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Autopsy study links prostate cancer to single rogue cell

One cell...one initial set of genetic changes - that's all it takes to begin a series of events that lead to metastatic cancer. Now, Johns Hopkins experts have tracked how the cancer process began in 33 men with prostate cancer who died of the disease. Culling information from autopsies, their study points to a set of genetic defects in a single cell that are different for each person's cancer.

16 Apr 2009

NIH grants will strengthen fight against HIV/AIDS-tuberculosis

The Fogarty International Center of the National Institutes of Health today announced it will award $11.75 million over five years in grants to institutions to strengthen the fight against HIV/AIDS and tuberculosis in Haiti, Uganda and China and establish a new program in Tanzania.

16 Apr 2009

New updated clinical guidelines for HIV-associated opportunistic infections

The first complete update in five years of the U.S. guidelines for preventing and treating HIV-associated opportunistic infections has been released by the National Institutes of Health and the Centers for Disease Control and Prevention in cooperation with the HIV Medicine Association of the Infectious Diseases Society of America (IDSA).

16 Apr 2009

Scientists use eye tracking to detect mild dementia in humans

Researchers at the Yerkes National Primate Research Center, Emory University, developed a test in nonhuman primates that is now using infrared eye tracking to detect mild cognitive impairment (MCI) in humans.

15 Apr 2009

Treating sleep disorders in people with traumatic brain injury may not eliminate symptoms

A study in the April 15 issue of the Journal of Clinical Sleep Medicine is the first to assess the effectiveness of treating sleep disorders in adults with a traumatic brain injury (TBI).

15 Apr 2009

Sleeping leads to increased ratings of pain in cancer patients

A study in the April 15 issue of the Journal of Clinical Sleep Medicine suggests that sleep problems lead to increased pain and fatigue in cancer patients.

15 Apr 2009

Cognitive behavioral therapy helps alleviate nonepileptic seizures

Researchers at Rhode Island Hospital have found that cognitive behavioral therapy (CBT) can reduce the frequency of seizures in patients with psychogenic nonepileptic seizures (PNES), along with improving their overall quality of life.

15 Apr 2009

Federal funding for partnership to combat infectious diseases

Oregon Health & Science University and the University of Washington, along with a number of partner institutions across the Northwest, have received federal funding to form a regional research center aimed at combating emerging or re-emerging infectious diseases that pose a serious threat to human health.

15 Apr 2009

Non-drug treatment of Alzheimer's disease: Long-term benefit not proven

Whether people with Alzheimer's disease benefit in the long term from non-drug treatment interventions remains an unanswered question.

15 Apr 2009

Large congenital and solitary intrahepatic arterioportal

A case report to be published on April 7, 2009 in the World Journal of Gastroenterology reported incidental findings of a large and solitary congenital APF in a 73-year-old woman.

15 Apr 2009

Discovery of a new target for novel HIV treatment strategy

The AIDS-causing HIV specifically counteracts the mechanisms of human cells that protect these against viral infections - a special viral protein marks protective cellular proteins for their rapid destruction and thus diminishes the cell's supply.

15 Apr 2009

Gene therapy for muscular dystrophy a step closer

Researchers have cleared a safety hurdle in efforts to develop a gene therapy for a form of muscular dystrophy that disables patients by gradually weakening muscles near the hips and shoulders.

15 Apr 2009

OncoGel: New system for delivering chemotherapy for patients with esophageal cancer

Gastroenterologists at Rush University Medical Center are studying the safety and efficacy of a new system for delivering chemotherapy for patients with esophageal cancer, a rare, but deadly disease that attacks the throat.

15 Apr 2009

Topical bevacizumab therapy effective in treating corneal blood vessels growth that can cause blindness

Researchers at the Massachusetts Eye and Ear Infirmary and Schepens Eye Research Institute have concluded that short-term topical bevacizumab therapy reduces the severity of corneal neovascularization (formation of new blood vessels in the cornea that can create impaired vision or vision loss) without local or systemic adverse effects.

15 Apr 2009

Mycophenolate mofetil may be an alternative therapy for lupus nephritis

Lupus is a rare but serious disease that mainly affects women of child-bearing age and occurs when the body's immune system goes awry, damaging a variety of organs.

15 Apr 2009

Type 1 diabetes controlled by stem cell transplants therapy

Scientists in the United States have found that stem cell transplants enabled people with type 1 diabetes to manage for as long as four years without needing insulin injections and to maintain good glycemic control - such patients typically need daily insulin therapy to control their diabetes.

15 Apr 2009