G Protein News and Research

RSS

Scientists identify gene mutation linked to anaplastic oligodendroglioma

Scientists have identified a gene mutation linked to the development of an aggressive form of brain cancer. Researchers found that errors in a gene known as TCF12 - which plays a key role in the formation of the embryonic brain are associated with more aggressive forms of a disease called anaplastic oligodendroglioma.

12 Jun 2015

α-synuclein conformation may underlie neurodegenerative variability

Varying structural conformations of α-synuclein may explain how one protein can give rise to distinct forms of neurodegeneration, say researchers.

12 Jun 2015

Early neuronal lysosomal dysfunction could help predict AD

Blood levels of altered lysosomal proteins may help detect preclinical Alzheimer’s disease, researchers report.

12 Jun 2015

Prion variant offers “dramatic” protection against prion disease

A naturally occurring variant of the human prion protein is not only resistant to conversion into an abnormal form but also prevents the conversion of wild-type proteins, shows a study in Nature.

12 Jun 2015

New therapy for osteoporosis may be in the pipeline

Researchers from The Scripps Research Institute (TSRI), Florida, have reported a novel therapeutic approach that could promote the formation of new bone cells in people suffering from bone loss.

12 Jun 2015

Researchers discover new aspect of gene regulation

Researchers at the Max F. Perutz Laboratories of the University of Vienna and the Medical University of Vienna as well as at the University of Natural Resources and Life Sciences in Vienna have discovered an entirely new aspect of gene regulation they call exitron splicing.

12 Jun 2015

Weill Cornell scientists reveal how XBP1 gene can trigger immune responses against ovarian tumors

Ovarian cancer shuts down immune system cells that would otherwise act as a first line of defense against the deadly tumor, Weill Cornell Medical College scientists report today. But a therapy that restores the cells' disease-fighting abilities could provide a powerful new strategy to attack the cancer, which kills more than 14,000 women each year.

12 Jun 2015

Sebia’s Capillarys 3 Tera automated electrophoresis solution receives CE mark

Sebia, the world leader in capillary electrophoresis, today announces that Capillarys 3 Tera now has the CE mark for HbA1c and serum protein testing, and immunotyping. The CE mark for these tests is the first step in bringing the Capillarys 3 suite to market.

12 Jun 2015

Certain ARID1a mutations sensitize some tumors to PARP inhibitor drugs

Mutations in ARID1a, which are common in many cancer types, disrupt DNA damage repair in cancer cells, allowing the cancer to progress. This gene may also be an Achilles' heel when treating certain tumors, according to a team of researchers at The University of Texas MD Anderson Cancer Center.

12 Jun 2015

Discovery may help scientists attack the root of deadliest brain tumors

Some brain tumors are notoriously difficult to treat. Whether surgically removed, zapped by radiation or infiltrated by chemotherapy drugs, they find a way to return. The ability of many brain tumors to regenerate can be traced to cancer stem cells that evade treatment and spur the growth of new tumor cells.

11 Jun 2015

Dietary compounds in milk-based products may protect against cardiovascular risk

The Maillard reaction is a chemical reaction between amino acids and reducing sugars that results in browned foods like seared steaks and toasted bread. When proteins and sugars are mixed together and heated, new chemical compounds are formed. Some are responsible for new flavors and some, according to a new study published in the Journal of Dairy Science, may protect us against cardiovascular disease.

11 Jun 2015

NeoGenomics announces launch of new NeoLAB assays to diagnose hematologic diseases

NeoGenomics, Inc., a leading provider of cancer-focused genetic testing services, announced today the launch of its first twelve tests in a new line of "liquid biopsy" or NeoLAB assays using next generation sequencing and other advanced molecular technologies.

11 Jun 2015

SQUIRE phase III study shows necitumumab improves median overall survival in squamous NSCLC patients

This week, Lancet Oncology reports results of a 1,093-person phase III clinical trial of the drug necitumumab (IMC-11F8) combined with chemotherapies gemcitabine and cisplatin against stage IV squamous non-small cell lung cancer. With addition of necitumumab, median overall survival was 11.5 months compared with median survival of 9.9 months with the two chemotherapies alone.

