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MRI: Effective tool for determining pathologic stage of prostate cancer

In patients with prostate cancer undergoing prostatectomy, MR imaging plays an important role in determining if the cancer is restricted to the prostate gland or if it has spread beyond the capsule, according to a study performed at the University of California, Los Angeles, Los Angeles, CA.

23 Apr 2009

Significant advance in generating induced pluripotent stem cells

In a paper publishing online April 23rd in Cell Stem Cell , a Cell Press journal, Dr. Sheng Ding and colleagues from the Scripps Research Institute in La Jolla, California, report an important step forward in the race to make reprogrammed stem cells that may be better suited for use in clinical settings.

23 Apr 2009

Discrepancies between reports of HRT dangers and supporting data

In recent years, a series of highly publicized reports have warned of increases in breast cancer and other health problems in postmenopausal women who take hormone replacement therapy (HRT).

23 Apr 2009

Breakthrough in generating safer, therapeutic stem cells from adult cells

The new technique solves one of the most challenging safety hurdles associated with personalized stem cell-based medicine because for the first time it enables scientists to make stem cells in the laboratory from adult cells without genetically altering them.

23 Apr 2009

In-body stem cell therapy has enormous potential for bone injuries

Rarely will physicians use the word "miraculous" when discussing patient recoveries. But that's the very phrase orthopaedic physicians and scientists are using in upstate New York to describe their emerging stem cell research that could have a profound impact on the treatment of bone injuries. Results from preliminary work being released today, patients confined to wheelchairs were able to walk or live independently again because their broken bones finally healed.

23 Apr 2009

Malaria death in Zambia decline by 66%

Malaria deaths reported from health facilities in Zambia have declined by 66%. This result along with other supporting data indicates that Zambia has reached the 2010 Roll Back Malaria target of a more than 50% reduction in malaria mortality compared to 2000.

23 Apr 2009

Hormone therapy may lower colorectal cancer risk in women

In a large study, a national team of researchers led by Mayo Clinic scientists observed that self-reported use of hormone therapy was associated with a significantly lower colorectal cancer risk.

22 Apr 2009

Lymphocytes promote cancer spread

Researchers at the UC San Diego School of Medicine and the Moores UCSD Cancer Center have new evidence that a type of immune system cell thought to be part of the first line of defense against breast cancer may also help promote its spread.

22 Apr 2009

Scientists make significant strides in identifying cause of bacterial infections

Several bacterial pathogens use toxins to manipulate human host cells, ultimately disturbing cellular signal transduction.

22 Apr 2009

Type of physician certification associated with risk of complications from ICDs

Patients whose implantable cardioverter-defibrillators (ICDs) are implanted by nonelectrophysiologists are at increased risk of complications and are less likely to receive a specific type of ICD when clinically indicated, according to a study in the April 22/29 issue of JAMA.

22 Apr 2009

Peregrine's PS-targeting antibodies highlighted in AACR Annual Meeting studies

Peregrine Pharmaceuticals, Inc. has reported that two preclinical studies presented during the AACR 100th Annual Meeting 2009 provided further confirmation of the immunomodulatory mechanisms contributing to the anti-tumor activity of its phosphatidylserine (PS) targeting antibodies.

22 Apr 2009

Discovery of genetic pattern that may predict response to Gleevec in GIST

Researchers at Fox Chase Cancer Center uncovered a genetic pattern that may help predict how gastrointestinal stromal tumor (GIST) patients respond to the targeted therapy imatinib mesylate (Gleevec).

22 Apr 2009

Novel microparticle-based immune response modifier shows broad effects against recurrent or metastatic cancer

MIS416, a novel microparticle-based immune response modifier, demonstrated the ability to significantly reduce the number and size of metastatic tumors in preclinical mouse models of lung and breast cancers, Innate Therapeutics (formerly Virionyx Corporation) announced.

22 Apr 2009

Light-scattering techniques may help determine chemo's effectiveness

By examining the patterns in which light bounces off cell surfaces, researchers may be able to assess chemotherapy's success in inducing cancer cell death, according to a study led by investigators in the Duke Comprehensive Cancer Center and Duke's Pratt School of Engineering.

22 Apr 2009

$Hypofractionated stereotactic radiotherapy beneficial for recurrent low-grade glioma$