Embryonic Stem Cell News and Research

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Thymosin beta 4 can transform adult epicardial stem cells into functional heart muscle

RegeneRx Biopharmaceuticals, Inc. has announced that thymosin beta 4 (Tβ4) can activate a unique subpopulation of resident adult epicardial stem cells such that they recapture embryonic potential, proliferate, migrate and differentiate into functional heart muscle (cardiomyocytes), according to a research paper published online today in Nature.

9 Jun 2011

Article reports on bright future and enormous need for stem cell therapeutics

An article in the current issue of Technology & Innovation, Proceedings of the National Academy of Inventors - reports on the bright future and enormous need for stem cell therapeutics that may offer hope for those suffering from debilitating and deadly diseases.

9 Jun 2011

Geron's GRNOPC1 Phase 1 trial results on spinal cord injury presented at international conferences

Geron Corporation today announced two presentations on the company's ongoing Phase 1 clinical trial of the human embryonic stem cell-based therapy, GRNOPC1, in patients with spinal cord injury.

7 Jun 2011

NIH approves BioTime's two human embryonic stem cell lines for clinical use

BioTime, Inc., a biotechnology company that develops and markets products in the field of regenerative medicine, today announced that two human embryonic stem (hES) cell lines, ESI-014 and ESI-017, developed by a BioTime subsidiary have been approved by the National Institutes of Health (NIH) for inclusion in the NIH Human Embryonic Stem Cell Registry.

4 Jun 2011

Scientists add four proteins to skin cells to create functional neurons

The New York Stem Cell Foundation - a non-profit organization dedicated to advancing cures for major diseases through stem cell research - today applauded the announcement by Stanford University scientists, led by NYSCF - Robertson Investigator Dr. Marius Wernig, that they directly converted skin cells of humans into functional neurons.

27 May 2011

Stem cell pluripotency depends on E-cadherin molecule

Researchers of the Max Delbr-ck Center for Molecular Medicine (MDC) Berlin-Buch have discovered what enables embryonic stem cells to differentiate into diverse cell types and thus to be pluripotent. This pluripotency depends on a specific molecule - E-cadherin - hitherto primarily known for its role in mediating cell-cell adhesion as a kind of "intracellular glue".

27 May 2011

Researchers convert human skin cells directly into functional neurons within four to five weeks

Human skin cells can be converted directly into functional neurons in a period of four to five weeks with the addition of just four proteins, according to a study by researchers at the Stanford University School of Medicine.

27 May 2011

Longer looks: Stem cells, vaccinating against addictive drugs, the GOP's budget hatchet man

Krista and Tatiana are not like most other sets of twins. They are connected at their heads, where their skulls merge under a mass of shaggy brown bangs. The girls run and play and go down their backyard slide, but whatever they do, they do together, their heads forever inclined toward each other's, their neck muscles strong and sinuous from a never-ending workout. Twins joined at the head — the medical term is craniopagus — are extremely rare.

27 May 2011

Scientists mimic dyskeratosis congenita through study of undifferentiated iPS cells

A rare genetic disease called dyskeratosis congenita, caused by the rapid shortening of telomeres, can be mimicked through the study of undifferentiated induced pluripotent stem cells, according to new findings from the Stanford University School of Medicine.

24 May 2011

ISCO enrolls first U.S.-based donor to establish clinical-grade human parthenogenetic stem cell bank

International Stem Cell Corporation has now enrolled the first U.S.-based donor in its program to establish a bank of clinical-grade human parthenogenetic stem cells (hpSCs) capable of being immune-matched to millions of patients.

19 May 2011

Stem cells from kidneys - World first from Australian scientists

According to Australian scientists, their latest stem cell research breakthrough will bring new treatments for a growing epidemic of chronic kidney disease. They are the first in the world to generate a type of stem cell from human kidney cells. The Melbourne scientists are hoping their discovery will have far-reaching effects in treating the disease.

19 May 2011

Scientists nail mechanism causing embryonic stem cells to differentiate into specialised cells

A team led by developmental biologist Professor Christophe Marcelle has nailed the mechanism that causes stem cells in the embryo to differentiate into specialised cells that form the skeletal muscles of animals' bodies.

