Stenosis News and Research

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A stenosis is an abnormal narrowing in a blood vessel or other tubular organ or structure.

Clinical trial finds COREVALVE reduces rate of death, stroke in patients with aortic stenosis

In a clinical trial, a self-expanding transcatheter aortic valve met the key performance objective of reducing death and stroke in patients with severe aortic stenosis at "extreme risk" for surgery.Results of the COREVALVE EXTREME RISK trial were presented today at the 25th annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium.

30 Oct 2013

Early morning SBP signals silent brain stenosis

Ambulatory systolic blood pressure in the early hours of the morning is predictive of asymptomatic intracranial arterial stenosis, the results of a cross-sectional study in China suggest.

28 Oct 2013

Stroke prevention study: Medication plus lifestyle changes safe, effective than surgical interventions

The final results of a stroke prevention study in patients with narrowed brain arteries confirm earlier findings: Medication plus lifestyle changes are safer and more effective at preventing stroke than a surgical technique called stenting.

28 Oct 2013

CSI receives PMA approval to market Diamondback 360 Coronary Orbital Atherectomy System

Cardiovascular Systems, Inc., today announced that it has received PMA approval from the U.S. Food and Drug Administration to market its Diamondback 360® Coronary Orbital Atherectomy System (OAS) as a treatment for severely calcified coronary arteries.

22 Oct 2013

Study: Bottle feeding appears to increase risk of HPS in infants

Bottle feeding appears to increase the risk infants will develop hypertrophic pyloric stenosis (HPS), a form of stomach obstruction, and that risk seems to be magnified when mothers are older and have had more than one child, according to a study published by JAMA Pediatrics, a JAMA Network publication.

22 Oct 2013

Binge drinking increases atherosclerotic progression, stroke mortality risk in men

A Finnish population-based study showed that binge drinking was associated with increased atherosclerotic progression in an 11-year follow-up of middle-aged men. The progression of atherosclerosis was increased among men who consumed 6 drinks or more on one occasion.

21 Oct 2013

DePuy Synthes Spine expands collaboration with Brainlab

DePuy Synthes Spine announced it is expanding its collaboration with Brainlab through the worldwide launch of navigation-ready instrumentation for its leading spine systems, and an exclusive global agreement to co-market Airo Mobile Intraoperative CT by Brainlab.

11 Oct 2013

Bluhm Institute enrolls first patient in SALUS trial to evaluate movable, non-metallic heart valve

Northwestern's Bluhm Cardiovascular Institute has enrolled its first participant in SALUS, a clinical trial studying the effectiveness of a prosthetic aortic heart valve that can be placed without open-heart surgery.

10 Oct 2013

New "mPACT" program for posterior mini open fixation and fusion procedures from DePuy Synthes Spine

DePuy Synthes Spine announced the global launch of "mPACT" (medialized Posterior Approach Cortical Trajectory), a program that combines implants, education, clinical research and procedural support for posterior mini open fixation and fusion procedures.

10 Oct 2013

Gas transfer excels in predicting mortality in COPD

Researchers say that measuring gas transfer is the most effective way to predict mortality in chronic obstructive pulmonary disease, after finding that it outperformed both spirometry and plethysmography for the purpose.

3 Oct 2013

Minimally invasive treatments for lumbar spinal stenosis: an interview with James Corbett, President & Chief Executive Officer of Vertos Medical

Lumbar spinal stenosis (LSS) is a degenerative, age-related narrowing of the lower spinal canal that causes pressure on the nerves, leading to pain and reduced mobility. Symptoms include pain, numbness, or tingling in the lower back, legs, or buttocks, which limits your ability to stand or walk.

30 Sep 2013

FDA approves revised labeling for Sapien Transcatheter Heart Valve

The U.S. Food and Drug Administration today approved revised labeling for the Sapien Transcatheter Heart Valve, making the device available to an expanded group of patients who have inoperable aortic valve stenosis, a disease of the heart valves that causes narrowing of the aortic valve, restricting blood flow from the heart.

