Fatigue News and Research

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Nonmotor symptoms may underlie Parkinson’s sleep complaints

In people with Parkinson’s disease, symptoms and comorbidities associated with insomnia differ from those associated with daytime sleepiness, US researchers report.

25 Nov 2013

CHMP adopts positive opinion for ABRAXANE with gemcitabine for treatment of metastatic pancreas

Celgene International Sàrl, a wholly-owned subsidiary of Celgene Corporation, today announced that the European Medicines Agency's: Committee for Medicinal Products for Human Use has adopted a positive opinion for ABRAXANE (paclitaxel formulated as albumin bound nanoparticles, or nab-paclitaxel) in combination with gemcitabine for first-line treatment of adult patients with metastatic adenocarcinoma of the pancreas.

25 Nov 2013

Patients with symptom clusters after surgery for esophageal cancer have increased mortality risk

A new study has found that several months after surgery for esophageal cancer, different symptoms cluster together in different types of patients. In addition, patients with certain symptom clusters have an increased risk of dying from their disease.

25 Nov 2013

NEXAVAR tablets receive FDA approval for treatment of patients with thyroid cancer

Bayer HealthCare and Onyx Pharmaceuticals, Inc., an Amgen subsidiary, today announced that the U.S. Food and Drug Administration has approved a supplemental New Drug Application for the oral multi-kinase inhibitor NEXAVAR (sorafenib) tablets for the treatment of patients with locally recurrent or metastatic, progressive, differentiated thyroid carcinoma refractory to radioactive iodine treatment.

23 Nov 2013

U-M study explores exercise-induced iron-deficiency anemia in female runners

When Kaitlyn Patterson's fatigue progressed to hyperventilating even during slow runs, and then forced her to quit high school distance running for the season, she knew something was very wrong. Patterson had exercise-induced iron-deficiency anemia, a common, perplexing problem among elite female athletes, especially endurance runners. Later, as a University of Michigan sophomore, she was so interested in the topic that she applied for an undergraduate research position in the lab of Peter Bodary, U-M clinical assistant professor of movement science and health & fitness.

22 Nov 2013

Tasquinimod drug effective for men with metastatic castration-resistant prostate cancer

An investigational prostate cancer treatment slows the disease's progression and may increase survival, especially among men whose cancer has spread to the bones, according an analysis led by the Duke Cancer Institute.

20 Nov 2013

NSU researchers selected to participate in DoD Gulf War Illness Research Program Consortium

Nova Southeastern University President and CEO George L. Hanbury II, Ph.D., recently announced that a NSU research team led by Mariana Morris, Ph.D., and Nancy Klimas, M.D., was selected by the U.S. Department of Defense as one of two DoD Gulf War Illness Research Program Consortium awardees.

20 Nov 2013

New hope for patients whose melanoma has metastasised to the brain

New data show that in patients whose melanoma (BRAF V600 mutation-positive) has spread (metastasised) to the brain, Zelboraf (vemurafenib) extends life expectancy by over six months compared to chemotherapy.1 These results are welcome news for patients suffering from metastatic melanoma, as up to half of these patients are diagnosed with brain metastases with many given less than six months to live.1

18 Nov 2013

Imbruvica gets FDA approval for treatment of mantle cell lymphoma

The U.S. Food and Drug Administration today approved Imbruvica (ibrutinib) to treat patients with mantle cell lymphoma, a rare and aggressive type of blood cancer.

13 Nov 2013

Lifestyle changes boost QoL during long-term ADT

A study shows that a lifestyle intervention, involving an exercise program and dietary advice, improves disease-specific quality of life in sedentary men with advanced prostate cancer who are receiving long-term androgen-deprivation therapy.

11 Nov 2013

Research findings may lead to new treatments, approaches for controlling multiple sclerosis

Scientists are gaining a new level of understanding of multiple sclerosis that may lead to new treatments and approaches to controlling the chronic disease, according to new research released today at Neuroscience 2013, the annual meeting of the Society for Neuroscience and the world's largest source of emerging news about brain science and health.

10 Nov 2013

Aptiom receives FDA approval to treat seizures associated with epilepsy

The U.S. Food and Drug Administration today approved Aptiom (eslicarbazepine acetate) as an add-on medication to treat seizures associated with epilepsy.

