Methadone News and Research

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Novartis' Tasigna capsules meets primary endpoint in comparison trial with Gleevec

Novartis announced today that Tasigna (nilotinib) 200 mg capsules met its primary endpoint in the first head-to-head comparison with the company's groundbreaking drug Gleevec (imatinib mesylate) tablets*. Tasigna produced faster and deeper responses than Gleevec when given as first-line therapy for adult patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) in chronic phase. Tasigna was well tolerated in the study.

20 Oct 2009

Vaccine to treat cocaine dependence reduces use of the drug, according to study

A vaccine to treat cocaine dependence appears to reduce use of the drug in a subgroup of individuals who attain high anticocaine antibody levels in response, according to a report in the October issue of Archives of General Psychiatry, one of the JAMA/Archives journals. However, only 38 percent of vaccinated individuals produced high enough antibody levels and those who did maintained them for only two months.

6 Oct 2009

Mountain Lakes to implement Netsmart's clinical and practice management behavioral health software solution

Netsmart Technologies, Inc., a leading provider of software and services for health and human services organizations, today announced an agreement to provide its CCHIT-certified clinical and practice management behavioral health software and related services to Mountain Lakes Behavioral Healthcare of Guntersville, Ala

24 Sep 2009

Phase III STARTMRK clinical study on ISENTRESS in comparison to efavirenz

ISENTRESS , an integrase inhibitor from Merck & Co., Inc., was studied in comparison to efavirenz in maintaining viral load suppression to undetectable levels (less than 50 copies/mL) and at improving CD4 cell counts in previously untreated (treatment-naïve) HIV-1-infected patients through 96 weeks in a Phase III study called STARTMRK.

14 Sep 2009

ORT remains underutilized in U.S. prison systems

Almost a quarter of a million individuals addicted to heroin are incarcerated in the United States each year. However, many prison systems across the country still do not offer medical treatment for heroin and opiate addiction, despite the demonstrated social, medical and economic benefits of opiate replacement therapy (ORT).

9 Sep 2009

Cocaine and heroin increase permeability of the placenta

Cocaine and heroin increase permeability of the placenta. Researchers writing in BioMed Central's open access journal Reproductive Biology and Endocrinology have shown that exposure to the drugs causes an increase in the passage of some chemicals into the fetus.

10 Jun 2009

Thai HIV/AIDS advocates urge increased treatment access for IDUs

The Thai AIDS Treatment Action Group recently called on the country to launch a comprehensive harm reduction program for injection drug users in an effort to help curb the spread of HIV, Thailand's The Nation reports.

31 May 2009

Double the number of Australians now being treated for heroin addiction

The latest report from the Australian Institute of Health and Welfare (AIHW) shows in the last decade the number of Australians being treated for heroin, or other opioid, addiction has almost doubled.

22 May 2009

About 20% of surveyed sex workers who use drugs in Irish capital living with HIV, report finds

About one-fifth of commercial sex workers surveyed in Dublin, Ireland, are HIV-positive, while 78% of the surveyed group is living with hepatitis C, according to a report released Tuesday by the National Advisory Committee on Drugs, the Irish Times reports.

14 May 2009

New initiative to ensure the safe use of methadone

The U.S. Substance Abuse and Mental Health Services Administration (SAMHSA) and the U.S. Food and Drug Administration (FDA) has launched an initiative to help ensure the safe use of methadone.

30 Apr 2009

Discovery of new mechanism for the processing of endocannabinoids

New research funded by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, has identified a new mechanism for the processing of endocannabinoids, natural brain compounds similar to THC, the active ingredient in marijuana.

17 Mar 2009

University at Buffalo designed ventilator can safely sedate ICU patients for less

A new, recently licensed medical device developed by University at Buffalo researchers would introduce into intensive care settings the powerful and effective method of anesthetizing patients that works so well in the operating room.

25 Feb 2009

Ondansetron shown to be a viable treatment option for opioid addiction

Scientists at Stanford University School of Medicine have discovered that a commonly available non-addictive drug can prevent symptoms of withdrawal from opioids with little likelihood of serious side effects.

18 Feb 2009

Medical prescription of heroin does not pose neighborhood risk

Providing heroin to drug addicts at medically supervised clinics does not pose risks to surrounding neighbourhoods, according to a new study by Serge Brochu, a researcher at the Université de Montréal School of Criminology.

18 Feb 2009

Girls growing up with heroin-addicted parent more resilient than boys

Growing up with a heroin-addicted parent exposes children to a variety of detrimental experiences before the age of 18 and new research indicates that girls are four times more resilient than boys in overcoming such adverse events.

11 Feb 2009

A new method to detect presence of 23 illicit drugs

A team of scientists from the Institute of Legal Medicine at the University of Santiago de Compostela (USC) has developed a technique for detecting the presence of 23 illicit drugs and medicines in saliva samples.

11 Feb 2009

New guidelines for prescribing opioid pain drugs

A prestigious panel of pain-management experts representing the American Pain Society (APS) www.ampainsoc.org and the American Academy of Pain Medicine (AAPM) has published the first comprehensive clinical practice guideline to assist clinicians in prescribing potent opioid pain medications for patients with chronic non-cancer pain.

10 Feb 2009

New guideline for prescribing opioid pain drugs published

A national panel of pain management experts representing the American Pain Society (APS) and the American Academy of Pain Medicine (AAPM) has published the first comprehensive, evidence-based clinical practice guideline to assist clinicians in prescribing potent opioid pain medications for patients with chronic non-cancer pain.

8 Feb 2009

Recovery coaches reduce the number of babies exposed to drugs

Of the 4 million babies born in the United States each year around 11% have been exposed to alcohol or illicit drugs in the womb.

6 Jan 2009

Australian children under 15 twice as likely to be murdered than UK children

A study into the circumstances surrounding the murders of children in New South Wales between 1991 to 2005 has revealed some shocking and disturbing information.

5 Jan 2009