Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Researchers identify antioxidant mechanisms involved in protection against heart disease

Zvonimir Katusic, M.D., Ph.D., and Mayo colleagues have identified antioxidant mechanisms essential for regenerative function of endothelial progenitor cells (EPCs).

30 Apr 2007

Small amounts of stem/progenitor cells from bone marrow enhance repair of damaged tissues

New studies in the laboratory of Dr. Darwin J. Prockop, Director of Tulane University's Center for Gene Therapy, are shedding light on the previously mysterious mechanism through which even relatively small amounts of stem/progenitor cells taken from a patient's own bone marrow enhance repair of damaged tissues.

30 Apr 2007

New gene discovered in human stem cells may benefit transplant patients

Oxford scientists have revealed a link between a gene and the activity of human blood stem cells, giving hope that stem cell transplant success for blood cancer patients may be significantly improved.

27 Apr 2007

Naturally occurring compound found in many fruits and vegetables as well as red wine, selectively kills leukemia cells

These findings, which were published online March 20 in the Journal of Biological Chemistry and will be in press on May 4, offer hope for a more selective, less toxic therapy for leukemia.

24 Apr 2007

Translocation kidney cancer after chemotherapy in childhood

This article out of Johns Hopkins reviewed the risk of renal cell carcinoma occurring as a secondary malignancy after chemotherapy in childhood.

21 Apr 2007

Chinese herbs may help women with breast cancer

Using Chinese herbs either alone or in conjunction with chemotherapy may help protect a breast cancer patient’s bone marrow and immune system, as well as improving the woman’s overall quality of life.

19 Apr 2007

New discoveries about stem cells in leukemia, breast and colon cancer

Recent discoveries about the role of stem cells in cancer have altered the landscape of cancer research. With each new study, scientists are learning more about cancer-initiating properties of stem cells at organ sites and throughout the body.

19 Apr 2007

Scientists tackle cancer with different approaches

Studies presented at the 2007 meeting of the American Association for Cancer Research show how researchers are using the new, as well as the natural, to help design and test new drugs to treat cancer.

18 Apr 2007

Anti-anemia drug darbepoetin alfa no better than placebo for cancer patients

Results from a phase III drug trial indicate that an anti-anemia drug did not significantly decrease the need for blood transfusions in patients not on chemotherapy, and decreased overall patient survival when compared to placebo, according to researchers from the UCLA Medical Center at the 2007 Annual Meeting of the American Association for Cancer Research.

17 Apr 2007

New player in the development T-cell acute lymphoblastic leukemia

Leuven, Belgium -- Leukemia, or cancer of the bone marrow, strikes some 700 Belgians each year.

16 Apr 2007

Chaetocin shows promise as a new anti-myeloma agent

Mayo Clinic Cancer Center researchers have found that chaetocin, a by-product of a common wood mold, has promise as a new anti-myeloma agent. Results of their study, being presented today at the American Association for Cancer Research annual meeting, show the by-product to be more effective than currently used therapies at killing multiple myeloma cells.

16 Apr 2007

Leukemic cells find safe haven in bone marrow

The cancer drug asparaginase fails to help cure some children with acute lymphoblastic leukemia (ALL) because molecules released by certain cells in the bone marrow counteract the effect of that drug, according to St. Jude investigators.

16 Apr 2007

Stranger than science fiction?...Human sperm created from bone marrow

A team of scientists have created primitive human sperm in the laboratory by using bone-marrow tissue from male volunteers.

16 Apr 2007

GlaxoSmithKline initiates study of PROMACTA in chronic idiopathic thrombocytopenic purpura

GlaxoSmithKline has announced the initiation of a global, open-label, single group trial that will assess the efficacy, safety and tolerability of PROMACTA (eltrombopag olamine) in patients previously treated for chronic idiopathic thrombocytopenic purpura (ITP).

15 Apr 2007

Human bone marrow has been used to create early-stage sperm cells

For the experiment, Prof Nayernia and his team took bone marrow from male volunteers and isolated the mesenchymal stem cells. These cells have previously been found to grow into other body tissues such as muscle.

15 Apr 2007

Dysfunctional DNA repair pathways

Individuals who inherit two mutant copies of any one of about 12 genes that make the proteins of the Fanconi Anemia (FA) pathway develop FA, which is characterized by increased incidence of cancer and bone marrow failure, among other things.

15 Apr 2007

Rep. Dave Weldon comments on stem therapy and type I diabetes

In yet another advance in adult stem cell therapy, the Journal of the American Medical Association (JAMA) today released a study in which 14 of 15 Juvenile Diabetes patients demonstrated significant improvement as a result of an adult stem cell treatment.

11 Apr 2007

Stem cells re-set the immune systems of diabetes patients

Researchers in Brazil and the U.S. have conducted an experiment which shows that stem cells can "re-set" the immune systems of diabetes patients.

10 Apr 2007

Modified bone marrow cells help recovery in an animal model of multiple sclerosis

These findings will need to be repeated in further animal models before the implications for human disease are clear; however, they open up an avenue of further research.

10 Apr 2007

Lower doses of dexamethasone for multiple myeloma recommended

The International Myeloma Foundation (IMF) - supporting research and providing education, advocacy and support for myeloma patients, families, researchers and physicians - today said physicians should consider lowering the dose of the steroid dexamethasone when treating patients with multiple myeloma.

5 Apr 2007