Bone Mineral Density News and Research

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$DXA scan should be done at shorter intervals for women at high risk for fracture$

DXA scan should be done at shorter intervals for women at high risk for fracture

Although a recent study suggests that women with normal results on dual-energy X-ray absorptiometry (DXA) scans at ages 67 and older may wait up to 15 years for a second test, a Viewpoint article published today in the Journal of Bone and Mineral Research (JBMR) cautions that such a lengthy interval is inappropriate for many adults.

2 Mar 2012

Mechanical dose of load through muscle force may slow bone loss in SCI patients

Loss of bone density leads to brittle bones that fracture easily. It is a major complication of spinal cord injury (SCI), which affects about 250,000 Americans every year.

17 Feb 2012

Genzyme announces four-year data from eliglustat tartrate phase 2 trial on Gaucher disease type 1

Genzyme, a Sanofi company, announced today four-year follow-up data from patients enrolled in the phase 2 clinical trial for its investigational oral therapy for Gaucher disease type 1 known as eliglustat tartrate.

8 Feb 2012

Exemestane has negative effect on postmenopausal women's bone health

Exemestane, a drug used in the prevention of breast cancer in postmenopausal women, has a negative effect on bone density and structure in these women, despite calcium and vitamin D supplements.

8 Feb 2012

$Heart failure associated with 30% increase in major fractures$

Heart failure associated with 30% increase in major fractures

Heart failure is associated with a 30 percent increase in major fractures and also identifies a high-risk population that may benefit from increased screening and treatment for osteoporosis, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

3 Feb 2012

Research roundup: 'No individual mandate' scenarios; Breaking down health care expenditures

This paper expands 2011 research examining whether the health law's controversial individual mandate – which requires most people to have health insurance -- will be effective.

21 Jan 2012

Testing for osteoporosis – how often?

A new study shows that many women who get screened for osteoporosis may not need it. It suggests that the current guidelines result in too many unnecessary tests, increasing costs and sometimes spurring unnecessary treatment.

19 Jan 2012

Women aged 67 years with normal bone mineral density may not need screening again for 15 years

The U.S. Preventive Services Task Force and other organizations have recommended that women ages 65 and older be routinely screened for osteoporosis using bone mineral density (BMD) screening. However, how often women should be screened is a topic that remains controversial and undecided, with no definitive scientific evidence to provide guidance.

19 Jan 2012

Gilead Sciences receives FDA approval for Viread to treat pediatric HIV infection

Gilead Sciences, Inc. announced today that the U.S. Food and Drug Administration (FDA) has approved Viread in combination with other antiretroviral agents for the treatment of HIV-1 infection in pediatric patients ages 2-12.

19 Jan 2012

FRAX tool now available as version 3.5 in 18 languages

FRAX, which is available free online at http://www.shef.ac.uk/FRAX/, is being used by an increasing number of physicians around the world - the online version alone is used to calculate 10-year probability of fracture in approximately 2.8 million patients annually, with numbers growing steadily.

17 Jan 2012

$Physician notification system can help prevent further fractures in osteoporotic patients$

Physician notification system can help prevent further fractures in osteoporotic patients

A simple physician notification system can help prevent further fractures in osteoporotic patients who have had already had fractures, according to a study in CMAJ.

20 Dec 2011

BioInvent announces new BI-505 preclinical data on multiple myeloma

BioInvent International AB announced today that new preclinical data has been presented on its BI-505 programme that demonstrates anti-cancer activity in multiple myeloma and beneficial effect on bone density.

12 Dec 2011

Ovary removal in younger women may lead to low-bone mineral density, arthritis

Having both ovaries removed before age 45 is strongly associated with low-bone mineral density and arthritis in later years, according to a new study by Johns Hopkins oncologists and epidemiologists. The analysis covered several thousand women who took part in a U.S. government-sponsored, multiyear national health study, and excluded women whose ovaries were removed due to cancer.