18 May 2011

Scientists make human stem cells without working on human embryos

Stem cell research courts both controversy and support in the community- depending on your viewpoint.

17 May 2011

Study provides evidence that adult planarians harbor pluripotent stem cells

A single adult cell from one of the most impressive masters of regeneration in the animal kingdom - the planarian - is all it takes to build a completely functional new worm, researchers have learned. The study provides the first hard evidence that adult planarians harbor pluripotent stem cells - cells capable of producing the diverse range of tissue types necessary to build a complete animal.

13 May 2011

iPSC-derived liver cells hold potential as alternative to liver transplants

Johns Hopkins researchers have demonstrated that human liver cells derived from adult cells coaxed into an embryonic state can engraft and begin regenerating liver tissue in mice with chronic liver damage.

12 May 2011

Second subject enrolled in human embryonic stem cell therapy trial for subacute thoracic spinal cord injury

Researchers at Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine and The Rehabilitation Institute of Chicago (RIC) recently enrolled their first subject in a national clinical research trial of a human embryonic stem cell-based therapy for participants with a subacute thoracic spinal cord injury.

11 May 2011

UCSF scientists receive CIRM grants to advance degenerative muscle disease research

Three UCSF scientists have received grants from the California Institute for Regenerative Medicine to advance their investigations of treatment strategies for degenerative muscle diseases, such as muscular dystrophy, and heart disease, and to determine why human embryonic stem cells are susceptible to forming tumors.

10 May 2011

Three Ontario projects set to further knowledge and discovery in biomonitoring, drug development

As part of the Genome Canada Large-Scale Applied Research Project Competition, which as a whole awarded over $58 million to 16 projects across the country, the researchers in Ontario will be focusing on biomonitoring, understanding gene function with the aim of identifying genes or proteins for drug targets, and the creation of synthetic antibodies to target cancers and other diseases.

9 May 2011

Advanced Cell Technology first quarter net loss decreases to $3.3 million

Advanced Cell Technology, Inc., a leader in the field of regenerative medicine, announced today first quarter financial results for the period ended March 31, 2011. The Company reported a loss from operations of $(4.8) million compared to a loss from operations of $(15.0) million in the 2010 first quarter.

9 May 2011

UCSF scientists elected as members of National Academy of Sciences for excellence in biomedical research

Alexander D. Johnson, PhD, and Shinya Yamanaka, MD, PhD, have been elected as members of the National Academy of Sciences for their excellence in original scientific research. It is one of the highest honors bestowed on a scientist or engineer in the United States.

5 May 2011

Embryonic Stem Cell News and Research

Thymosin beta 4 can transform adult epicardial stem cells into functional heart muscle

Article reports on bright future and enormous need for stem cell therapeutics

Geron's GRNOPC1 Phase 1 trial results on spinal cord injury presented at international conferences

NIH approves BioTime's two human embryonic stem cell lines for clinical use

Scientists add four proteins to skin cells to create functional neurons

Stem cell pluripotency depends on E-cadherin molecule

Researchers convert human skin cells directly into functional neurons within four to five weeks

Longer looks: Stem cells, vaccinating against addictive drugs, the GOP's budget hatchet man

Scientists mimic dyskeratosis congenita through study of undifferentiated iPS cells

ISCO enrolls first U.S.-based donor to establish clinical-grade human parthenogenetic stem cell bank

Stem cells from kidneys - World first from Australian scientists

Scientists nail mechanism causing embryonic stem cells to differentiate into specialised cells

Scientists make human stem cells without working on human embryos

Study provides evidence that adult planarians harbor pluripotent stem cells

iPSC-derived liver cells hold potential as alternative to liver transplants

Second subject enrolled in human embryonic stem cell therapy trial for subacute thoracic spinal cord injury

UCSF scientists receive CIRM grants to advance degenerative muscle disease research

Three Ontario projects set to further knowledge and discovery in biomonitoring, drug development

Advanced Cell Technology first quarter net loss decreases to $3.3 million

UCSF scientists elected as members of National Academy of Sciences for excellence in biomedical research

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