Prostate Specific Antigen News and Research

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Research roundup: Ameliorating physician shortages; Patients' perceptions of bias

The authors note that there is a consensus "that the current shortage of primary care physicians will worsen over the next ten years as the nation's population grows and ages and as insurance coverage expands as a result of the Affordable Care Act." They examine whether workplace changes will impact that assessment.

19 Jan 2013

Partin Tables to predict prostate cancer spread now updated

Prostate cancer experts at Johns Hopkins have developed an updated version of the Partin Tables, a tool to help men diagnosed with prostate cancer and their doctors to better assess their chance of a surgical cure. The updated tool, based on a study of more than 5,600 men treated at The Johns Hopkins Hospital from 2006 to 2011, is published in the Jan. 3 issue of the British Journal of Urology International.

3 Jan 2013

Active surveillance of prostate cancer patients encouraged

Active surveillance is an effective way of monitoring patients with low-risk prostate cancer and is associated with a low risk for systemic progression, say researchers.

31 Dec 2012

MRI fused with ultrasound to strengthen prostate cancer diagnosis

Researchers have developed a technique that fuses magnetic resonance imaging with ultrasound to improve the detection and treatment of prostate cancer.

24 Dec 2012

Researchers develop game-changing diagnostic and prognostic genetic tests for prostate cancer

Researchers at the Kimmel Cancer Center at Jefferson (KCC) have developed potentially game-changing diagnostic and prognostic genetic tests shown to better predict prostate cancer survival outcomes and distinguish clinically-relevant cancers.

21 Dec 2012

Abiraterone improves outcomes for prostate cancer prior to chemo

Treatment with abiraterone acetate, an androgen biosynthesis inhibitor, may benefit patients with progressive metastatic castration-resistant prostate cancer who have not yet undergone chemotherapy, report researchers.

17 Dec 2012

New diagnostic innovations could refine the way doctors detect prostate cancer

Despite the volume of prostate cancer tests and treatments, experts and their patients are continually challenged to predict the disease's course and apply the most appropriate treatment. Now, two new diagnostic innovations – the PCA3 urine test and a more targeted prostate biopsy technique - could refine the way doctors diagnose prostate cancer and, subsequently, the way patients elect to treat it.

15 Dec 2012

Bayer files radium-223 NDA with FDA for treatment of CRPC patients with bone metastases

Bayer HealthCare today announced that the company has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) seeking approval for radium Ra 223 dichloride (radium-223), an investigational compound for the treatment of castration-resistant prostate cancer (CRPC) patients with bone metastases.

15 Dec 2012

MR-Ultrasound fusion biopsy can diagnose prostate cancer

Ground-breaking research by a UCLA team of physicians and engineers demonstrates that prostate cancer can be diagnosed using image-guided targeted biopsy.

11 Dec 2012

Magnetic resonance ultrasound fusion biopsy may improve prostate cancer diagnosis

Diagnosis of prostate cancer remains imperfect. Current methods of prostate biopsy are limited by over detection of slow-growing tumors and under detection of clinically relevant cancers. Investigators at the University of California-Los Angeles Department of Urology have found that a new technique of targeted biopsy in a clinic setting, using local anesthesia, may improve diagnosis and aid in selecting which patients are suitable for active surveillance and which need focal therapy (noninvasive techniques for destroying small tumors within the prostate).

11 Dec 2012

Dutasteride delays PSA progression

The 5α-reductase inhibitor, dutasteride, delays the clinical progression of prostate cancer in patients with prostate-specific antigen levels that have failed to reduce adequately following radical therapy for localized disease, report researchers.

28 Nov 2012

Mayo Clinic receives FDA approval for Choline C 11 Injection to help detect prostate cancer

Mayo Clinic has received U.S. Food and Drug Administration approval to produce and administer Choline C 11 Injection, an imaging agent used during a positron emission tomography (PET) scan to help detect sites of recurrent prostate cancer. Mayo Clinic is the first, and currently only, institution in North America approved to produce this imaging agent.

9 Nov 2012

Scientists develop new prototype ultra sensitive disease sensor

Scientists have developed a prototype ultra-sensitive sensor that would enable doctors to detect the early stages of diseases and viruses with the naked eye, according to research published today in the journal Nature Nanotechnology.

29 Oct 2012

Post-radiation drop in testosterone linked to recurrence of prostate cancer in men

Men whose testosterone drops following radiation therapy for prostate cancer are more likely to experience a change in PSA levels that signals their cancer has returned, according to new research from Fox Chase Cancer Center.

29 Oct 2012

Immediate postoperative radiation improves prostate cancer progression survival

Radiation immediately after prostate cancer surgery substantially improves biochemical progression-free survival and local control over 10 years compared with a wait-and-see policy, European study findings indicate.

22 Oct 2012

Long-term multivitamin use associated with prevention of cancer in middle-aged and older men

In a randomized trial that included nearly 15,000 male physicians, long-term daily multivitamin use resulted in a modest but statistically significant reduction in cancer after more than a decade of treatment and follow-up, according to a study appearing in JAMA.

19 Oct 2012

Routine screening influences outcomes in prostate cancer after surgery

Men who undergo radical prostatectomy for a tumor that was detected by screening show better long-term outcomes than their peers who undergo the surgery after opportunistic diagnosis, study results show.

3 Oct 2012

Increasing doses of radium chloride effective, tolerated in prostate cancer

Radium chloride treatment has dose-dependent beneficial effects on health outcomes in patients with castration-resistant prostate cancer and bone metastases, report researchers.

26 Sep 2012

Research roundup: 'Early' cost-control lessons from Mass.; Colonoscopy coverage; Impact of PSA recommendations

On Aug. 8, Massachusetts' third health care cost control bill became law. It "sets annual state spending targets, encourages the formation of accountable care organizations, and establishes an independent commission to oversee health care system performance."

21 Sep 2012

Mayo Clinic receives FDA approval for Choline C 11 Injection to help detect prostate cancer

The U.S. Food and Drug Administration today approved the production and use of Choline C 11 Injection, a Positron Emission Tomography (PET) imaging agent used to help detect recurrent prostate cancer.

13 Sep 2012

Prostate Specific Antigen News and Research

Research roundup: Ameliorating physician shortages; Patients' perceptions of bias

Partin Tables to predict prostate cancer spread now updated

Active surveillance of prostate cancer patients encouraged

MRI fused with ultrasound to strengthen prostate cancer diagnosis

Researchers develop game-changing diagnostic and prognostic genetic tests for prostate cancer

Abiraterone improves outcomes for prostate cancer prior to chemo

New diagnostic innovations could refine the way doctors detect prostate cancer

Bayer files radium-223 NDA with FDA for treatment of CRPC patients with bone metastases

MR-Ultrasound fusion biopsy can diagnose prostate cancer

Magnetic resonance ultrasound fusion biopsy may improve prostate cancer diagnosis

Dutasteride delays PSA progression

Mayo Clinic receives FDA approval for Choline C 11 Injection to help detect prostate cancer

Scientists develop new prototype ultra sensitive disease sensor

Post-radiation drop in testosterone linked to recurrence of prostate cancer in men

Immediate postoperative radiation improves prostate cancer progression survival

Long-term multivitamin use associated with prevention of cancer in middle-aged and older men

Routine screening influences outcomes in prostate cancer after surgery

Increasing doses of radium chloride effective, tolerated in prostate cancer

Research roundup: 'Early' cost-control lessons from Mass.; Colonoscopy coverage; Impact of PSA recommendations

Mayo Clinic receives FDA approval for Choline C 11 Injection to help detect prostate cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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