Fever News and Research

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UTMB researchers improve existing experimental vaccine for Rift Valley fever virus

University of Texas Medical Branch researchers have significantly improved an existing experimental vaccine for Rift Valley fever virus, making possible the development of a more effective defense against the dangerous mosquito-borne pathogen.

28 Jun 2012

Pediatric Hodgkin lymphoma can be treated without radiation and intensive chemotherapy

A multicenter trial showed that nearly half of young patients with early-stage Hodgkin lymphoma can be cured without undergoing either irradiation or intensive chemotherapy that would leave them at risk for second cancers, infertility, heart and other problems later.

28 Jun 2012

FDA approves test for dengue virus infection

The first test that can detect the presence of the dengue virus itself rather than antibodies to the virus has been approved for use by the US Food and Drug Administration.

27 Jun 2012

Genentech's Perjeta helps people with HER2-positive metastatic breast cancer live longer

Genentech, a member of the Roche Group, announced today that people with HER2-positive metastatic breast cancer (mBC) lived significantly longer (overall survival) when treated with the combination of Perjeta (pertuzumab), Herceptin (trastuzumab) and docetaxel chemotherapy, compared to Herceptin and docetaxel chemotherapy alone in the Phase III CLEOPATRA study.

23 Jun 2012

FDA approves CDC DENV-1-4 Real Time RT PCR Assay to treat dengue

The Centers for Disease Control and Prevention has developed a new diagnostic test to detect the presence of dengue virus in people with symptoms of dengue fever or dengue hemorrhagic fever. The test, called the CDC DENV-1-4 Real Time RT PCR Assay, has been authorized by the Food and Drug Administration for use in the United States and can be performed using equipment and supplies many public health laboratories already use to diagnose influenza.

21 Jun 2012

Roseola virus behind one-third of febrile seizures in young children

Researchers have discovered that infection with two of the roseola viruses, which are responsible for a common childhood rash, appear to increase a child’s risk for prolonged seizures and fever and may increase future temporal lobe epilepsy risk.

20 Jun 2012

New clinical data for ZEVALIN Injection for intravenous use presented at 17th EHA Congress

Spectrum Pharmaceuticals, Inc., a biotechnology company with fully integrated commercial and drug development operations with a primary focus in oncology and hematology, today announced new clinical data presented in an oral presentation for ZEVALIN (ibritumomab tiuxetan) Injection for intravenous use at the 17th Congress of the European Hematology Association (EHA).

19 Jun 2012

Tips to avoid becoming a mosquito meal

Summer has barely begun but it's likely many people have already encountered one of the season's most ubiquitous pests - the mosquito. As is the case with many other insects, mosquitoes have made an early emergence after a mild winter and rainy spring. The National Pest Management Association (NPMA) warns that this might be one of the worst seasons yet, so break out the repellant.

18 Jun 2012

Wellcome Trust awards University of Maryland $4M to accelerate development of conjugate NTS vaccine

The University of Maryland School of Medicine's Center for Vaccine Development (CVD) has received a $4 million Strategic Translation Award from the prestigious Wellcome Trust to support a collaboration with Bharat Biotech for clinical development of a new conjugate vaccine to prevent the potentially lethal infectious disease caused by invasive non-typhoidal Salmonella.

18 Jun 2012

Latest allergy research presented at EAACI Congress 2012

Ground-breaking research results about stress during pregnancy and changes in pollen potency across Europe will be presented - among other novel research - at the world's leading congress on allergy and immunology - the EAACI Congress 2012 - that will open tomorrow in Geneva, Switzerland.

16 Jun 2012

Study strengthens link between HHV-6B and mesial temporal lobe epilepsy

A ten-year NIH-funded study has determined that a third of infants with prolonged seizures and fever suffer from either a new or reactivated roseola virus infection. Roseola viruses are the cause of the common childhood rash, but can also cause limbic encephalitis, a condition that frequently progresses to epilepsy. Investigators discovered one of the roseola viruses, human herpesvirus-6B (HHV-6B) in the blood of 32% of 169 infants with prolonged seizures, a condition known as status epilepticus.

15 Jun 2012

FDA approves GSK’s MenHibrix to treat meningococcal and Hib diseases

GlaxoSmithKline plc announced today that the U.S. Food and Drug Administration (FDA) has approved the vaccine MenHibrix [Meningococcal Groups C and Y and Haemophilus b Tetanus Toxoid Conjugate Vaccine].

