Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Purdue biologists visualize protein interaction that may initiate viral infection

Biologists at Purdue University have taken a "snapshot" of a Velcro-like protein on a cell's surface just after it attached to the dengue virus, a linkup thought to initiate the early stages of infection.

16 Feb 2006

Mystery of cot death may be explained

A failure to 'gasp' has long been proposed as the basis for sudden infant death syndrome, or cot death. A team at the University of Bristol has discovered a subset of cells in the brain that have the ability to self-generate nervous impulses, which appear essential for gasping. These cells have been termed 'pacemakers'.

16 Feb 2006

Predicting risk of coronary artery disease

The extent of anatomic coronary artery disease, along with age and the presence of diabetes, is a strong predictor of subsequent death due to any cause and due to coronary artery disease (CAD).

16 Feb 2006

Brain scans may detect neurological decline in normal people

Brain scans may detect neurological changes in people who exhibit no outward signs of cognitive decline but who later develop dementia or mental impairment, according to the results of a new study led by researchers at the University of California, Berkeley.

16 Feb 2006

Research may help explain Alzheimer's memory loss

Based on laboratory research, scientists at Georgetown University Medical Center have a new theory as to why people with Alzheimer's disease have trouble performing even the simplest memory tasks, such as remembering a family member's name.

16 Feb 2006

Less is more hypothesis - gene loss may explain unique human traits

Humans and chimps share most of their genes, yet they differ dramatically in many ways - their walk, the sizes of their brains and their capacities for speech and language, for example.

16 Feb 2006

Scientists discover how to make human collagen in the lab

It is the most important structural protein in the body, reinforcing connective tissue, bones and teeth, and forming long, fibrous cables to strengthen tendons. Collagen forms sheets of tissue that support the skin and every internal organ.

16 Feb 2006

New insight into pathogenic mechanisms underlying basal-like breast cancers

Basal-like breast cancers (BLC) are highly aggressive tumors with a relatively poor prognosis that account for approximately 15% of sporadic human breast cancer.

16 Feb 2006

Study identifies compounds that overcome a specific type of resistance to chemotherapeutic-induced apoptosis

Treatment of human cancer is often impeded when cancer cells develop resistance to drugs that are designed to induce a type of programmed cell death called apoptosis.

16 Feb 2006

Taking aim at one of mankind's most common diseases

A detailed structural picture of a molecule that plays a key role in activating the Epstein Barr Virus in human cells has now been obtained by researchers at the European Molecular Biology Laboratory (EMBL) and the Institute of Molecular and Structural Virology (IVMS), associated with the University Joseph Fourier and the CNRS, in Grenoble.

16 Feb 2006

Researchers capture the electrical activity of a single sperm cell

Researchers at Children's Hospital Boston and the Howard Hughes Medical Institute have, for the first time, captured the electrical activity of a single sperm cell. The technically difficult maneuver, reported in Nature, allows the first measurement of the currents that flow across the sperm's outer membrane.

14 Feb 2006

Researchers capture the electrical activity of a single sperm cell

14 Feb 2006

Measuring levels of NT-proBNP protein predicts long-term risk in patients with shortness of breath

Researchers from Massachusetts General Hospital (MGH) have shown that a blood test previously found useful for diagnosing heart failure and determining prognosis in several cardiovascular conditions can also predict the risk of death among patients coming to hospital emergency departments with shortness of breath.

14 Feb 2006

New understanding of the molecular genetics of successful fertilization

A new paper in the February 15th issue of Genes & Development lends novel insight into the cellular changes that occur in sperm while they reside in the female reproductive tract - providing a new understanding of the molecular genetics of successful fertilization.

14 Feb 2006

Low-carb diets effective, but may raise cholesterol levels

A synthesis of data from five previous clinical trials suggests that both low-fat and low-carbohydrate diets appear to be effective for weight loss up to one year, but low-carbohydrate diets may be linked to higher overall and LDL or "bad" cholesterol levels, according to a study in the Archives of Internal Medicine.

14 Feb 2006

Broccoli, cauliflower and cabbage help repair damaged DNA

Need another reason to eat your vegetables? New research shows that some of them contain chemicals that appear to enhance DNA repair in cells, which could lead to protection against cancer development, say Georgetown University Medical Center researchers.

14 Feb 2006

Stem cell injections may help those with severe peripheral artery disease

Indiana University School of Medicine scientists have begun a unique clinical trial using stem cell injections as a treatment that could offer hope to tens of thousands of people who face sores, ulcers and even amputations due to severe peripheral artery disease.

14 Feb 2006

FDA affirms safety of Aspartame

The Calorie Control Council has stated that a rat study conducted by Italy's Ramazzini Institute is totally contradictory to the extensive scientific research and regulatory reviews conducted on aspartame. The U.S. Food & Drug Administration (FDA) has said they are not recommending any changes in the use of aspartame.

13 Feb 2006

Statins show beneficial effect on rheumatoid arthritis

Statins, a class of drugs widely used to treat high cholesterol, have also recently been studied for their potential role in inflammation and other cell processes, including immune response.

13 Feb 2006

Cellular discovery suggests possibilities for drug therapy for kidney disease

Scientists at the University of California, Santa Barbara have reported a discovery at the cellular level that suggests possibilities for drug therapy for kidney disease.

13 Feb 2006