Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Inhibition of RANK signaling pathway could be potential new therapy in breast cancer

Researchers at the Institute of Biomedical Research of Bellvitge, led by Dr. Eva Gonzalez-Suarez, have shown that pharmacological and genetic inhibition of signaling pathway RANK / RANKL leads to a significant reduction in recurrences and metastases in breast cancer in a mouse animal model.

13 Sep 2016

Novel DNA-altering method could lead to more treatment options for diseases

Researchers in Singapore have developed a new protein that can alter DNA in living cells with much higher precision than current methods.

13 Sep 2016

Isolation of human NP cells may offer way to foster renal regeneration after chronic kidney failure

In a first-of-its-kind look at human kidney development, researchers at The Saban Research Institute of Children's Hospital Los Angeles have isolated human nephron progenitor (NP) cells.

12 Sep 2016

Study reveals promising strategy against bladder cancer metastasis

The popular kids' card game "Exploding Kittens" teaches a concept critical to cancer science: When a player plays a "Nope" card, the subsequent player may lay another "Nope", thus creating a double-negative that becomes a positive, allowing the initial action to proceed.

12 Sep 2016

UTHealth receives DOD award to investigate stem cell therapy in adults with TBI

A research team led by Charles S. Cox, Jr., M.D., at The University of Texas Health Science Center at Houston has been awarded $6.8 million from the U.S. Department of Defense to assess the safety and efficacy of using autologous stem cell therapy in adults with emergent traumatic brain injury.

9 Sep 2016

Scientists reveal underlying mechanisms leading to microcephaly in NBS patients

Scientists from Jerusalem and Duesseldorf have succeeded in generating induced pluripotent stem cells from a rare disorder called Nijmegen breakage syndrome (NBS) and to push these cells to become early neurons, revealing the mechanisms leading to the neurological phenotype observed in these patients.

9 Sep 2016

Stem cells may be responsible for vascular calcification in patients with kidney disease

Scientists have implicated a type of stem cell in the calcification of blood vessels that is common in patients with chronic kidney disease.

8 Sep 2016

TKCI pioneers new treatment techniques for patients suffering from Stevens-Johnson syndrome

The Tej Kohli Cornea Institute, in partnership with the world-renowned LV Prasad Eye Institute in Hyderabad, is pioneering new treatments for sufferers of Stevens-Johnson syndrome (SJS), which takes the lives of 20%-25% of the people it affects.

8 Sep 2016

Study finds cord blood transplant recipients appear to have better outcomes against leukemia

Umbilical cord blood transplants may have advantages beyond offering an alternative stem cell source for leukemia patients without a traditional donor match, according to a study published today in The New England Journal of Medicine.

8 Sep 2016

TUM researchers use luminous jellyfish proteins to investigate cardiac rhythm dysfunctions

Cell models from stem cells serve an ever-increasing role in research of cardiac dysfunction. Researchers at the Technical University of Munich have succeeded in producing cells which offer new insights into properties of the heart.

6 Sep 2016

Researchers identify epigenetic mechanism causing aberrancies in coeliac disease

Researchers at the University of Tampere discovered a mechanism causing aberrancies in coeliac disease and colorectal cancer.

5 Sep 2016

New collaborative initiative to develop novel ways of screening drugs for bipolar disorder, schizophrenia

The Johns Hopkins University School of Medicine and the Salk Institute for Biological Studies will co-lead a $15.4 million effort to develop new systems for quickly screening libraries of drugs for potential effectiveness against schizophrenia and bipolar disorder, the National Institute of Mental Health (NIMH) has announced.

2 Sep 2016

Six NIH-funded projects aim to identify biological factors that affect neural regeneration

The National Institutes of Health will fund six projects to identify biological factors that affect neural regeneration in the retina.

2 Sep 2016

Blood cancer treatment linked to distinct increase in molecular age of immune cells

Certain cancer treatments are known to take a toll on patients, causing side effects like fatigue, nausea and hair loss. Now, scientists are investigating whether some treatments can cause another long-term side effect: premature aging of important disease-fighting cells.

1 Sep 2016

Texas Tech researcher examines how healthy brown fat can be activated in humans

Come fall, being a bear starts to look better and better. They load up on fat, sleep the winter away and wake up hungry.

1 Sep 2016

Research sheds new light on how human organ systems develop

For the first time, the precise way individual human organs and tissue develop has been mapped - providing new insight into how genetic disorders can occur during the crucial early phase of development.

1 Sep 2016

Common signaling pathway may control formation of tumor cells in fat, reveals Purdue study

A common cell signaling pathway that controls differentiation of stem cells may also control the formation of tumor cells in fat, according to a Purdue University study.

31 Aug 2016

Scientists generate functional tissue-engineered liver from adult stem and progenitor cells

A research team led by investigators at The Saban Research Institute of Children's Hospital Los Angeles has generated functional human and mouse tissue-engineered liver from adult stem and progenitor cells.

31 Aug 2016

New stem-cell model of heart tissue unravels mechanisms linked to hypertrophic cardiomyopathy

Using advanced stem cell technology, scientists from the Icahn School of Medicine at Mount Sinai have created a model of a heart condition called hypertrophic cardiomyopathy (HCM) — an excessive thickening of the heart that is associated with a number of rare and common illnesses, some of which have a strong genetic component.

31 Aug 2016

Transplantation of placenta-derived MSCs can prevent diabetes-related CLI in rats

In an effort to determine if stem cell therapy can prevent or improve a condition called "diabetic foot" caused by poor blood flow in patients with diabetes, a team of researchers in China has found that transplanting human placenta-derived mesenchymal stem cells (MSCs) into rats modeled with diabetes can affect blood vessel growth, potentially improving blood flow and preventing critical limb ischemia (CLI), a condition that results in diabetic foot and frequently leads to amputation.

30 Aug 2016

Stem Cells News and Research

Further Reading

Inhibition of RANK signaling pathway could be potential new therapy in breast cancer

Novel DNA-altering method could lead to more treatment options for diseases

Isolation of human NP cells may offer way to foster renal regeneration after chronic kidney failure

Study reveals promising strategy against bladder cancer metastasis

UTHealth receives DOD award to investigate stem cell therapy in adults with TBI

Scientists reveal underlying mechanisms leading to microcephaly in NBS patients

Stem cells may be responsible for vascular calcification in patients with kidney disease

TKCI pioneers new treatment techniques for patients suffering from Stevens-Johnson syndrome

Study finds cord blood transplant recipients appear to have better outcomes against leukemia

TUM researchers use luminous jellyfish proteins to investigate cardiac rhythm dysfunctions

Researchers identify epigenetic mechanism causing aberrancies in coeliac disease

New collaborative initiative to develop novel ways of screening drugs for bipolar disorder, schizophrenia

Six NIH-funded projects aim to identify biological factors that affect neural regeneration

Blood cancer treatment linked to distinct increase in molecular age of immune cells

Texas Tech researcher examines how healthy brown fat can be activated in humans

Research sheds new light on how human organ systems develop

Common signaling pathway may control formation of tumor cells in fat, reveals Purdue study

Scientists generate functional tissue-engineered liver from adult stem and progenitor cells

New stem-cell model of heart tissue unravels mechanisms linked to hypertrophic cardiomyopathy

Transplantation of placenta-derived MSCs can prevent diabetes-related CLI in rats

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