Brain Cancer News and Research

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There are two main types of brain cancer. Primary brain cancer starts in the brain. Metastatic brain cancer starts somewhere else in the body and moves to the brain. Brain tumors can be benign, with no cancer cells, or malignant, with cancer cells that grow quickly. Also called glioma, meningioma.

Finding new clues to combat glioblastoma

Glioblastoma is an aggressive, killer disease. While victims of this fast-moving brain tumor comprise only about 15% of all people with brain cancer, its victims rarely survive more than a few years after diagnosis.

20 Feb 2020

Researchers design new drug cocktail to kill brain and soft tissue cancers

Researchers at the USC Viterbi School of Engineering have designed a new drug cocktail that kills some types of brain and soft tissue cancers by tricking the cancer cells to behave as if they were starving for their favorite food--glucose.

20 Feb 2020

Combination therapy for pediatric low-grade gliomas shows promise in mice

In experiments with human cells and mice, researchers at the Johns Hopkins Kimmel Cancer Center report evidence that combining the experimental cancer medication TAK228 (also called sapanisertib) with an existing anti-cancer drug called trametinib may be more effective than either drug alone in decreasing the growth of pediatric low-grade gliomas.

17 Feb 2020

Scientists pinpoint protein that plays key role in lung cancer and melanoma progression

Scientists from Far Eastern Federal University, University of Geneva (Switzerland), Minjiang University, and Fuzhou University (China) pointed out WDR74 protein playing an important role in lung cancer and melanoma primary tumors/metastases progression.

16 Feb 2020

Surprising discovery about childhood brain tumor may unlock new cancer treatments

A surprising discovery about a rare form of childhood brain cancer suggests a new treatment approach for that cancer and, potentially, many others.

13 Feb 2020

Finding a cure for canine gliomas may help find treatment for human brain cancer

Cancer research using experimental models--everything from cancer cells in a dish to patient tumors transplanted in mice--has been extremely useful for learning more about the disease and how we might treat it.

10 Feb 2020

Researchers culture human blood-brain barrier on a chip

A scrupulous gatekeeper stands between the brain and its circulatory system to let in the good and keep out the bad, but this porter, called the blood-brain barrier, also blocks trial drugs to treat diseases like Alzheimer's or cancer from getting into the brain.

10 Feb 2020

Multimodal analysis of tumors could give new insights into treating cancer patients

Melding the genetic and cellular analysis of tumors with how they appear in medical images could give physicians and other cancer therapy specialists new insights into how to best treat patients, especially those with brain cancer, according to a new study led by the Translational Genomics Research Institute, an affiliate of City of Hope.

31 Jan 2020

Buck study uncovers how astrocyte senescence promotes neurodegeneration

Although a link has been established between chronic inflammation and neurodegenerative diseases, there have been many open questions regarding how cellular senescence, a process whereby cells that stop dividing under stress spew out a mix of inflammatory proteins, affects these pathologies.

29 Jan 2020

New strategy using organoids to study childhood brain tumors

A new study reports the creation of in vitro models of brain tumors in children using organoids derived from stem cells, which will help to screen new drugs for efficacy and thus improve the rate of drug development. The study, titled 'Modeling medulloblastoma in vivo and with human cerebellar organoids,' is published in the journal Nature Communications.

29 Jan 2020

Researchers develop new strategy to study childhood brain tumors

Researchers are at work to find effective treatments to help young patients with brain tumors. Hundreds of brain organoids have been developed in the laboratories of the University of Trento to understand the genetic mechanisms responsible for these hard to treat diseases.

29 Jan 2020

Researchers create new brain cancer model using genetically engineered pluripotent stem cells

Using genetically engineered human pluripotent stem cells, University of California San Diego School of Medicine researchers created a new type of cancer model to study in vivo how glioblastoma, the most common and aggressive form of brain cancer, develops and changes over time.

29 Jan 2020

Exploring link between elevated blood pressure early in life and dementia

Whether elevated blood pressure early in life translates to increased risk of dementia is a question scientists are working to answer.

28 Jan 2020

A menu of treatments for glioblastoma

Sara Piccirillo, PhD, is passionate about finding a way to beat glioblastoma, the most aggressive type of brain cancer.

23 Jan 2020

International researchers confirm potential inhibitors to combat glioblastoma

After diagnosis, only thirty percent of glioblastoma (an aggressive brain cancer) patients have survived more than two years.

21 Jan 2020

'Innovative Research Award' helps CU scientists to explore BRAF inhibition resistance in brain cancer

Cancers used to be defined by where they grow in the body - lung cancer, skin cancer, brain cancer, etc. But work in recent decades has shown that cancers sharing specific genetic changes may have more in common than cancers that happen to grow in an area of the body.

21 Jan 2020

Improved microfluidic brain chip can assess the effectiveness of cancer drugs in record time

The Akay Lab biomedical research team at the University of Houston is reporting an improvement on a microfluidic brain cancer chip previously developed in their lab.

17 Jan 2020

Discovery of mechanism by which Zika virus enters brain cells

Two independent studies published by Cell Press on January 16, 2020, report that the mechanism by which Zika virus enters brain cells has been identified and even more, exploited to prevent Zika infection and to kill cancer cells instead.

16 Jan 2020

Surgical removal of tumor may boost survival of patients with brainstem high-grade gliomas

For adult patients with brainstem high-grade gliomas -- one of the rarest and deadliest forms of brain cancer -- surgically removing the entire tumor may add many months or potentially years of survival beyond that offered by radiation and chemotherapy, according to results of a medical records study led by researchers at the Johns Hopkins Kimmel Cancer Center.

From Johns Hopkins Medicine 9 Jan 2020

New brain tumor research could improve patient diagnosis, treatment options

New research on brain tumours could improve patient diagnosis and treatment options as part of a precision medicine approach. Brain tumours are the leading cause of cancer deaths in children and adults under the age of 40, with 16,000 people in the UK diagnosed with a brain tumour each year.

7 Jan 2020

Brain Cancer News and Research

Further Reading

Finding new clues to combat glioblastoma

Researchers design new drug cocktail to kill brain and soft tissue cancers

Combination therapy for pediatric low-grade gliomas shows promise in mice

Scientists pinpoint protein that plays key role in lung cancer and melanoma progression

Surprising discovery about childhood brain tumor may unlock new cancer treatments

Finding a cure for canine gliomas may help find treatment for human brain cancer

Researchers culture human blood-brain barrier on a chip

Multimodal analysis of tumors could give new insights into treating cancer patients

Buck study uncovers how astrocyte senescence promotes neurodegeneration

New strategy using organoids to study childhood brain tumors

Researchers develop new strategy to study childhood brain tumors

Researchers create new brain cancer model using genetically engineered pluripotent stem cells

Exploring link between elevated blood pressure early in life and dementia

A menu of treatments for glioblastoma

International researchers confirm potential inhibitors to combat glioblastoma

'Innovative Research Award' helps CU scientists to explore BRAF inhibition resistance in brain cancer

Improved microfluidic brain chip can assess the effectiveness of cancer drugs in record time

Discovery of mechanism by which Zika virus enters brain cells

Surgical removal of tumor may boost survival of patients with brainstem high-grade gliomas

New brain tumor research could improve patient diagnosis, treatment options

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