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Novel method stimulates growth of new neurons in adult brain

University at Buffalo researchers have identified a new mechanism that plays a central role in adult brain stem cell development and prompts brain stem cells to differentiate into neurons.

21 May 2009

Study offers new insights into morphine-induced tolerance and increased pain sensitivity

A study published in the June issue of Anesthesiology has shown that a drug metabolite of the opioid morphine may be a key factor in the paradoxical increased sensitivity to pain caused by chronic morphine use. For the first time, this metabolite (called morphine-6 glucuronide, or M6G) was shown to act independently of the pain receptors typically targeted during morphine administration.

21 May 2009

Robotic therapy for cerebral palsy

Over the past few years, MIT engineers have successfully tested robotic devices to help stroke patients learn to control their arms and legs. Now, they're building on that work to help children with cerebral palsy.

20 May 2009

People with Down syndrome may have more cancer-protective genes

Most cancers are rare in people with Down syndrome, whose overall cancer mortality is below 10 percent of that in the general population. Since they have an extra copy of chromosome 21, it's been proposed that people with Down syndrome may be getting an extra dose of one or more cancer-protective genes.

20 May 2009

Methylene blue in combo with new malaria drugs curbs the spread of malaria parasites

New combinations of agents based on the oldest synthetic malaria drug, the methylene blue stain, can curb the spread of malaria parasites and make a significant contribution to the long-term eradication called for by the international "Roll Back Malaria Initiative."

20 May 2009

Vitamin D may halt lung function decline in asthma and COPD

Vitamin D may slow the progressive decline in the ability to breathe that can occur in people with asthma as a result of human airway smooth muscle (HASM) proliferation, according to researchers at the University of Pennsylvania.

20 May 2009

Nanoparticles used to stimulate growth of new neurons in adult brain

University at Buffalo researchers have identified a new mechanism that plays a central role in adult brain stem cell development and prompts brain stem cells to differentiate into neurons.

20 May 2009

NIH to develop therapeutics for rare and neglected diseases

The National Institutes of Health is launching the first integrated, drug development pipeline to produce new treatments for rare and neglected diseases. The $24 million program jumpstarts a trans-NIH initiative called the Therapeutics for Rare and Neglected Diseases program, or TRND.

20 May 2009

Discovery of proteins underlying devastating brain diseases

Scientists at the Wellcome Trust Sanger Institute have discovered a set of brain proteins responsible for some of the most common and devastating brain diseases.

19 May 2009

Adult stem cells from bone marrow can deliver cancer-killing proteins to tumors

Researchers in London have demonstrated the ability of adult stem cells from bone marrow (mesenchymal stem cells, or MSCs) to deliver a cancer-killing protein to tumors.

19 May 2009

Genetic signature predicts clinical outcomes in certain types of breast cancer

Vanderbilt-Ingram Cancer Center researchers have uncovered a gene signature that may help predict clinical outcomes in certain types of breast cancer.

19 May 2009

Protein neuregulin 1 critical to insulating the body's wiring could also become treatment target

A new protein identified as critical to insulating the wiring that connects the brain and body could one day be a treatment target for divergent diseases, from rare ones that lower the pain threshold to cancer, Medical College of Georgia researchers say.

19 May 2009

HRT-breast cancer risk stays same, regardless of family history

The risk of developing breast cancer due to taking hormone replacement therapy appears to be the same for women with a family history of the disease and without a family history, a University of Rochester Medical Center study concluded.

19 May 2009

New asthma treatment bronchial thermoplasty improves patient quality of life

Chronic asthma sufferers may find new relief in a simple, minimally invasive outpatient procedure known as bronchial thermoplasty, which uses controlled radiofrequency-generated heat to treat the muscles of the airways, preventing them from constricting and narrowing.

18 May 2009

Trace elements unbalanced in dialysis patients

Abnormal levels of trace elements may explain dialysis morbidity. A systematic review published in the open access journal BMC Medicine has shown that, compared to healthy controls, dialysis patients have significantly different blood concentrations of trace elements.

18 May 2009

California mental health advocates raise concern over treatment of ICE detainees

The San Diego Tribune on Monday profiled the La Mesa, Calif.-based private psychiatric hospital Alvarado Parkway Institute. Some advocates say that the hospital is in a network of private hospitals that U.S. Immigration and Customs Enforcement uses to hold "severely" mentally ill detainees nationwide, often "out of reach of lawyers and even their families," the Tribune reports.

18 May 2009

Many low-income women breast cancer patients skipping hormonal therapy, lowering their survival rates

Many low-income women are failing to take the hormonal therapy prescribed as part of their breast cancer treatment, possibly lowering their survival rates, according to a study led by a researcher in the Duke Comprehensive Cancer Center.

18 May 2009

Study looks at transpalatal advancement pharyngoplasty procedure for sleep apnea

Treatment with surgery or an oral appliance that adjusts the jaw is associated with improvements in obstructive sleep apnea, a condition caused by blocked upper airways in which patients periodically stop breathing during sleep, according to two reports in the May issue of Archives of Otolaryngology–Head & Neck Surgery.

18 May 2009

Early mobilization of patients in intensive care improves outcomes

Aside from the obvious and immediate health problems that patients undergoing mechanical ventilation face, those who recover often do so with profound loss of strength and mobility that can impair their daily functioning and even lead to increased risk of morbidity and mortality down the line.

17 May 2009

Self-treatment lowers overall health care costs for chronic obstructive pulmonary disorder sufferers

Individuals suffering from chronic obstructive pulmonary disorder (COPD) can experience significant savings in healthcare costs by employing a self-treatment program with the judicious use of medications, according to the results of a new study. The self-treatment program achieves these savings by reducing the duration of flare-ups.

17 May 2009

Therapy News and Research

Novel method stimulates growth of new neurons in adult brain

Study offers new insights into morphine-induced tolerance and increased pain sensitivity

Robotic therapy for cerebral palsy

People with Down syndrome may have more cancer-protective genes

Methylene blue in combo with new malaria drugs curbs the spread of malaria parasites

Vitamin D may halt lung function decline in asthma and COPD

Nanoparticles used to stimulate growth of new neurons in adult brain

NIH to develop therapeutics for rare and neglected diseases

Discovery of proteins underlying devastating brain diseases

Adult stem cells from bone marrow can deliver cancer-killing proteins to tumors

Genetic signature predicts clinical outcomes in certain types of breast cancer

Protein neuregulin 1 critical to insulating the body's wiring could also become treatment target

HRT-breast cancer risk stays same, regardless of family history

New asthma treatment bronchial thermoplasty improves patient quality of life

Trace elements unbalanced in dialysis patients

California mental health advocates raise concern over treatment of ICE detainees

Many low-income women breast cancer patients skipping hormonal therapy, lowering their survival rates

Study looks at transpalatal advancement pharyngoplasty procedure for sleep apnea

Early mobilization of patients in intensive care improves outcomes

Self-treatment lowers overall health care costs for chronic obstructive pulmonary disorder sufferers

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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