9 Dec 2011

Zoledronic acid increases bone mineral density, reduces recurrence in postmenopausal breast cancer

The addition of zoledronic acid to adjuvant endocrine therapy increased bone mineral density and reduced the risk for disease recurrence among postmenopausal women with early hormone receptor-positive breast cancer, according to new data from the ZO-FAST trial.

8 Dec 2011

Unigene acquires exclusive worldwide rights to oral PTH program from GSK

Unigene Laboratories, Inc. today announced that the Company terminated its amended and restated exclusive worldwide license agreement and related development services and clinical supply agreement with GlaxoSmithKline (GSK) pertaining to an oral formulation of a recombinantly produced parathyroid hormone (PTH) analog for the treatment of osteoporosis in postmenopausal women.

5 Dec 2011

Growth hormone replacement increases bone formation in abdominally obese women

In a new study presented today at the annual meeting of the Radiological Society of North America (RSNA), growth hormone replacement for six months was found to increase bone formation in abdominally obese women.

29 Nov 2011

Omega-3 linked with reduced joint pain and cognitive side effects of breast cancer therapy

"I know I need this medicine to help lower my chance of cancer recurrence, but it makes my joints ache and stiff. It makes me feel old and I am not sure I can take this medication much longer."

19 Nov 2011

Obese premenopausal women may benefit from dairy food consumption

A recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM) found that consumption of dairy foods and higher protein resulted in improvements in markers of bone formation and reductions in markers of bone degradation in overweight and obese young women over 16 weeks of diet- and exercise-induced weight loss.

10 Nov 2011

DuoCort Pharma granted marketing authorization for adrenal insufficiency drug, Plenadren in Europe

The Swedish specialty pharma company, DuoCort Pharma, announced today that the European Commission has granted a European Marketing Authorisation for Plenadren (hydrocortisone, modified release tablet), an orphan drug for treatment of adrenal insufficiency in adults, bringing these patients their first pharmaceutical innovation in over 50 years.

7 Nov 2011

Many spinal fusion surgery patients have low levels of vitamin D

A new study indicates that many patients undergoing spine surgery have low levels of vitamin D, which may delay their recovery. In a study of 313 patients undergoing spinal fusion surgery, orthopaedic surgeons at Washington University School of Medicine in St. Louis found that more than half had inadequate levels of vitamin D, including one-fourth who were more severely deficient.

3 Nov 2011

Bone Mineral Density News and Research

DXA scan should be done at shorter intervals for women at high risk for fracture

Mechanical dose of load through muscle force may slow bone loss in SCI patients

Genzyme announces four-year data from eliglustat tartrate phase 2 trial on Gaucher disease type 1

Exemestane has negative effect on postmenopausal women's bone health

Heart failure associated with 30% increase in major fractures

Research roundup: 'No individual mandate' scenarios; Breaking down health care expenditures

Testing for osteoporosis – how often?

Women aged 67 years with normal bone mineral density may not need screening again for 15 years

Gilead Sciences receives FDA approval for Viread to treat pediatric HIV infection

FRAX tool now available as version 3.5 in 18 languages

Physician notification system can help prevent further fractures in osteoporotic patients

BioInvent announces new BI-505 preclinical data on multiple myeloma

Ovary removal in younger women may lead to low-bone mineral density, arthritis

Zoledronic acid increases bone mineral density, reduces recurrence in postmenopausal breast cancer

Unigene acquires exclusive worldwide rights to oral PTH program from GSK

Growth hormone replacement increases bone formation in abdominally obese women

Omega-3 linked with reduced joint pain and cognitive side effects of breast cancer therapy

Obese premenopausal women may benefit from dairy food consumption

DuoCort Pharma granted marketing authorization for adrenal insufficiency drug, Plenadren in Europe

Many spinal fusion surgery patients have low levels of vitamin D

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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How Omics Technologies Are Transforming Biological Research and Drug Discovery

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