24 Sep 2013

CRF to present groundbreaking clinical trial findings at TCT 2013 scientific symposium

The Cardiovascular Research Foundation (CRF) has announced the late breaking trials and first report investigations that will be presented at next month's Transcatheter Cardiovascular Therapeutics (TCT) 2013 scientific symposium.

21 Sep 2013

Swallow therapy combats post-radiotherapy dysphagia

Swallowing exercises can help to minimize the risk for dysphagia in patients undergoing radiotherapy for head and neck cancer, a case study suggests.

20 Sep 2013

Women with acute coronary syndrome less likely to have chest pain than men

A higher proportion of women than men 55 years and younger did not have chest pain in acute coronary syndromes (ACS, such as heart attacks or unstable angina), although chest pain was the most common symptom for both sexes, according to a study published by JAMA Internal Medicine, a JAMA Network publication.

17 Sep 2013

Boston Scientific announces positive results from REPRISE II clinical trial of Lotus Valve System

Boston Scientific Corporation reported favorable six-month results from the first 60 patients enrolled in the REPRISE II clinical trial evaluating the safety and performance of the Lotus™ Valve System in symptomatic patients with severe aortic stenosis considered at high risk for surgical valve replacement.

17 Sep 2013

Recanalization of extracranial internal carotid artery occlusion: A retrospective study

Carotid endarterectomy can benefit the majority of patients with severe carotid artery stenosis. However, the therapeutic effects of this technique in patients with symptomatic internal carotid artery occlusion remain controversial.

17 Sep 2013

Experimental agent fails to increase HDL levels, reveals new study

The search continues for an agent that increases high-density lipoprotein (HDL) and reduces arterial plaque, after the experimental apolipoprotein A1 (apoA1) inducer, RVX-208 failed to do so in the ApoA1 Synthesis Stimulation and Intravascular Ultrasound for Coronary Atheroma Regression Evaluation (ASSURE) study.

5 Sep 2013

Preventive PCI for patients with ST elevation myocardial infarction results in better outcomes

Heart attack patients with ST elevation who undergo a preventive procedure to unblock additional coronary arteries have significantly better outcomes than those whose treatment is confined to the culprit blockage only, according to the results of the Preventive Angioplasty in Myocardial Infarction (PRAMI) Trial

5 Sep 2013

Multiple risk factors eliminate impact of AF on stroke risk, but more research is needed

Dr Benn Christiansen said: "We know that atrial fibrillation increases the risk of ischemic stroke. And in patients with atrial fibrillation or previous ischemic stroke, the risk of stroke increases with the number of risk factors.

5 Sep 2013

Stenosis News and Research

Clinical trial finds COREVALVE reduces rate of death, stroke in patients with aortic stenosis

Early morning SBP signals silent brain stenosis

Stroke prevention study: Medication plus lifestyle changes safe, effective than surgical interventions

CSI receives PMA approval to market Diamondback 360 Coronary Orbital Atherectomy System

Study: Bottle feeding appears to increase risk of HPS in infants

Binge drinking increases atherosclerotic progression, stroke mortality risk in men

DePuy Synthes Spine expands collaboration with Brainlab

Bluhm Institute enrolls first patient in SALUS trial to evaluate movable, non-metallic heart valve

New "mPACT" program for posterior mini open fixation and fusion procedures from DePuy Synthes Spine

Gas transfer excels in predicting mortality in COPD

Minimally invasive treatments for lumbar spinal stenosis: an interview with James Corbett, President & Chief Executive Officer of Vertos Medical

FDA approves revised labeling for Sapien Transcatheter Heart Valve

CRF to present groundbreaking clinical trial findings at TCT 2013 scientific symposium

Swallow therapy combats post-radiotherapy dysphagia

Women with acute coronary syndrome less likely to have chest pain than men

Boston Scientific announces positive results from REPRISE II clinical trial of Lotus Valve System

Recanalization of extracranial internal carotid artery occlusion: A retrospective study

Experimental agent fails to increase HDL levels, reveals new study

Preventive PCI for patients with ST elevation myocardial infarction results in better outcomes

Multiple risk factors eliminate impact of AF on stroke risk, but more research is needed

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