11 Jun 2015

Protein-signaling process accelerates work of gene mutation linked to common form of adult leukemia

In preliminary experiments with mice and lab-grown cells, Johns Hopkins Kimmel Cancer Center scientists have found that a protein-signaling process accelerates the work of the gene most frequently mutated in a common form of adult leukemia and is likely necessary to bring about the full-blown disease.

11 Jun 2015

Specialized brain proteins may be detected in the blood samples of individuals with Alzheimer's disease

Specialized brain proteins that are involved in the removal of damaged nerve cell materials may be detected in the blood of people who were diagnosed with mild cognitive impairment or dementia due to Alzheimer's disease.

11 Jun 2015

New insights on crop-rotation resistant rootworms may help develop sustainable agricultural practices

After decades of effort, scientists are finally figuring out how insects develop resistance to environmentally friendly farming practices - such as crop rotation - that are designed to kill them. The researchers say their insights will help develop more sustainable agricultural practices.

11 Jun 2015

Two fragile X proteins play crucial role in proper development of neurons

Fragile X syndrome is the most common inherited intellectual disability and the greatest single genetic contributor to autism. Unlocking the mechanisms behind fragile X could make important revelations about the brain.

11 Jun 2015

Ixekizumab drug shows quick and extensive improvements in patients with psoriasis

A University of Manchester led trial of a new psoriasis drug has resulted in 40 percent of people showing a complete clearance of psoriatic plaques after 12 weeks of treatment and over 90 percent showing improvement.

11 Jun 2015

TSRI scientists awarded $2.1 million grant to study protein closely linked to Parkinson's disease

Scientists from the Florida campus of The Scripps Research Institute have been awarded $2.1 million from the National Institute of Neurological Disorders and Stroke of The National Institutes of Health (NIH) to study a protein that has been closely linked in animal models to Parkinson's disease and Huntington's disease.

10 Jun 2015

Creative Diagnostics announces launch of antibody generation service based on DNA immunization technology

Creative Diagnostics, the global diagnostics service and product supplier, is pleased to announce its launch of custom antibody production service based on DNA immunization technology. This DNA immunization technology allows high success rate in generation of high-affinity antibodies recognizing difficult-to-express proteins in their native confirmation, such as GPCRs, ion channels and other multiple membrane spanning proteins.

10 Jun 2015

G Protein News and Research

Scientists identify gene mutation linked to anaplastic oligodendroglioma

α-synuclein conformation may underlie neurodegenerative variability

Early neuronal lysosomal dysfunction could help predict AD

Prion variant offers “dramatic” protection against prion disease

New therapy for osteoporosis may be in the pipeline

Researchers discover new aspect of gene regulation

Weill Cornell scientists reveal how XBP1 gene can trigger immune responses against ovarian tumors

Sebia’s Capillarys 3 Tera automated electrophoresis solution receives CE mark

Certain ARID1a mutations sensitize some tumors to PARP inhibitor drugs

Discovery may help scientists attack the root of deadliest brain tumors

Dietary compounds in milk-based products may protect against cardiovascular risk

NeoGenomics announces launch of new NeoLAB assays to diagnose hematologic diseases

SQUIRE phase III study shows necitumumab improves median overall survival in squamous NSCLC patients

Protein-signaling process accelerates work of gene mutation linked to common form of adult leukemia

Specialized brain proteins may be detected in the blood samples of individuals with Alzheimer's disease

New insights on crop-rotation resistant rootworms may help develop sustainable agricultural practices

Two fragile X proteins play crucial role in proper development of neurons

Ixekizumab drug shows quick and extensive improvements in patients with psoriasis

TSRI scientists awarded $2.1 million grant to study protein closely linked to Parkinson's disease

Creative Diagnostics announces launch of antibody generation service based on DNA immunization technology

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer

Latest News