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YAP protein plays vital role in development of human neural crest

The Hippo/YAP signalling pathway plays a crucial role when the cells of the neural crest - a structure that generates cell types such as bones and nerve tissue - specialise for a certain function in the human embryo and migrate to their target region within the body.

22 Mar 2016

Women with Alzheimer’s disease have poorer cognitive abilities than men

Women with Alzheimer’s have poorer cognitive abilities than men at the same stage of the disease, reveal academics from the University of Hertfordshire in a paper published in World Journal of Psychiatry today.

22 Mar 2016

IUPUI investigators use stem cells to identify potential therapies to prevent glaucoma

Using stem cells derived from human skin cells, researchers led by Jason Meyer, assistant professor of biology, along with graduate student Sarah Ohlemacher of the School of Science at Indiana University-Purdue University Indianapolis, have successfully demonstrated the ability to turn stem cells into retinal ganglion cells (RGCs), the neurons that conduct visual information from the eye to the brain.

21 Mar 2016

New type of nerve cells appears to control feeding behaviors in mice

While researching the brain's learning and memory system, scientists at Johns Hopkins say they stumbled upon a new type of nerve cell that seems to control feeding behaviors in mice. The finding, they report, adds significant detail to the way brains tell animals when to stop eating and, if confirmed in humans, could lead to new tools for fighting obesity. Details of the study will be published by the journal Science on March 18.

20 Mar 2016

Brain's immune cells play direct role in development of amyotrophic lateral sclerosis

Cedars-Sinai research scientists have found that immune cells in the brain play a direct role in the development of amyotrophic lateral sclerosis, or ALS, offering hope for new therapies to target the neurodegenerative disease that gradually leads to paralysis and death.

18 Mar 2016

New scaffold technology could someday help treat Parkinson's disease, other brain-related conditions

Scientists at Rutgers and Stanford universities have created a new technology that could someday help treat Parkinson's disease and other devastating brain-related conditions that affect millions of people.

18 Mar 2016

Aesculap plans to develop neurostimulators for lowering high blood pressure

The Tuttlingen medical technology company Aesculap AG has founded the Freiburg startup neuroloop GmbH in cooperation with the University of Freiburg and the Freiburg University Medical Center. Building on research work from a team led by Prof. Dr. Thomas Stieglitz at the university's Department of Microsystems Engineering (IMTEK) and a research group at the university medical center, the company plans to develop neurostimulators that will be capable among other things of lowering high blood pressure.

18 Mar 2016

UW-Madison neuroscientist discover genetic machinery that causes maturation in young nerve cells

In one of the first studies to 'read' the genetic activity inside individual brain cells, University of Wisconsin-Madison neuroscientist Xinyu Zhao has identified the genetic machinery that causes maturation in a young nerve cell. The cells under study came from the hippocampus, a memory-related structure that is the only place in a mammal's brain where new neurons can form throughout life.

18 Mar 2016

Incidence of cesarean delivery could be reduced by allowing women to labor longer

When women in labor are given more time to deliver their baby than current guidelines recommend, their incidence of cesarean delivery drops by 55 percent, say researchers at Thomas Jefferson University.

17 Mar 2016

Mexican doctor develops prosthesis that provides sensations like natural hand

Thanks to the electrodes system a stable signal is obtained, which allows precise control like handling an egg without breaking. It also provides sensations as if it were a real hand.

16 Mar 2016

Kanazawa University researchers identify molecular mechanism that links liver disease and obesity

Kanazawa University researchers find similarities in the impeded signalling between central insulin activity and glucose production in the liver for both obese mice and mice that have had the vagus nerve removed.

16 Mar 2016

Omega-3 fatty acids improve cognitive function in older adults

Changes in cognitive function and memory decline form a normal part of aging. However, in neurodegenerative diseases such as Alzheimer's disease or mild cognitive impairment (the pre-dementia phase of Alzheimer's disease), these changes occur more quickly. There are currently no effective treatments for these diseases.

