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Pioneering gene therapy for rare immune disorder shows promise in early pre-clinical studies

The development of a pioneering gene therapy to treat a devastating, rare immune disorder led by UCL scientists is set to move into its next phase following promising early pre-clinical studies.

27 Jun 2026

Lighting the way towards a new treatment for blindness

Adelaide University researchers have carried out the first in-human trial of a new type of treatment for a leading cause of blindness in working age adults, with promising results.

27 Jun 2026

Artificial intelligence improves prediction of cancer drug resistance

A comprehensive review recently published in Current Molecular Pharmacology (2026, Volume 19, Pages 85–96) examines the rapidly evolving landscape of computational tools for predicting tumour drug resistance.

26 Jun 2026

Rare pelvic schwannoma removed with nerve-sparing laparoscopic surgery

Through interdepartmental collaboration, a young woman's quality of life and ability to walk were restored following the laparoscopic removal of a rare, benign tumor of neurological origin in the lesser pelvis, known as a schwannoma (also called a neurinoma).

26 Jun 2026

AI-guided microneedle patch changes shape to heal chronic wounds

Chronic wounds remain a major healthcare challenge, especially for people with diabetes, who often experience delayed healing, persistent inflammation, and a higher risk of infection.

26 Jun 2026

Single DNA injection provides long-lasting weight loss in mouse study

Scientists at The Wistar Institute have shown that a single injection of a small, circular piece of genetic instructions can produce weight loss and blood glucose control in murine models that lasts up to 10 times as long as incretin-mimicking drugs like Ozempic and Wegovy.

26 Jun 2026

Engineered CAR T cells successfully target bladder cancer in mice

Researchers at Weill Cornell Medicine, Cedars-Sinai Medical Center, and Roswell Park Comprehensive Cancer Center have developed genetically engineered CAR T cells that specifically target and kill bladder cancer cells.

26 Jun 2026

New rehabilitation platform combines virtual reality and nerve stimulation for stroke recovery

Researchers at the Medical University of Vienna and ETH Zurich have developed a rehabilitation platform for people suffering from the long-term effects of a stroke, which combines virtual reality with targeted sensory nerve stimulation.

26 Jun 2026

New project investigates gut microbiome for personalized bowel disease therapies

The gut microbiome plays an important role in inflammatory bowel disease. In the research project MikrobiomProCheck, researchers are investigating how microbiome data can in future be used for diagnostics, disease monitoring and personalized therapies.

26 Jun 2026

Doctors clarify differences between two steroid-induced facial skin conditions

Doctors have long confused two steroid-induced facial skin conditions, leading to wrong treatments and poor outcomes.

26 Jun 2026

Longer hormone exposure linked to healthier brain aging in women

Research indicates that hormonal therapies and later menopause are associated with increased brain volume and thickness, promoting healthier aging.

26 Jun 2026

Neuroticism and adversity dominate depression and anxiety risk in UK Biobank study

In a UK Biobank study of 87,648 adults followed for 13.7 years, psychosocial factors accounted for the largest estimated population burden of depression and anxiety in both women and men. Neuroticism symptoms, childhood and adult adversity, obesity, chronic inflammation, and some reproductive factors in women were linked to incident mental health outcomes, although the PAF estimates remain theoretical and not proof of causality.

25 Jun 2026

Gut microbes emerge as potential players in estrogen-driven cancers

A new review maps how the endocrine-microbiome axis expands the estrobolome concept, showing that gut microbes may alter estrogen recycling, produce hormone-like metabolites, and shape inflammation and tissue environments in hormone-driven cancers. Human evidence remains mostly associative, so the authors call for causal models, longitudinal multi-omics, multi-kingdom profiling, and sex-stratified studies before microbiome-guided cancer strategies enter routine care.

25 Jun 2026

Lipid nanoparticles enhance immune response against lung cancer

Researchers at the University of Arizona R. Ken Coit College of Pharmacy have developed a new strategy that helps the immune system recognize and attack lung cancer tumors more effectively.

25 Jun 2026

Researchers develop novel strategy to selectively target tumor microenvironments

A new collaborative study reports the discovery and application of a novel therapeutic strategy to selectively target EGFR and other kinases with controlled release in tumor microenvironments to improve therapeutic efficacy, with promising results.

25 Jun 2026

Musculoskeletal pain in children is often underestimated and misunderstood

Three out of every ten Brazilian children and adolescents complain of musculoskeletal pain (affecting bones, ligaments, and muscles).

25 Jun 2026

Peacemaker immune cells offer new hope for restoring immune tolerance

'Peacemaker' immune cells could help treat diseases ranging from type 1 diabetes to neurodegeneration by restoring immune tolerance, according to a new paper in Frontiers in Science.

25 Jun 2026

Transfemoral J-Valve device improves symptoms in severe aortic regurgitation patients

New research simultaneously published today in JSCAI and presented at New York Valves 2026 reported favorable one-year outcomes in patients with symptomatic severe aortic regurgitation following treatment with the investigational J-Valve Transfemoral System.

25 Jun 2026

Natural bioactive compounds target miR-29a molecule to prevent cancer development

A study published in Current Molecular Pharmacology provides a comprehensive analysis of microRNA-29a (miR-29a) as a pivotal regulator in cancer development, and examines how natural bioactive compounds may offer a promising strategy for cancer prevention by modulating its expression.

25 Jun 2026

AI-driven approach identifies promising new target for CAR T cell therapy

Leading CAR T cell therapy researchers have developed a human-in-the-loop artificial intelligence (AI) framework that firmly centers scientists' expertise to find viable target antigens for CAR T cell therapy.

25 Jun 2026

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Therapy News and Research

Pioneering gene therapy for rare immune disorder shows promise in early pre-clinical studies

Lighting the way towards a new treatment for blindness

Artificial intelligence improves prediction of cancer drug resistance

Rare pelvic schwannoma removed with nerve-sparing laparoscopic surgery

AI-guided microneedle patch changes shape to heal chronic wounds

Single DNA injection provides long-lasting weight loss in mouse study

Engineered CAR T cells successfully target bladder cancer in mice

New rehabilitation platform combines virtual reality and nerve stimulation for stroke recovery

New project investigates gut microbiome for personalized bowel disease therapies

Doctors clarify differences between two steroid-induced facial skin conditions

Longer hormone exposure linked to healthier brain aging in women

Neuroticism and adversity dominate depression and anxiety risk in UK Biobank study

Gut microbes emerge as potential players in estrogen-driven cancers

Lipid nanoparticles enhance immune response against lung cancer

Researchers develop novel strategy to selectively target tumor microenvironments

Musculoskeletal pain in children is often underestimated and misunderstood

Peacemaker immune cells offer new hope for restoring immune tolerance

Transfemoral J-Valve device improves symptoms in severe aortic regurgitation patients

Natural bioactive compounds target miR-29a molecule to prevent cancer development

AI-driven approach identifies promising new target for CAR T cell therapy

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