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Emerging PPAR therapies offer new hope for primary biliary cholangitis

Primary biliary cholangitis is a rare autoimmune disease that affects the liver and can progress to cirrhosis. It occurs when the immune system attacks the small bile ducts within the liver. As a result, bile builds up, leading to inflammation and progressive liver damage. Although a first-line treatment exists, 40% of patients do not respond adequately to it or cannot tolerate it, so new treatment options need to be developed.

23 Jul 2026

Study reveals bacterial strategy behind antibiotic tolerance and persistence

Antibiotics are a medical marvel, but many microbes are gaining the ability to resist and tolerate these therapeutics.

22 Jul 2026

Senolytic drugs rejuvenate blood stem cells in sickle cell disease

Sickle cell disease causes premature aging of blood stem cells, which scientists may be able to address with a special class of drugs, according to a new study from St. Jude Children's Research Hospital.

22 Jul 2026

Racial and geographic disparities continue affecting stroke treatment outcomes

Three studies presented today at the Society of NeuroInterventional Surgery's (SNIS) 23rd Annual Meeting found that racial, geographic and socioeconomic disparities continue to influence stroke treatment and outcomes across the United States.

22 Jul 2026

Experimental neurointerventional technique shows promise for severe back pain

Researchers at the Society of NeuroInterventional Surgery (SNIS) 23rd Annual Meeting presented an experimental neurointerventional technique designed to treat severe back pain, a leading cause of disability and opioid use, by delivering medication directly through the arteries supplying the painful area.

22 Jul 2026

Gut immune cells may improve multiple sclerosis treatment outcomes

B-cell depletion therapies, in which B cells of the immune system, which may drive disease activity in multiple sclerosis (MS), are temporarily removed, have contributed significantly to improved treatment for patients in recent years.

22 Jul 2026

Handheld breathalyzer enables precise monitoring of fat metabolism

Researchers from ETH Zurich have developed a portable measuring device that detects the metabolic marker acetone in breath almost as accurately as a mass spectrometer.

22 Jul 2026

New study uses sleep monitoring and AI to detect Alzheimer's

Researchers from Universidad Carlos III de Madrid (UC3M) and Hospital Universitario Severo Ochoa in Leganés, part of the public health network of the Comunidad de Madrid, have developed a methodology that uses artificial intelligence (AI) to analyze brain electrical activity during sleep and facilitate the early diagnosis of Alzheimer's.

22 Jul 2026

Study: Why First Nations children still face health care inequalities

A new study finds that First Nations Children still face long-standing inequalities in health care access in Canada despite improvements made through the application of Jordan's Principle - a policy designed to ensure First Nations children receive the services they need.

22 Jul 2026

Understanding the role of cerebral venous flow in idiopathic intracranial hypertension

Idiopathic intracranial hypertension (IIH) is a rare and poorly understood neurological disorder that affects 1 to 20 people per 100,000-most often women of childbearing age.

22 Jul 2026

Corn-based foods linked to higher mycotoxin exposure in pregnancy

Consuming common foods such as corn chips and popcorn may put pregnant women at risk of being exposed to mycotoxins – harmful substances produced by mold – according to Rutgers researchers.

22 Jul 2026

Newer GLP-1 medications may reduce alcohol-related hospitalization risk

Use of newer GLP-1 receptor agonists (semaglutide or tirzepatide) for obesity or diabetes by people with alcohol-use disorder was associated with a reduction in alcohol-related admissions to hospital, finds a study published online in the open access journal BMJ Open.

21 Jul 2026

New blood test improves colorectal cancer recurrence risk prediction

A single preoperative blood sample may help improve the prediction of recurrence or metastasis in patients with colorectal cancer.

21 Jul 2026

New ARPA-H grant aims to advance genomic medicines for rare vascular diseases

Massachusetts General Hospital, a founding member of the Mass General Brigham healthcare system, has been awarded an Advanced Research Projects Agency for Health (ARPA-H) contract to develop advanced personalized genomic medicines to treat rare genetic vascular diseases.

21 Jul 2026

Swimming can be clinically effective in reducing disability from chronic low back pain

Australian research has shown for the first time that a program of swimming can be clinically effective in reducing disability from chronic low back pain.

21 Jul 2026

Common heart risk calculators effectively predict certain types of cancer

Risk calculators that doctors use to estimate a person's risk of a heart attack or stroke work about as well for predicting certain cancers, according to a new study by UCL (University College London) researchers.

21 Jul 2026

New AI framework prioritizes high quality patient care in hospitals

A UVA Health emergency medicine doctor and colleague at Clemson University have developed a framework to help hospitals integrate artificial intelligence to not just increase efficiency and cut costs but ensure high-quality patient care remains the top priority.

21 Jul 2026

Mount Sinai establishes new autoimmunity center with $5 million gift

A $5 million gift from philanthropists Judith and Stewart Colton will establish a Colton Center for Autoimmunity within the Marc and Jennifer Lipschultz Precision Immunology Institute (PrIISM) at the Icahn School of Medicine at Mount Sinai.

21 Jul 2026

Childhood unpredictability linked to higher mental health risks

Children who grow up in unpredictable environments may face elevated risks for depression, anxiety, sleep disorders and other mental health challenges, according to a new study by researchers at the University of California, Irvine, Chapman University and Rady Children's Hospital Orange County, formerly called Children's Hospital of Orange County.

21 Jul 2026

Tailored gene therapy dramatically reduces childhood epilepsy seizures in trial

SCN2A‑related developmental epileptic encephalopathy (DEE) is a rare, severe form of childhood epilepsy and one of the most common causes of monogenic autism.

21 Jul 2026