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Simple blood test proves powerful ally in the fight against malaria

Scientists at the Swedish medical university Karolinska Institutet have shown that rapid diagnostic tests (RDT) for malaria infection can provide valuable support for healthcare in low and mid-income countries in the fight against the disease.

30 Apr 2009

Protein effects of hormone replacement therapy uncovered

An in-depth proteomic analysis of the sera of 50 participants from the Women's Health Initiative (WHI) hormone replacement therapy trial provides some explanations for the trial's clinical results.

30 Apr 2009

Gene alterations associated with response to anthracycline therapy for breast cancer

Alterations in the topoisomerase II alpha (TOP2A) gene were associated with better patient outcomes following anthracycline-based therapy compared with non-anthracycline-based regimens, according to a study in the April 28 online issue of the Journal of the National Cancer Institute.

30 Apr 2009

Full kidney removal is not always the best treatment for small renal tumors

Nephron-sparing treatments, such as partial nephrectomy, thermal ablation and active surveillance, minimize these risks and are viable options for patients with early-stage (T1a) kidney tumors, according to a new clinical guideline issued by the American Urological Association (AUA).

30 Apr 2009

Rapid malaria tests improve health outcomes in practice

A new study, carried out in primary care units in Zanzibar and published in this week's issue of PLoS Medicine, evaluates the impact of rapid malaria tests on prescribing practice and clinical outcomes.

30 Apr 2009

Sublingual immunotherapy for inhalant allergies deserves deeper consideration

Sublingual immunotherapy for the treatment of allergy symptoms caused by a wide variety of environmental inhalants has been effectively used in Europe.

30 Apr 2009

Risk factors identified for ventilator-associated pneumonia

Ventilator-associated pneumonia (VAP) is the main cause of nosocomial infection in patients undergoing major heart surgery.

29 Apr 2009

First molecular-level numerical study of gene therapy

In a recent issue of The Journal of Chemical Physics , published by the American Institute of Physics (AIP), a group of researchers at the University of California, Berkeley and Los Alamos National Laboratory describe the first comprehensive, molecular-level numerical study of gene therapy.

29 Apr 2009

Discovery of possible preventative therapy for type 1 diabetes

Scientists believe they may have found a preventative therapy for type 1 diabetes, by making the body's killer immune cells tolerate the insulin-producing cells they would normally attack and destroy, prior to disease onset.

29 Apr 2009

Experimental immunotherapy significantly prolongs survival in men with advanced prostate cancer

Sipuleucel-T (Provenge), an experimental immunotherapy improved survival in men with metastatic disease, according to new results to be presented April 28 at the American Urological Association (AUA) Annual Scientific Meeting in Chicago.

29 Apr 2009

Researchers investigate the effects of oxytocin on human couple interactions

Relationships are difficult and most of us probably think at some point that communicating positively with our partner when discussing stressful issues, like home finances, is an impossible task.

29 Apr 2009

Dendrimers as synthetic gene vectors

29 Apr 2009

Research looks at UVB therapy for psoriasis

Ultraviolet light is a proven treatment for psoriasis, one of humanity's oldest known diseases.

29 Apr 2009

Glutamate identified as predictor of disease progression in multiple sclerosis

UCSF researchers have identified a correlation between higher levels of glutamate, which occurs naturally in the brain as a byproduct of metabolism, and greater disease burden in multiple sclerosis patients.

29 Apr 2009

DNA "barcodes" used to map mosquito species in West Africa that spread lymphatic filariasis

New biotechnologies that allow scientists to quickly and accurately distinguish species based on a simple DNA analysis are being creatively deployed for the first time in the war against a major global disease.

29 Apr 2009

Anti-viral drug telaprevir improves response, halves duration of hepatitis C treatment

The addition of the anti-viral drug telaprevir to a standard treatment for hepatitis C can shorten the duration of therapy and increase the number of patients who can be cured of their disease, according to the results of study coordinated by investigators from the Duke Clinical Research Institute (DCRI).

29 Apr 2009

Wyeth's Conbriza (bazedoxifene) approved in Europe for postmenopausal osteoporosis

Wyeth Pharmaceuticals has announced that the European Commission has granted marketing authorization for Conbriza (bazedoxifene), a selective estrogen receptor modulator (SERM), for the treatment of postmenopausal osteoporosis in women at increased risk of fracture.

27 Apr 2009

Voice response system useful for monitoring anticoagulant patients

Interactive voice response systems may help improve monitoring of patients taking anticoagulants such as warfarin while reducing the workload of clinical staff, found a study by Ottawa researchers in CMAJ.

27 Apr 2009

$Prostate cancer therapy increases risk of fractures and cardiovascular-related death$

Prostate cancer therapy increases risk of fractures and cardiovascular-related death

Prostate cancer patients who undergo therapy to decrease testosterone levels increase their risk of developing bone- and heart-related side effects compared to patients who do not take these medications, according to a new analysis.

27 Apr 2009

Research sheds new light on causes of sepsis

New research from Lucile Packard Children's Hospital and the Stanford University School of Medicine is helping physicians unravel the cause of a deadly and mysterious bowel disease that strikes medically fragile newborn babies.

27 Apr 2009