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Brain organoids provide new insights into HSV-1 encephalitis

The herpes simplex virus-1 can sometimes cause a dangerous brain infection. Combining an anti-inflammatory and an antiviral could help in these cases, report scientists with the Rajewsky and Landthaler labs and the Organoid Platform at the Max Delbrück Center in Nature Microbiology.

22 Jun 2023

Understanding the molecular mechanisms responsible for antimony drug resistance in Leishmania parasites

Leishmaniasis is a tropical disease caused by parasites known as Leishmania, which are transmitted to humans and animals through the bites of more than 90 species of sand flies.

22 Jun 2023

Study reveals why some women with deadly ovarian cancer respond better to treatment than others

New research is increasing our understanding about why some women with the most lethal form of ovarian cancer respond much better to treatment than others.

21 Jun 2023

Novel approach to multimodal aging clock for interpretable age prediction and target discovery

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 11, entitled, "Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature importance analysis for aging and age-related disease target discovery."

21 Jun 2023

Uncovering the hidden genetic connections behind COVID-19 and comorbidities

Researchers performed a protein diffusion network analysis using tissue-specific GRNs to identify predispositions to COVID-19.

21 Jun 2023

The Fight Against Antimicrobial Resistance: A Promising Broad Host-Range CRISPR-Cas9 Delivery Tool for AMR Plasmid Removal

Study removes AMR plasmids using a mobile, broad-host-range CRISPR-Cas9 delivery tool.

21 Jun 2023

Newborn screening facilitates early identification of infants with severe combined immunodeficiency

Introducing widespread screening of newborns for a deadly disease called severe combined immunodeficiency, or SCID, followed by early treatment boosted the five-year survival rate of children with the disorder from 73% before the advent of screening to 87% since, researchers report.

20 Jun 2023

New embryonic cell type that self-destructs to protect the developing fetus discovered

Scientists studying gene activity data of the early human embryo have discovered an overlooked type of cell which self-destructs within days of forming, as part of a quality control process to protect the developing fetus.

20 Jun 2023

Targeting Phage Therapy 2023 showcased the progress and possibilities of phage therapy in future

The 6th World Congress on Targeting Phage Therapy 2023 that was held on June 1-2 in Paris, and gathered more than 150 attendees from 30+ different countries. Targeting Phage Therapy 2023 included more than 71 presentations between major talks, short orals, and posters.

20 Jun 2023

Researchers use an unprecedented stem cell zoo to study developmental time

In humans, pregnancy lasts around nine months. In mice, only 20 days, and in rhinoceroses, as long as 17 months. Although many mammalian species go through the same stages during embryo development, the speed of development differs substantially across animals.

20 Jun 2023

The contribution of transcription factor ROB1 to the pathophysiology of C. albicans-induced candidal infections

Researchers evaluated the function of the zinc finger transcription factor ROB1 and its two phenotypically distinct alleles in the pathogenesis of Candida albicans infections.

20 Jun 2023

Urban jungle: How city living may impact mental health

Researchers explore the effects of the urban environment on adult mental health.

19 Jun 2023

Scientists develop new technique to peer into the genome's spatial architecture

People who owned black-and-white television sets until the 1980s didn't know what they were missing until they got a color TV.

19 Jun 2023

New data demonstrates severe AMR among non-typhoidal Salmonella isolated from food in China

Announcing a new article publication for Zoonoses journal. Non-typhoidal Salmonella (NTS) is a major cause of human salmonellosis globally. Food animals are major NTS reservoirs.

19 Jun 2023

Is vaginal microbiota transfer intervention for infants delivered by C-section beneficial to their neurodevelopment?

Researchers examined the impact of vaginal microbiota transfer on the neurodevelopment of infants born via cesarean section.

19 Jun 2023

Study provides a promising strategy for the treatment of neuroblastoma

Announcing a new publication for Acta Materia Medica journal. Neuroblastoma (NB) is a common solid tumor in children and infants, the formation and regression of which is closely linked to the tumor-host immune relationship.

19 Jun 2023

Broader search needed for successful management of eosinophilic gastritis

The good news: a monoclonal antibody treatment called benralizumab proved quite effective in a clinical trial at depleting the number of eosinophils found in the blood and digestive tract tissues of patients with eosinophilic gastritis.

16 Jun 2023

Genetic mechanisms that underlie healthy high-elevation pregnancies may have deep evolutionary roots

Pregnancy at high elevations often is associated with low birth weights and other complications. These challenges occur in a wide range of mammals, from deer mice to human beings.

16 Jun 2023

Researchers identify several steps in a cellular process responsible for triggering inflammatory responses

Cedars-Sinai investigators have identified several steps in a cellular process responsible for triggering one of the body's important inflammatory responses.

16 Jun 2023

MGI partners with Xpress Genomics to advance deep single-cell RNA-sequencing technologies

MGI, a company committed to building core tools and technology to lead life science, announced the signing of a licensing agreement with Xpress Genomics, a leading Stockholm-based company specializing in automated and scalable RNA-sequencing strategies.

From MGI 16 Jun 2023

Genes News and Research

Brain organoids provide new insights into HSV-1 encephalitis

Understanding the molecular mechanisms responsible for antimony drug resistance in Leishmania parasites

Study reveals why some women with deadly ovarian cancer respond better to treatment than others

Novel approach to multimodal aging clock for interpretable age prediction and target discovery

Uncovering the hidden genetic connections behind COVID-19 and comorbidities

The Fight Against Antimicrobial Resistance: A Promising Broad Host-Range CRISPR-Cas9 Delivery Tool for AMR Plasmid Removal

Newborn screening facilitates early identification of infants with severe combined immunodeficiency

New embryonic cell type that self-destructs to protect the developing fetus discovered

Targeting Phage Therapy 2023 showcased the progress and possibilities of phage therapy in future

Researchers use an unprecedented stem cell zoo to study developmental time

The contribution of transcription factor ROB1 to the pathophysiology of C. albicans-induced candidal infections

Urban jungle: How city living may impact mental health

Scientists develop new technique to peer into the genome's spatial architecture

New data demonstrates severe AMR among non-typhoidal Salmonella isolated from food in China

Is vaginal microbiota transfer intervention for infants delivered by C-section beneficial to their neurodevelopment?

Study provides a promising strategy for the treatment of neuroblastoma

Broader search needed for successful management of eosinophilic gastritis

Genetic mechanisms that underlie healthy high-elevation pregnancies may have deep evolutionary roots

Researchers identify several steps in a cellular process responsible for triggering inflammatory responses

MGI partners with Xpress Genomics to advance deep single-cell RNA-sequencing technologies

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