impaired function of mitochondria - the energy powerhouses of cells.

28 Mar 2014

Novartis’ investigational compound achieves overall response rate of 58% in patients with ALK+ NSCLC

Novartis today announced that The New England Journal of Medicine (NEJM) published clinical trial results showing the investigational compound LDK378 (ceritinib) achieved an overall response rate (ORR, including complete response [CR] and partial response [PR]) of 58% and a median progression-free survival (PFS) of seven months in adults with advanced anaplastic lymphoma kinase positive (ALK+) non-small cell lung cancer (NSCLC) who received 400 mg or higher of LDK378 per day.

28 Mar 2014

CDC identifies six new cases of people with Heartland virus

The Centers for Disease Control and Prevention in collaboration with health officials in Missouri and Tennessee have identified six new cases of people sick with Heartland virus: five in Missouri and one in Tennessee. The new cases, discovered in 2012 and 2013, are described today in CDC's Morbidity and Mortality Weekly Report.

28 Mar 2014

Scientists discover role of protons in neurotransmission

While probing how organisms sense gravity and acceleration, scientists at the Marine Biological Laboratory (MBL) and the University of Utah uncovered evidence that acid (proton concentration) plays a key role in communication between neurons.

27 Mar 2014

Too-restricted hours may work for some residents, but not for surgical residents

Strictly limiting the number of hours surgical residents can work has not improved patient outcomes but may have increased complications for some patients and led to higher failure rates on certification exams, a research paper concludes.

27 Mar 2014

Fatigue News and Research

Astellas, Medivation submit European Marketing Authorization Application for XTANDI capsules

Researchers identify possible way to prevent headaches of climbers

Neuroinflammation levels higher in patients with chronic fatigue syndrome

Aortic valve replacement now possible without open-heart surgery

Kessler Foundation receives grant to study effect of speed of processing training on cognitive performance in MS

Frail elderly people are at increased risk of death from outbreaks of viral gastroenteritis

Vestiage completes R&D for two new products

Bayer’s Adempas now available in the UK to treat patients with CTEPH

Injecting bone marrow derived stem cells directly into heart muscle improves heart function

Kessler Foundation receives Collaborative MS Research Center Award

e-Therapeutics announces interim results from ETS2101 phase Ia trial for advanced solid tumours

Forest Laboratories, Richter report positive results from cariprazine Phase IIb trial for bipolar depression

CDC program provides natural self-management techniques for people living with arthritis

Study links effect of gastric bypass surgery on glucose metabolism and islet function in hypoglycemia patients

Biogen Idec's ALPROLIX receives FDA approval for hemophilia B treatment

Veterans who suffer from "Gulf War illness" have impaired function of mitochondria

Novartis’ investigational compound achieves overall response rate of 58% in patients with ALK+ NSCLC

CDC identifies six new cases of people with Heartland virus

Scientists discover role of protons in neurotransmission

Too-restricted hours may work for some residents, but not for surgical residents

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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