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New nanosensing technique enhances quality control for gene therapy vectors

Over the past few decades, there has been remarkable progress in genetic manipulation technologies, bringing us closer to the point where genes can be modified in vivo.

1 Aug 2024

Study reveals how geographic origins influence tuberculosis infection risk

For some forms of tuberculosis, the chances that an exposed person will get infected depend on whether the individual and the bacteria share a hometown, according to a new study comparing how different strains move through mixed populations in cosmopolitan cities.

1 Aug 2024

Higher urinary metal levels linked to increased cardiovascular risk

Higher levels of urinary metals such as cadmium, tungsten, uranium, cobalt, copper and zinc are linked to increased cardiovascular disease and mortality in a racially and ethnically diverse U.S. population, according to a new study at Columbia University Mailman School of Public Health.

1 Aug 2024

Targeting 14 modifiable risk factors from childhood to old age could prevent or delay dementia

Addressing 14 modifiable risk factors, starting in childhood and continuing throughout life, could prevent or delay nearly half of dementia cases, even as people around the world live longer and the number of people with dementia is set to rise dramatically in all countries, according to the third Lancet Commission on dementia prevention, intervention, and care, which is being presented at the Alzheimer's Association International Conference (AAIC 2024).

1 Aug 2024

AI reprograms glioblastoma cells into dendritic cells for cancer immunotherapy

In an innovative new study of glioblastoma, scientists used artificial intelligence (AI) to reprogram cancer cells, converting them into dendritic cells (DCs), which can identify cancer cells and direct other immune cells to kill them.

31 Jul 2024

FDA clears UAB startup's TIX100 for clinical trials

The University of Alabama at Birmingham startup TIXiMED, Inc., has obtained clearance from the United States Food and Drug Administration to proceed to clinical trials under an Investigational New Drug for TIX100, its novel oral Type 1 diabetes drug.

31 Jul 2024

Advanced technology and AI used to diagnose rare diseases and birth abnormalities

Researchers at London Health Sciences Centre (LHSC) and Lawson Health Research Institute are using advanced technology and artificial intelligence (AI) to diagnose rare diseases and prenatal exposure-related birth abnormalities in two studies published today in American Journal of Human Genetics and Genetics in Medicine.

31 Jul 2024

Vegan diet may slow aging

Vegan diets showed short-term benefits on epigenetic aging compared to omnivorous diets in healthy twins, with reduced epigenetic age metrics observed in the vegan group. However, telomere length and overall mitotic clock values remained unchanged for both diets.

31 Jul 2024

From Waste to Taste: The Transformative Power of Fermented Foods

In this interview conducted at Pittcon 2024 in San Diego, Maria Marco discusses her research on the health benefits, safety, and waste reduction potential of fermented foods, and the microbial processes involved in their production.

From Pittcon 31 Jul 2024

Asimov introduces its AI-driven 4th generation CHO Edge System with increased titer guarantee

Asimov, the synthetic biology company advancing the design and manufacture of therapeutics, today announced the launch of its fourth generation CHO Edge System.

From Asimov 31 Jul 2024

Penn researchers find a way to tease apart genetic and environmental effects of disease risk

Every disease is shaped by a genetic component as well as environmental factors like air pollution, climate and socioeconomic status.

30 Jul 2024

Genetic loss of miR-205 boosts mammary gland development in mice, reveals new insights into breast cancer suppression

Genetic loss of miR-205 in mice enhances mammary gland development and branching, challenging previous lethality findings and highlighting its onco-suppressive functions.

30 Jul 2024

Researchers identify key genetic variants linked to ALS recovery

Though exceedingly rare, some people diagnosed with amyotrophic lateral sclerosis (ALS) partially or fully recover from the lethal neurodegenerative disease.

30 Jul 2024

Targeting oncogenic transcription factors to develop potential new cancer treatments

A new study from the University of Michigan Health Rogel Cancer Center furthers research that suggests the potential of developing new cancer treatments to target oncogenic transcription factors by indirectly affecting their ability to access enhancer DNA in chromatin.

30 Jul 2024

Applied Microbiology International strengthens network with 11 new Global Ambassadors

Applied Microbiology International has announced that it has recruited 11 new Global Ambassadors from around the world.

30 Jul 2024

Epigenetic reprogramming and hypothalamic changes in metabolic syndrome

Metabolic syndrome (MetS) is a multifaceted disorder that impacts approximately 20–25% of the global population.

30 Jul 2024

Study finds higher levels of lncRNAs in the testes than previously estimated

Researchers at the University of Toronto have mapped the spatial distribution of around 700 long non-coding RNAs, otherwise known as lncRNAs, in the testes.

30 Jul 2024

Dementia risk rises with elevated remnant cholesterol, South Korean study reveals

How remnant cholesterol (remnant-C) levels are associated with the risk of developing dementia using a large dataset from South Korea.

30 Jul 2024

Genetic variants associated with Parkinson's more common than estimated

New research has found that genetic variants associated with Parkinson's disease (PD) are more common than researchers previously believed. Investigators in the Parkinson's Foundation-backed PD GENEration study – which reached its goal of 15,000 participants ahead of schedule this spring – found that 13% of participants have a genetic form of PD, which is a significant observation compared to long-standing estimates. Results from the first 3.5 years of the study, which examined a broad North American cohort, were published in the peer-reviewed scientific journal Brain.

30 Jul 2024

Transthyretin protein levels linked to heart failure and mortality

Physician-scientists from the University of Alabama at Birmingham Marnix E. Heersink School of Medicine have uncovered significant findings regarding the impact of transthyretin, or TTR, protein levels on heart disease risk.

29 Jul 2024

Genetic News and Research

New nanosensing technique enhances quality control for gene therapy vectors

Study reveals how geographic origins influence tuberculosis infection risk

Higher urinary metal levels linked to increased cardiovascular risk

Targeting 14 modifiable risk factors from childhood to old age could prevent or delay dementia

AI reprograms glioblastoma cells into dendritic cells for cancer immunotherapy

FDA clears UAB startup's TIX100 for clinical trials

Advanced technology and AI used to diagnose rare diseases and birth abnormalities

Vegan diet may slow aging

From Waste to Taste: The Transformative Power of Fermented Foods

Asimov introduces its AI-driven 4th generation CHO Edge System with increased titer guarantee

Penn researchers find a way to tease apart genetic and environmental effects of disease risk

Genetic loss of miR-205 boosts mammary gland development in mice, reveals new insights into breast cancer suppression

Researchers identify key genetic variants linked to ALS recovery

Targeting oncogenic transcription factors to develop potential new cancer treatments

Applied Microbiology International strengthens network with 11 new Global Ambassadors

Epigenetic reprogramming and hypothalamic changes in metabolic syndrome

Study finds higher levels of lncRNAs in the testes than previously estimated

Dementia risk rises with elevated remnant cholesterol, South Korean study reveals

Genetic variants associated with Parkinson's more common than estimated

Transthyretin protein levels linked to heart failure and mortality

eBook: Using iPSCs models for human disease research and drug discovery eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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