Glucose Metabolism News and Research

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Naturally occurring molecule could improve brain metabolism in patients with MS

N-acetylcysteine is a naturally occurring molecule that replenishes antioxidants and shows improved brain metabolism and self-reported improvements in cognitive function in patients with multiple sclerosis, according to a study published in the journal, Frontiers in Neurology.

26 Feb 2020

Researchers uncover how cancer cells override environmental cues to consume energy

Using human lung cancer cells, UT Southwestern researchers have uncovered how cells in general modulate their energy consumption based on their surroundings and, furthermore, how cancer cells override those cues to maximize energy use.

24 Feb 2020

Researchers say ‘yes’ to a heavy breakfast to lose weight

There has been some debate on whether or not to pile up on calories at the first meal of the day. According to German researchers, to lose weight, one must eat a healthy and hearty breakfast.

20 Feb 2020

Understanding the genetic background of idiopathic ketotic hypoglycemia

Lisa is two years old. She often gets uneasy--shaking and sweating--especially in the morning. She vomits and refuses to eat. Her mother, Karoline, knows she has to act before Lisa starts to deteriorate.

9 Feb 2020

Regular aerobic exercise could enhance cognitive functions in adults at risk for Alzheimer’s

Individuals at risk for Alzheimer's disease (AD) because of family history or genetic predisposition who engaged in six months of aerobic exercise training improved their brain glucose metabolism and higher-order thinking abilities (e.g., planning and mental flexibility) called executive function; these improvements occurred in conjunction with increased cardiorespiratory fitness.

3 Feb 2020

Novel drug inhibits liver damage, obesity and glucose intolerance in mice fed with high-fat diet

Mice given a new drug targeting a key gene involved in lipid and glucose metabolism could tolerate a high-fat diet regimen (composed of 60% fat from lard) without developing significant liver damage, becoming obese, or disrupting their body's glucose balance.

20 Jan 2020

Experimental Alzheimer’s drugs show promise

Researchers from Salk have found that two experimental drugs named CMS121 and J147 may improve memory functions and reduce the progression of memory decline and brain degeneration in mice models of Alzheimer’s disease (AD). The researchers published their work in the latest issue of the journal eLife. The study was titled, “Elevating acetyl-CoA levels reduces aspects of brain aging.”

11 Dec 2019

Collaborative Frontiers grant to help predict behavior of the brain under metabolic stress

More than 30 million Americans have diabetes, with the vast majority having Type 2 disease. Characterized by insulin resistance and persistently high blood sugar levels, poorly controlled Type 2 diabetes has a host of well-recognized complications: compared with the general population, a greatly increased risk of kidney disease, vision loss, heart attacks and strokes, and lower limb amputations.

11 Dec 2019

Early-morning, starch-rich meal improves glycemic control among type 2 diabetics

Type 2 diabetics inject themselves with insulin, a hormone that regulates the movement of sugar into liver, muscle and fat cells, up to four times a day. But insulin injections are linked to weight gain and the loss of control of blood sugar levels. This triggers a vicious cycle of higher insulin doses, continuous weight gain, a higher incidence of cardiovascular disease and other complications.

3 Dec 2019

Hops compounds may combat metabolic syndrome by changing the gut microbiome

Compounds from hops may combat metabolic syndrome by changing the gut microbiome and altering the metabolism of acids produced in the liver, new research at Oregon State University suggests.

26 Nov 2019

New drug combo may improve pancreatic cancer therapy

A new study by scientists at Sanford Burnham Prebys Medical Discovery Institute have discovered a combination of two cancer-fighting drugs that successfully worked on pancreatic tumor in mice, shrinking them significantly, and paving the way for a speedy clinical trial designed to test their efficacy in humans.

18 Nov 2019

Medical steroid use could push up diabetes risk

Glucocorticoids (GCs), or steroids, as they are popularly called, are often prescribed for their anti-inflammatory effects in a host of conditions including acute asthmatic attacks, allergies, and arthritis. However, are they doing good or harm?

12 Nov 2019

Hyperthyroidism and severe hypothyroidism associated with overall unhealthy status, shorter lifespan

Herein, the authors show, using wild-type and the Pax8 ablated model of hypothyroidism in mice, that hyperthyroidism and severe hypothyroidism are associated with an overall unhealthy status and shorter lifespan.

3 Oct 2019

Sleep deprivation affects fat metabolism

We're all a little short on sleep during the work week. A new study adds to the mounting evidence about just how harmful lack of sleep can be.

16 Sep 2019

Psychopathy associated with robust alterations in expression of genes, study shows

The expression of many genes that have previously been associated with autism is abnormal also in violent psychopathy, a new study shows.

30 Aug 2019

Researchers illuminate mysterious aspect of mitochondrial metabolism using a tiny thermometer

Armed with a tiny new thermometer probe that can quickly measure temperature inside of a cell, University of Illinois researchers have illuminated a mysterious aspect of metabolism: heat generation.

30 Aug 2019

Potential drug could revolutionize the treatment of neurological conditions

The international team of scientists from Gero Discovery LLC, the Institute of Biomedical Research of Salamanca, and Nanosyn, Inc. has found a potential drug that may prevent neuronal death through glucose metabolism modification in stressed neurons.

28 Aug 2019

Fish oils have little or no effect on risk of Type 2 diabetes

Omega-3 fats have little or no effect on risk of Type 2 diabetes according to new research from the University of East Anglia.

22 Aug 2019

Women with diabetes at greater risk for sleep disturbances

Hormone changes are known to alter insulin sensitivity and glucose metabolism, as well as interfere with women's sleep patterns.

14 Aug 2019

Liver function may be important in Alzheimer’s disease risk

A new study shows a strong link between altered liver function and the development of Alzheimer’s disease (AD). This correlates with recent data on the role played by diseases affecting the systemic metabolism, such as diabetes and high blood cholesterol, in disruptions of brain function as in AD.

31 Jul 2019