10 Nov 2013

Viewpoints: The battle over one woman's medical story; why Mass. didn't see a wave of cancellations; politicians' love of anecdotes

Edie Littlefield Sundby may not have thought she'd ignite a national debate when the stage-4 cancer survivor asked us to publish her Monday op-ed on losing her oncologist due to the Affordable Care Act. But she certainly has, and it's important to understand why. Mrs. Sundby and millions like her must be denied their medical choices if ObamaCare is going to work as its liberal planners intend (11/6).

8 Nov 2013

Landmark clinical trial of artificial aortic heart valve shows positive results

Loyola University Medical Center is the only Chicago hospital participating in a landmark clinical trial of an artificial aortic heart valve that does not require open heart surgery.

From Medtronic 8 Nov 2013

Vitamin C can improve skeletal muscle fatigue in COPD patients

Chronic obstructive pulmonary disease—a health problem in which the lungs lose their inherent springiness, making it progressively harder to breathe—can have a dramatic effect on the ability to exercise and even perform simple activities of daily life because of the disease's fallout effects on skeletal muscles.

8 Nov 2013

HSS study shows exercise program helps reduce arthritis pain for Asian seniors

Experts say it's never too late to reap the benefits of exercise, and a program offered in New York City senior centers is improving quality of life for many older adults.

5 Nov 2013

Pivotal Phase III STARTVerso data shows efficacy of faldaprevir in genotype-1 infected HCV patients

Boehringer Ingelheim today announced new data from its Phase III clinical trial programme, STARTVerso, which evaluates faldaprevir in combination with pegylated interferon and ribavirin (PegIFN/RBV).

5 Nov 2013

Disruption of brain signals contributes to increased pain sensitivity in fibromyalgia patients

New research indicates that a disruption of brain signals for reward and punishment contributes to increased pain sensitivity, known as hyperalgesia, in fibromyalgia patients. Results published in Arthritis & Rheumatism, a journal of the American College of Rheumatology, suggest that this altered brain processing might contribute to widespread pain and lack of response to opioid therapy in patients with fibromyalgia.

5 Nov 2013

CHEO-led study confirms validity, reliability of quality of life measurement tool for thalassemia major

A CHEO-led multi-site North American study, headed by Dr. Robert Klaassen, lead investigator at CHEO and associate professor in the University of Ottawa's Department of Pediatrics, has confirmed the validity and reliability of a quality of life measurement tool for children and adults with thalassemia major.

5 Nov 2013

Biomedical testing: an interview with Ed Moriarty, General Manager of the ElectroForce Systems Group of Bose Corporation

An interview with Ed Moriarty, discussing how Bose are involved in the development of advanced testing equipment for medical devices.

From TA Instruments 4 Nov 2013

Fatigue News and Research

Nonmotor symptoms may underlie Parkinson’s sleep complaints

CHMP adopts positive opinion for ABRAXANE with gemcitabine for treatment of metastatic pancreas

Patients with symptom clusters after surgery for esophageal cancer have increased mortality risk

NEXAVAR tablets receive FDA approval for treatment of patients with thyroid cancer

U-M study explores exercise-induced iron-deficiency anemia in female runners

Tasquinimod drug effective for men with metastatic castration-resistant prostate cancer

NSU researchers selected to participate in DoD Gulf War Illness Research Program Consortium

New hope for patients whose melanoma has metastasised to the brain

Imbruvica gets FDA approval for treatment of mantle cell lymphoma

Lifestyle changes boost QoL during long-term ADT

Research findings may lead to new treatments, approaches for controlling multiple sclerosis

Aptiom receives FDA approval to treat seizures associated with epilepsy

Viewpoints: The battle over one woman's medical story; why Mass. didn't see a wave of cancellations; politicians' love of anecdotes

Landmark clinical trial of artificial aortic heart valve shows positive results

Vitamin C can improve skeletal muscle fatigue in COPD patients

HSS study shows exercise program helps reduce arthritis pain for Asian seniors

Pivotal Phase III STARTVerso data shows efficacy of faldaprevir in genotype-1 infected HCV patients

Disruption of brain signals contributes to increased pain sensitivity in fibromyalgia patients

CHEO-led study confirms validity, reliability of quality of life measurement tool for thalassemia major

Biomedical testing: an interview with Ed Moriarty, General Manager of the ElectroForce Systems Group of Bose Corporation

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