Therapy News and Research

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Trial of Quadramet (153 Samarium-lexidronam) in combo with Velcade shows positive results

Quadramet (153 Samarium-lexidronam) is a radioactive medication that targets the bone, specifically bone cancer, and is used to treat pain caused by cancer that has metastasized or spread to the bone.

15 Feb 2009

Candesartan cilexetil reduces proteinuria in kidney disease patients

Taking a much higher than recommended dose of the hypertension drug candesartan cilexetil effectively lowered the amount of protein excreted in the urine of patients with kidney disease, according to a study appearing in the April 2009 issue of the Journal of the American Society Nephrology ( JASN ).

11 Feb 2009

Discovery of new mechanism that tumours use to stimulate growth of blood vessels that feed them

The development of cancerous tumours is highly dependent on the nutrients the tumours receive through the blood.

11 Feb 2009

ViroPharma reports results of trial for Maribavir in bone marrow transplant patients

ViroPharma Incorporated has announced that its Phase 3 trial evaluating maribavir used as prophylaxis in allogeneic stem cell, or bone marrow, transplant (SCT) patients did not achieve its primary endpoint.

10 Feb 2009

Fluid buildup in lungs is part of the damage done by the flu

In a fight against respiratory infections, the body typically produces a little fluid to help the lungs generate a productive cough.

10 Feb 2009

Rituximab maintenance therapy improves survival in patients with relapsed follicular lymphoma

atients with relapsed or refractory follicular lymphoma who continue on maintenance rituximab therapy after chemotherapy have better overall survival than patients who do not receive this treatment, according to a meta-analysis of randomized trials in the February 10 online issue of the Journal of the National Cancer Institute.

10 Feb 2009

New guidelines for prescribing opioid pain drugs

A prestigious panel of pain-management experts representing the American Pain Society (APS) www.ampainsoc.org and the American Academy of Pain Medicine (AAPM) has published the first comprehensive clinical practice guideline to assist clinicians in prescribing potent opioid pain medications for patients with chronic non-cancer pain.

10 Feb 2009

Improving brain processing speed helps memory

Mayo Clinic researchers found that healthy, older adults who participated in a computer-based training program to improve the speed and accuracy of brain processing showed twice the improvement in certain aspects of memory, compared to a control group.

10 Feb 2009

New heart valve inserted through small chest incision

When 91-year-old Irvin Lafferty was diagnosed with severe blockage of his heart valve-hardening that is formally known as aortic valve stenosis-open-heart surgery was out of the question.

10 Feb 2009

Nightly dose of vitamin B12 an effective canker sore therapy

A team of physicians at Ben-Gurion University of the Negev has discovered that a nightly dose of vitamin B12 is a simple, effective and low risk therapy to prevent Recurrent Aphthous Stomatitis (RAS), better known as "canker sores."

10 Feb 2009

When it comes to treating heart attacks, experience matters

New research shows that patients have a much better chance of survival when both their hospital and their physician have a strong track record in treating heart attack with angioplasty and stenting.

9 Feb 2009

Stroke therapy window might be extended past nine hours for some

Some patients who suffer a stroke as a result of a blockage in an artery in the brain may benefit from a clot-busting drug nine or more hours after the onset of symptoms.

9 Feb 2009

Continuation of statin treatment associated with lower risk of death

Patients with high cholesterol levels who continually take statins appear to have a lower risk of death over four to five years, regardless of whether they already have diagnosed heart disease, according to a report in the February 9 issue of Archives of Internal Medicine , one of the JAMA/Archives journals.

9 Feb 2009

Oncostatin M may be a promising drug for treating viral hepatitis and liver cancer

This research, coordinated by the doctors Jesús Prieto, Esther Larrea, Pablo Sarobe, Iranzu González and Rafael Aldabe, has been published in the Journal of Virology ; a journal of the American Society of Microbiology.

9 Feb 2009

Micro RNA plays a key role in melanoma metastasis

Scientists have long wondered how melanoma cells travel from primary tumors on the surface of the skin to the brain, liver and lungs, where they become more aggressive, resistant to therapy, and deadly.

9 Feb 2009

New genomic test can personalize breast cancer treatment

A set of 50 genes can be used to reliably identify the four known types of breast cancer, according to research conducted at Washington University School of Medicine in St. Louis and collaborating institutions.

9 Feb 2009

Multivitamin use not linked to women's risk of cancer, heart disease or death

Postmenopausal women who take multivitamins appear to have the same risk of most common cancers, cardiovascular disease or dying of any cause as women who do not take multivitamin supplements, according to a report in the February 9 issue of Archives of Internal Medicine.

9 Feb 2009

Immunosuppressant medication cyclosporine may be cost-effective for dry eye syndrome

A topical eye emulsion consisting of cyclosporine (a medication used to reduce transplant rejections or to treat arthritis and psoriasis) may be a cost-effective treatment for dry eye syndrome that does not respond to other therapies, according to a report in the February issue of Archives of Ophthalmology.

9 Feb 2009

New understanding of how leukemia develops

In a collaborative study published Feb. 9, 2009, in the Proceedings of the National Academy of Sciences (PNAS), scientists performed a genome-wide expression analysis comparing highly enriched normal blood stem cells and leukemic stem cells, and identified several new pathways that have a key role in cancer development.

9 Feb 2009

Anti-HIV vaginal gel shows promise

An investigational vaginal gel intended to prevent HIV infection in women has demonstrated encouraging signs of success in a clinical trial conducted in Africa and the United States.

9 Feb 2009