16 Mar 2016

Researchers provide new mechanism for age-related macular degeneration

Age-related macular degeneration (AMD) is the leading cause of visual impairment in people over 50 in developed countries. Although this condition affects up to 20% of people between the ages of 65 and 75, what drives abnormal blood vessels to invade the retina is unknown.

15 Mar 2016

Researchers identify new mutation responsible for spinocerebellar ataxia

Using the genetic information of two different families with three generations of disease, researchers have identified a new mutation responsible for a degenerative and ultimately fatal movement disorder. Through induced pluripotent stem cell techniques, researchers also grew neurons from one patient in the laboratory to be used in future experiments.

15 Mar 2016

Excessive fat accumulation in lower extremities of children linked to insulin resistance, metabolic disorders

Children with a severe type of spina bifida called myelomeningocele have a high prevalence of obesity and excess fat accumulation in their lower extremities. In a study designed to assess bone, muscle and fat tissue distribution in the lower legs of children with this disease, researchers at Children's Hospital Los Angeles determined that this excess fat tissue is within the muscle boundary (muscle-associated) rather than subcutaneous.

15 Mar 2016

Scientists find surprising link between iPS cell reprogramming, blood cell formation and cancer

The ability to reprogram cells has revolutionized stem cell research with major implications for almost all fields of modern biology. A decade ago Shinya Yamanaka described a procedure that revolutionized stem cell biology. Using a genetic trick that introduces a cocktail of four genes into cultured cells from human biopsies, he was able to generate induced pluripotent stem cells (iPS) from mature skin or blood cells

15 Mar 2016

Anticancer drug restores hearing in neurofibromatosis patients

In a small clinical study with an anticancer drug that halts blood vessel growth, a handful of people with neurofibromatosis type 2 (NF2) and hearing loss had restoration of hearing.

15 Mar 2016

Researchers identify potential drug target in skin for itchy feeling

No matter the trigger -- bug bites, a medication side-effect or an itchy wound -- the urge to scratch can be a real pain. Researchers at the Duke University Medical Center have identified a potential drug target in the skin for that itchy feeling.

14 Mar 2016

Neurofeedback decreases pain, increases quality of life in patients with neuropathic pain

A new study from The University of Texas MD Anderson Cancer Center evaluating the use of neurofeedback found a decrease in the experience of chronic pain and increase quality of life in patients with neuropathic pain.

14 Mar 2016

TRPV2 could be a target for obesity therapy

Brown adipose tissue (BAT), a major site for mammalian non-shivering thermogenesis, could be a target for prevention and treatment of human obesity. Transient receptor potential vanilloid 2 (TRPV2), a Ca2+-permeable cation channel, plays vital roles in the regulation of various cellular functions.

14 Mar 2016

Nerve News and Research

YAP protein plays vital role in development of human neural crest

Women with Alzheimer’s disease have poorer cognitive abilities than men

IUPUI investigators use stem cells to identify potential therapies to prevent glaucoma

New type of nerve cells appears to control feeding behaviors in mice

Brain's immune cells play direct role in development of amyotrophic lateral sclerosis

New scaffold technology could someday help treat Parkinson's disease, other brain-related conditions

Aesculap plans to develop neurostimulators for lowering high blood pressure

UW-Madison neuroscientist discover genetic machinery that causes maturation in young nerve cells

Incidence of cesarean delivery could be reduced by allowing women to labor longer

Mexican doctor develops prosthesis that provides sensations like natural hand

Kanazawa University researchers identify molecular mechanism that links liver disease and obesity

Omega-3 fatty acids improve cognitive function in older adults

Researchers provide new mechanism for age-related macular degeneration

Researchers identify new mutation responsible for spinocerebellar ataxia

Excessive fat accumulation in lower extremities of children linked to insulin resistance, metabolic disorders

Scientists find surprising link between iPS cell reprogramming, blood cell formation and cancer

Anticancer drug restores hearing in neurofibromatosis patients

Researchers identify potential drug target in skin for itchy feeling

Neurofeedback decreases pain, increases quality of life in patients with neuropathic pain

TRPV2 could be a target for obesity therapy

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