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Schering-Plough's investigational oral thrombin receptor antagonist meets primary endpoint in a newly published study

Results of a Schering-Plough Corporation Phase II trial of SCH 530348, a novel oral thrombin receptor antagonist (TRA), were published today in The Lancet and demonstrated that the investigational antiplatelet compound met its primary endpoints of safety and tolerability.

12 Mar 2009

New drug derived from magnolia trees proves safe, tolerable in preventing blood clots

A new drug derived from magnolia trees appears to be able to uncouple two important functions of thrombin in blood clot formation and may offer a way to better control the potentially dangerous complications of bleeding and clot formation during procedures to open blocked coronary arteries, say researchers at the Duke Clinical Research Institute (DCRI).

12 Mar 2009

Interventional radiology makes complicated C-sections safer

Innovative, interventional radiology treatments are making childbirth safer for women who have C-sections that are complicated by massive bleeding and for those who suffer from the pregnancy condition of "invasive" placenta.

11 Mar 2009

Diagnostic errors: The new focus of patient safety experts

Johns Hopkins patient safety experts say it's high time for diagnostic errors to get the same attention from medical institutions and caregivers as drug-prescribing errors, wrong-site surgeries and hospital-acquired infections.

11 Mar 2009

How to avoid colon problems

Most adults would rather keep talk about colons behind the bathroom door.It's time to talk, says Kim Turgeon, MD, FACP, gastroenterologist in Internal Medicine at the University of Michigan Health System.

10 Mar 2009

Sonohysterography is an alternative diagnostic tool for women with adenomyosis

Sonohysterography (SHG), a simple ultrasound technique commonly used to evaluate the uterine cavity, improves the diagnostic capability of transvaginal ultrasound in detecting adenomyosis (a common benign condition of the uterus that causes dysmenorrhea, abnormal vaginal bleeding and pelvic pain), according to a study performed at the Thomas Jefferson University Hospital in Philadelphia, PA.

4 Mar 2009

Colonoscopy and virtual colonoscopy, either way get screened!

Today, patients have a wide selection of colorectal cancer screening exams from which to choose, unlike with other types of cancers.

3 Mar 2009

Certain combined medications after heart attack may increase risk of death

Following an acute coronary syndrome such as a heart attack or unstable angina, patients who receive a medication to reduce the risk of gastrointestinal bleeding that may be associated with the use of the antiplatelet drug clopidogrel and aspirin have an increased risk of subsequent hospitalization for acute coronary syndrome or death, according to a study in the March 4 issue of JAMA, the Journal of the American Medical Association.

3 Mar 2009

Bionovo announces publication of positive trial results for Menerba

Bionovo, Inc. has announced the online publication of a peer-reviewed article in the journal, Menopause, reporting Menerba (formerly MF101) is well tolerated, safe and effective for the treatment of vasomotor symptoms (hot flashes and night sweats) associated with menopause.

3 Mar 2009

Drinking one glass of wine a day may lower risk of Barrett's esophagus

Drinking one glass of wine a day may lower the risk of Barrett's Esophagus by 56 percent, according to a new study by the Kaiser Permanente Division of Research in the March issue of Gastroenterology.

2 Mar 2009

Drinking wine may lower risk of Barrett's esophagus

2 Mar 2009

Study examines maternal and newborn health risks and colorectal cancer

In one of the first studies to examine maternal and newborn health risks and colorectal cancer, UC Davis researchers have found that women diagnosed with the disease during or shortly after their pregnancies have the same survival as women who have the disease and are not pregnant.

26 Feb 2009

Experimental animal vaccine may protect humans from Ebola

Protection against Ebola, one of the world's deadliest viruses, can be achieved by a vaccine produced in insect cells, raising prospects for developing an effective vaccine for humans, say scientists at the Southwest Foundation for Biomedical Research (SFBR) in San Antonio.

26 Feb 2009

Increasing number of women suffer from post-birth bleeding

Post-partum haemorrhage (PPH) immediately after giving birth is the largest threat to new mothers in high-income countries.

25 Feb 2009

Genital piercings can cause serious health complications

While men can rely on that little, blue pill to improve things in the bedroom, women are turning to more extreme measures to enhance sexual intercourse.

25 Feb 2009

Stroke treated significantly faster and just as safely by medical residents

Diagnosing acute stroke is a high-pressure decision. The speed with which treatment is delivered makes all the difference. Early treatment can stop brain damage, but if treatment is given inappropriately, it can dangerously increase the risk of bleeding in the brain.

24 Feb 2009

Researchers block immune cell rush behind deadly sepsis

Researchers have found a way to block the ability of white blood cells to sprint toward the sites of infection when such speed worsens the damage done by sepsis, the often fatal, whole-body bacterial infection, according to a study published today in the journal Blood.

24 Feb 2009

Aneurysms do not occur earlier in second generation

People whose parents or aunts and uncles have had a brain aneurysm are more likely to have one themselves, indicating that genetic risk factors passed down by generation are responsible.

23 Feb 2009

Kidney disease affects response to anticoagulant drug warfarin

Patients with reduced kidney function require lower doses of the anticoagulant drug warfarin, and may need closer monitoring to avoid serious bleeding complications, suggests a study in the April 2009 issue of the Journal of the American Society of Nephrology ( JASN ).

20 Feb 2009

Optimizing dosage of blood-thinning drug warfarin

In a large-scale study and an upcoming clinical trial, scientists supported by the National Institutes of Health address one of the trickiest issues in prescribing medicine - how to quickly optimize each patient's dosage of the common blood-thinning drug warfarin.

20 Feb 2009