Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Gene therapy potential of the protein vasostatin for treatment of pancreatic cancer

A gene responsible for the production of a protein called vasostatin may prove a promising new way of treating pancreatic cancer, suggests research published ahead of print in Gut.

15 Nov 2005

Lack of aggressive treatment for clogged leg blood vessels means missed heart attack prevention opportunity

Despite the fact that clogged arteries in the legs usually mean clogged arteries near the heart, doctors often fail to give heart-protecting drugs to people with severe leg blood vessel blockages, a new University of Michigan-led study finds.

15 Nov 2005

Torcetrapib - Lipitor drug combo shows promise

According to drug company Pfizer the results of two mid-stage studies on its experimental cholesterol drug torcetrapib, combined with its cholesterol drug Lipitor, were so promising that the company will continue into the final stage.

15 Nov 2005

Vietnamese researchers say bird flu already resisant to Tamiflu

Scientists in Vietnam are concerned that the deadly bird flu may have infected two more people, and they suspect the virus may have mutated into a more dangerous form which could spread in mammals, and cause outbreaks in poultry.

15 Nov 2005

Better understanding of cancer cachexia

New research shows that a wasting condition responsible for nearly a third of all cancer deaths involves the loss of an essential muscle protein that is also lost in people with muscular dystrophy.

15 Nov 2005

Nerve-cell dendrites splice messenger RNA

Researchers at the University of Pennsylvania School of Medicine have discovered that nerve-cell dendrites have the capacity to splice messenger RNA (pre-mRNA), a process once believed to only take place in the nucleus of cells.

14 Nov 2005

Olfactory epithelium plays a critical role in pheromone detection

Howard Hughes Medical Institute researchers have discovered that pheromones essential for mating behavior in mice are recognized by the nose and not by the vomeronasal system, as researchers had long suspected.

14 Nov 2005

New respiratory synctial virus treatment for at-risk infants under study

A new, enhanced-potency onoclonal antibody designed to keep the sniffles from turning into a devasting illness in at-risk babies is under study at the Medical College of Georgia Children's Medical Center.

14 Nov 2005

Protein discovery may have implications for treating E. coli 0157:H7 infection

A discovery by Queen's researchers of a previously unknown protein may open the door to more effective treatment of a deadly strain of the E. coli bacteria.

14 Nov 2005

Why the bird flu virus H5N1 is so deadly to humans

A study published today in the open access journal Respiratory Research reveals that, in human cells, the virus can trigger levels of inflammatory proteins more than 10 times higher than the common human flu virus H1N1.

14 Nov 2005

Biomedical device allows stem cells derived from adult bone marrow to be grown in sufficient quantities to permit far more research

Human stem cells offer tremendous hope for the development of revolutionary medical treatments for these and a variety of other human health problems.

14 Nov 2005

Discovery of novel form of regulation of the GLI1 gene

The Quaking gene, first described as a mutation in mice that causes rapid tremor, is thought to suppress tumor formation and protect humans from cancer.

14 Nov 2005

Molecular origins of diabetes

An unexpected twist to a discovery reported just two months ago may significantly improve our understanding about the molecular origins of diabetes.

14 Nov 2005

First step in exploring the GnRH reproduction-related circuitry in the brain

Howard Hughes Medical Institute researchers have discovered a vast network of neurons in the brain of mice that governs reproduction and controls the effects of reproductive status on other brain functions.

14 Nov 2005

Researchers can now identify patients likely to respond to cancer drug therapy

Researchers at UCLA's Jonsson Cancer have identified key characteristics in certain deadly brain tumors that make them 51 times more likely to respond to a specific class of drugs than tumors in which the molecular signature is absent.

13 Nov 2005

University of Alberta researchers pioneer gene therapy to restore alveoli and lung capillaries in damaged rat lungs

The good news is that medical advances in perinatal care have allowed us to save many more premature babies. The bad news is they're often at risk of developing bronchopulmonary dysplasia--a chronic lung disease caused by having to place the tiny infants on ventilators and oxygen-rich therapy for acute respiratory failure.

13 Nov 2005

How protein-enriched meals decrease hunger and reduce eating

Researchers have uncovered new evidence to explain the observation that diets rich in protein stunt the appetite, according to a report in the November Cell Metabolism.

13 Nov 2005

Cellular signal may determine life or death for damaged brain cells

Scientists at the Universities of Heidelberg and Ulm and a unit of the European Molecular Biology Laboratory (EMBL) in Monterotondo, Italy, have discovered that a specific signal within brain cells may determine whether they live or die after a stroke.

13 Nov 2005

Promising functional readouts of immunity in a blood-stage malaria vaccine trial

A malaria vaccine remains the most desired tool to combat the worsening malaria epidemic in many developing countries. Pierre Druilhe and colleagues (from the Institut Pasteur in Paris) have completed the first human trial of a vaccine based on MSP3, a protein present on the surface of the malaria parasite, with very encouraging results.

13 Nov 2005

Scientists discover why lung, but not skin, anthrax infections are lethal

Scientists from the Max Planck Institute for Infection Biology in Berlin discovered why lung, but not skin, anthrax infections are lethal. As reported in the newest issue of PloS Pathogen (November 2005) Neutrophils, a form of white blood cells, play a key role in anthrax infections.

13 Nov 2005