15 Jun 2012

FDA approves Menhibrix for vaccination against meningococcal and Hib diseases

The U.S. Food and Drug Administration today approved Menhibrix, a combination vaccine for infants and children ages 6 weeks through 18 months, for prevention of invasive disease caused by Neisseria meningitidis serogroups C and Yand Haemophilus influenzae type b.

15 Jun 2012

Hay fever vaccine shows efficacy in phase IIa trial

A novel vaccine for grass pollen allergy has shown significant improvements for patients in a Phase IIa trial. The vaccine BM32 is based on an innovative recombinant peptide carrier technology that allows for fewer injections and shows fewer side effects compared with other immunotherapy treatments for allergy sufferers. BM32 has been developed by Biomay AG, an Austrian biopharmaceutical company specialized in the discovery and development of innovative allergy therapeutics. The company has already initiated a Phase IIb trial for BM32 with 180 allergic patients.

14 Jun 2012

Roseola virus accounts for one third of febrile status epilepticus cases

New research shows that human herpesviruses (HHV)-6B and HHV-7, commonly know as roseola virus), account for one third of febrile status epilepticus (FSE) cases. Results of the FEBSTAT prospective study now available in Epilepsia, a journal published by Wiley-Blackwell on behalf of the International League Against Epilepsy (ILAE), suggest that HHV-6B may be involved in the development of epilepsy and further research is urgently needed.

14 Jun 2012

Transgenic mosquitoes can control malaria

Mosquitoes bred to be unable to infect people with the malaria parasite are an attractive approach to helping curb one of the world's most pressing public health issues, according to UC Irvine scientists.

13 Jun 2012

Consequences of female genital mutilation could be reduced by reconstructive surgery

Reconstructive surgery after female genital mutilation (FGM) appears to reduce pain and restore sexual pleasure in women, according to the first large prospective trial to assess long-term outcomes of a new surgical technique published Online First in The Lancet. Over the past 10 years, between 130 and 140 million women worldwide have been subject to FGM.

12 Jun 2012

Promising results for dabrafenib in advanced melanoma

The BRAF inhibitor dabrafenib shows promising results for treatment of advanced melanoma, both alone and in combination with the MEK inhibitor trametinib, show results from two studies presented at the American Society of Clinical Oncology Annual Meeting in Chicago, Illinois, USA.

8 Jun 2012

Magazine examines efforts to biologically alter bugs to fight human diseases

Pacific Standard magazine examines efforts by researchers around the globe to biologically modify bugs to fight human diseases, such as dengue fever. "Biologically altering bugs isn't entirely new; it's been done for nearly half a century to protect crops. ...

8 Jun 2012

Anti-TNFs increase risk of shingles in patients with inflammatory rheumatic diseases

Patients with inflammatory rheumatic diseases (IRD) treated with anti-tumour necrosis factor medications (anti-TNFs) have a 75% greater risk of developing herpes zoster, or shingles, than patients treated with traditional disease modifying anti-rheumatic drugs (DMARDs), according to a meta-analysis presented today at EULAR 2012, the Annual Congress of the European League Against Rheumatism.

8 Jun 2012

Fever News and Research

UTMB researchers improve existing experimental vaccine for Rift Valley fever virus

Pediatric Hodgkin lymphoma can be treated without radiation and intensive chemotherapy

FDA approves test for dengue virus infection

Genentech's Perjeta helps people with HER2-positive metastatic breast cancer live longer

FDA approves CDC DENV-1-4 Real Time RT PCR Assay to treat dengue

Roseola virus behind one-third of febrile seizures in young children

New clinical data for ZEVALIN Injection for intravenous use presented at 17th EHA Congress

Tips to avoid becoming a mosquito meal

Wellcome Trust awards University of Maryland $4M to accelerate development of conjugate NTS vaccine

Latest allergy research presented at EAACI Congress 2012

Study strengthens link between HHV-6B and mesial temporal lobe epilepsy

FDA approves GSK’s MenHibrix to treat meningococcal and Hib diseases

FDA approves Menhibrix for vaccination against meningococcal and Hib diseases

Hay fever vaccine shows efficacy in phase IIa trial

Roseola virus accounts for one third of febrile status epilepticus cases

Transgenic mosquitoes can control malaria

Consequences of female genital mutilation could be reduced by reconstructive surgery

Promising results for dabrafenib in advanced melanoma

Magazine examines efforts to biologically alter bugs to fight human diseases

Anti-TNFs increase risk of shingles in patients with inflammatory rheumatic diseases

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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