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Study offers new insights into why some CAR T-cells persist in children with leukemia

New insights explaining why some children have a longer remission than others after having cutting-edge CAR T-cell therapy for leukemia have been revealed by researchers at UCL, Great Ormond Street Hospital, and the Wellcome Sanger Institute.

6 Jul 2023

The role of pulmonary dysfunction and COVID-19 severity in the development of Long COVID

Study identified a genome-wide significant association (GWAS) for long coronavirus disease.

6 Jul 2023

Vaping nicotine during pregnancy may be no safer for developing fetus than smoking cigarettes

Researchers at the University of Colorado Anschutz Medical Campus have found that vaping nicotine during pregnancy may be no safer for a developing fetus than smoking cigarettes.

5 Jul 2023

New protein found to help melanoma evade the immune system

New research from Sanford Burnham Prebys has helped explain how melanoma evades the immune system and may guide the discovery of future therapies for the disease.

5 Jul 2023

Study sheds light on cause of most common congenital heart defect

Bicuspid aortic valve is the most common congenital defect in humans, affecting between 1% and 2% of the population. Instead of the usual three symmetric leaflets, affected individuals have two asymmetric valve leaflets.

5 Jul 2023

Candidate genes for inflammatory bowel disease identified

A study of the genetic variation that makes mice more susceptible to bowel inflammation after a high-fat diet has identified candidate genes which may drive inflammatory bowel disease (IBD) in humans. The findings are published as a Reviewed Preprint in eLife.

5 Jul 2023

Fit to beat diabetes: mendelian randomization study confirms the power of exercise

Researchers investigated the causality of the relationship between cardiorespiratory fitness and diabetes mellitus type 2.

5 Jul 2023

Inherited genes linked to higher risk for diverticular disease of intestine

University of Queensland researchers have used genetics to reveal that much of the risk of developing a common and sometimes fatal intestinal disease is inherited.

4 Jul 2023

Spicing up rheumatic disease treatment: Study explores role of herbs and spices in improving patients' condition

Research explores the potential benefits of herbs and spices in rheumatic diseases, highlighting their bioactive compounds and medicinal properties. It provides an updated review of their mechanisms of action and summarizes human studies in Rheumatoid Arthritis, Osteoarthritis, and Fibromyalgia.

4 Jul 2023

Smoking and HPV found to increase risk of head and neck cancer

Tobacco smoking and human papillomavirus (HPV) are both well-known risk factors for head and neck cancer, but there is ample evidence to show they can interact to increase still further the risk of contracting the disease, according to a study by scientists at the University of São Paulo (USP) in Brazil and the University of Chile.

3 Jul 2023

Research establishes ERβ as a tumor suppressor in inflammatory breast cancer

A new editorial paper was published in Oncotarget's Volume 14 on June 12, 2023, entitled, "ERβ as a mediator of estrogen signaling in inflammatory breast cancer."

3 Jul 2023

Sugar sialic acid fuels disease-causing bacteria in the gut, study shows

A new study by researchers at the University of British Columbia (UBC) and BC Children's Hospital shows the sugar sialic acid, which makes up part of the protective intestinal mucus layer, fuels disease-causing bacteria in the gut.

3 Jul 2023

New study uncovers effects of beer compound on cartilage cells in osteoarthritis

Formononetin (FNT), an isoflavonoid present in beer, was investigated for its effects on chondrocytes, the cells responsible for joint health. While low levels of FNT showed no harm and reduced inflammation, excessive exposure promoted catabolic responses, shedding light on the relationship between beer consumption and osteoarthritis risk.

3 Jul 2023

AI predicts on- and off-target activity of RNA-targeting CRISPRs

Artificial intelligence can predict on- and off-target activity of CRISPR tools that target RNA instead of DNA, according to new research published in Nature Biotechnology.

3 Jul 2023

Base editing shows promise for treating sickle cell disease and beta thalassemia

Gene therapy that alters hemoglobin genes may be an answer to curing sickle cell disease (SCD) and beta thalassemia.

3 Jul 2023

SPG-15: A Mother's Fight for a Gene Therapy Cure, Maddi's Story

News Medical spoke to the CEO and founder of the Maddi Foundation to gain a patient perspective on how important research in gene therapy is.

3 Jul 2023

Insights gained from genetically modified pig heart transplantation

Researchers described a genetically engineered pig cardiac xenotransplantation in a 57-year-old male patient.

3 Jul 2023

Camena Bioscience closes $10m Series A financing as demand for DNA synthesis technology increases

Camena Bioscience, a synthetic biology company providing genes to the pharmaceutical and biotechnology industries.

From Camena Bioscience 3 Jul 2023

Inappropriate antibiotic use in low and middle-income countries disrupts infant gut health, fuels antimicrobial resistance

Overuse of antibiotics contributes to the problem of drug-resistant bacteria. Developing countries and young children are particularly affected. Review examines how antibiotics affect gut bacteria and drug resistance in infants in low- and middle-income countries.

2 Jul 2023

Combining proteomic and miRNA data yields superior age predictions, study suggests

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 12, entitled, "Age prediction from human blood plasma using proteomic and small RNA data: a comparative analysis."

30 Jun 2023

Genes News and Research

Study offers new insights into why some CAR T-cells persist in children with leukemia

The role of pulmonary dysfunction and COVID-19 severity in the development of Long COVID

Vaping nicotine during pregnancy may be no safer for developing fetus than smoking cigarettes

New protein found to help melanoma evade the immune system

Study sheds light on cause of most common congenital heart defect

Candidate genes for inflammatory bowel disease identified

Fit to beat diabetes: mendelian randomization study confirms the power of exercise

Inherited genes linked to higher risk for diverticular disease of intestine

Spicing up rheumatic disease treatment: Study explores role of herbs and spices in improving patients' condition

Smoking and HPV found to increase risk of head and neck cancer

Research establishes ERβ as a tumor suppressor in inflammatory breast cancer

Sugar sialic acid fuels disease-causing bacteria in the gut, study shows

New study uncovers effects of beer compound on cartilage cells in osteoarthritis

AI predicts on- and off-target activity of RNA-targeting CRISPRs

Base editing shows promise for treating sickle cell disease and beta thalassemia

SPG-15: A Mother's Fight for a Gene Therapy Cure, Maddi's Story

Insights gained from genetically modified pig heart transplantation

Camena Bioscience closes $10m Series A financing as demand for DNA synthesis technology increases

Inappropriate antibiotic use in low and middle-income countries disrupts infant gut health, fuels antimicrobial resistance

Combining proteomic and miRNA data yields superior age predictions, study suggests

eBook: Using iPSCs models for human disease research and drug discovery eBook

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