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BioCryst starts BCX4161 Phase 1 clinical trial for treatment of hereditary angioedema

BioCryst Pharmaceuticals, Inc. announced the initiation of a Phase 1 clinical trial to evaluate the safety, pharmacokinetics and pharmacodynamics of orally-administered BCX4161 in healthy volunteers.

25 Mar 2013

Researchers study how nerve cells repair themselves after injury

One molecule makes nerve cells grow longer. Another one makes them grow branches. These new experimental manipulations have taken researchers a step closer to understanding how nerve cells are repaired at their farthest reaches after injury.

25 Mar 2013

Combination of HUCBCs and Simvastatin offers promising therapy for stroke: Study

Researchers at the Henry Ford Health System (Detroit, MI) and colleagues at Saneron CCEL Therapeutics, Inc. of Tampa, Florida, have found that when human umbilical cord blood cells were transplanted into test rats modeled with stroke, the addition of Simvastatin to the HUCBCs significantly increased the therapeutic benefit of the HUCBCs.

21 Mar 2013

Illinois chemists use DNA catalysts to do protein's job

Illinois chemists have used DNA to do a protein's job, creating opportunities for DNA to find work in more areas of biology, chemistry and medicine than ever before.

20 Mar 2013

Federal judge strikes Mo. law exempting some from health law's birth control mandate

A federal judge has ruled that a Missouri law exempting moral objectors from the health law's mandate on birth control coverage cannot stand.

20 Mar 2013

New research project on systems biology of synapse proteins and ageing launched

The AgedBrainSYSBIO project on systems biology of synapse proteins & ageing was officially launched March18th in Paris, France.

20 Mar 2013

First Edition: March 19, 2013

Today's headlines include coverage of a new report about the troubling reach of Alzheimer's disease.

19 Mar 2013

Nanomix announces allowance of patent application for carbon nanotube technology

Nanomix Inc., a leading nanotechnology company focused on development of next generation point of care diagnostic tests to enable earlier and more accurate testing in hospital and pre-hospital settings, announced today that the United States Patent and Trademark Office has allowed a patent application relating to flexible nanostructure electronic devices, such as nanotube sensors and transistors, and method for fabricating the same.

19 Mar 2013

Study identifies genetic cause of developmental delay in Amish individuals in USA

Researchers from the research group in growth factors and cell differentiation at the University of Barcelona (UB) and the IDIBELL and have participated in an international study that has identified the genetic cause of developmental delay observed in Amish individuals in the USA.

15 Mar 2013

Study demonstrates relationship between protein HERC2 and human diseases

Researchers from the research group in growth factors and cell differentiation at IDIBELL and the University of Barcelonahave participated in an international study that has identified the genetic cause of developmental delay observed in Amish individuals in the USA.

13 Mar 2013

Anti-cancer drug conjugates: an interview with Dr Andreas Menrad, CSO Ablynx and Dr Chris Martin, CEO Spirogen

Antibodies and in the case of Ablynx, Nanobodies, can be raised and selected to bind with high affinity selectively to cancer cells in a tumour. Cancer cells are exquisitely sensitive to certain toxins such as the PBDs produced by Spirogen.

12 Mar 2013

Scientists develop new method for replacing missing teeth

Scientists have developed a new method of replacing missing teeth with a bioengineered material generated from a person's own gum cells.

11 Mar 2013

Scientists discover key biochemical step underlying heart failure

Some 5.8 million Americans suffer from heart failure, a currently incurable disease. But scientists at Temple University School of Medicine's (TUSM) Center for Translational Medicine have discovered a key biochemical step underlying the condition that could aid the development of new drugs to treat and possibly prevent it.

6 Mar 2013

Scientists discover enzyme regulation that catalyzes chain elongation in the terpenoid pathway

Max Planck scientists in Jena, Germany, have discovered an unusual regulation of enzymes that catalyze chain elongation in an important secondary metabolism, the terpenoid pathway.

2 Mar 2013

Stem cell line could also advance research into liver cancers, cystic fibrosis

Chronic or acute, liver failure can be deadly. Toxins take over, the skin turns yellow and higher brain function slows. "There is no effective therapy at the moment to deal with the toxins that build up in your body," said Neil Talbot, a Research Animal Scientist for the USDA Agricultural Research Service. "Their only option now is to transplant a liver."

1 Mar 2013

Wyss Founding Director receives NC3Rs 3Rs Prize for Lung-on-a-Chip

In a London ceremony today, Wyss Founding Director Don Ingber, M.D., Ph.D., received the NC3Rs 3Rs Prize from the UK's National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) for his innovative Lung-on-a-Chip -- a microdevice lined by human cells that recapitulates complex functions of the living lung.

28 Feb 2013

IFR, PBL to further develop Dynamic Gastric Model

The Dynamic Gastric Model, developed from years of research at the Institute of Food Research, has taken significant steps towards improving its commercial use by food and drug companies worldwide.

26 Feb 2013

Wnt-induced Lgr5 expression marks stem cell production in the liver

For decades scientists around the world have attempted to regenerate primary liver cells known as hepatocytes because of their numerous biomedical applications, including hepatitis research, drug metabolism and toxicity studies, as well as transplantation for cirrhosis and other chronic liver conditions. But no lab in the world has been successful in identifying and growing liver stem cells in culture -- using any available technique - until now.

26 Feb 2013

Study finds major risk factor behind increased risk of adverse outcomes in IVF pregnancies

Massachusetts General Hospital (MGH) researchers have identified what may be a major factor behind the increased risk of two adverse outcomes in pregnancies conceived through in vitro fertilization (IVF).

26 Feb 2013

Mindray fourth quarter net revenues increase 19.7% to $316.1 million

Mindray Medical International Limited, a leading developer, manufacturer and marketer of medical devices worldwide, announced today its selected unaudited financial results for the fourth quarter and full year ended December 31, 2012.

From Mindray 25 Feb 2013

in vitro News and Research

BioCryst starts BCX4161 Phase 1 clinical trial for treatment of hereditary angioedema

Researchers study how nerve cells repair themselves after injury

Combination of HUCBCs and Simvastatin offers promising therapy for stroke: Study

Illinois chemists use DNA catalysts to do protein's job

Federal judge strikes Mo. law exempting some from health law's birth control mandate

New research project on systems biology of synapse proteins and ageing launched

First Edition: March 19, 2013

Nanomix announces allowance of patent application for carbon nanotube technology

Study identifies genetic cause of developmental delay in Amish individuals in USA

Study demonstrates relationship between protein HERC2 and human diseases

Anti-cancer drug conjugates: an interview with Dr Andreas Menrad, CSO Ablynx and Dr Chris Martin, CEO Spirogen

Scientists develop new method for replacing missing teeth

Scientists discover key biochemical step underlying heart failure

Scientists discover enzyme regulation that catalyzes chain elongation in the terpenoid pathway

Stem cell line could also advance research into liver cancers, cystic fibrosis

Wyss Founding Director receives NC3Rs 3Rs Prize for Lung-on-a-Chip

IFR, PBL to further develop Dynamic Gastric Model

Wnt-induced Lgr5 expression marks stem cell production in the liver

Study finds major risk factor behind increased risk of adverse outcomes in IVF pregnancies

Mindray fourth quarter net revenues increase 19.7% to $316.1 million

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Why use light scattering to analyze proteins and viral vectors?

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