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Detection of immune and clotting dysfunction in plasma and saliva after SARS-CoV-2 infection

It is becoming increasingly clear that individuals recovering from acute coronavirus disease (COVID-19) may develop post-acute sequelae (Post-Acute Coronavirus Syndrome, PACS).

23 Mar 2022

Study reveals differences in SARS-CoV-2 and SARS-CoV-1 spike protein conformational changes

Researchers determine the differential dynamic behavior of SARS-CoV-1 and SARS-CoV-2 spike proteins.

22 Mar 2022

Powerful tool to monitor membrane proteins trafficking for drug discovery

Inside your body on the surface of cell membranes, a metaphorical communication and traffic network is underway as hormones - or chemical messengers - bind to cell membrane receptors to fine tune how the cell behaves.

22 Mar 2022

CD63-expressing extracellular vesicles neutralize SARS-CoV-2 variants of concern

Researchers evaluate antiviral effects of CD63 tetraspanin extracellular vesicles against SARS-CoV-2 and HIV-1.

22 Mar 2022

Rubella antibodies vs. COVID-19

A new study describes a potential relationship between antibody titers against the rubella virus and the severity of COVID-19.

22 Mar 2022

Vaccine-induced antibody response to SARS-CoV-2 Omicron variant in patients with B cell malignancies with and without active B cell-targeted therapy

Researchers have determined the effect of booster immunization on the levels of antibodies generated, against SARS-CoV-2 variants, including the Omicron strain, in cancer patients with or without active B cell-targeted therapy.

22 Mar 2022

Researchers identify a protein that protects against breast cancer growth

Researchers at Karolinska Institutet in Sweden have identified a protein that protects against breast tumor growth and that can be linked to a better prognosis in breast cancer patients.

22 Mar 2022

Maternal and infant antibody levels and transplacental transfer following SARS-CoV-2 infection and vaccination

A recent study evaluated maternal antibody responses against SARS-CoV-2 and transplacental transfer.

22 Mar 2022

SARS-CoV-2 nanobody that binds to the receptor-binding domain could prevent COVID-19 in animals

A new study assessed the potential of a nanobody – directly prepared by binding to SARS-CoV-2 spike receptor-binding domain protein, in the treatment of COVID-19.

22 Mar 2022

Molecular dynamic simulations unveil conformational dynamics of SARS-CoV-2 spike protein RBD and ACE2 receptor

Researchers presented a systematic analysis of the affinity and conformational dynamics between the binding of SARS-CoV-2 receptor-binding domain spike protein and the host angiotensin-converting enzyme 2 receptor.

22 Mar 2022

The effect of SARS-CoV-2 on the expression of CD48 in the lungs and in the peripheral blood of COVID-19 patients

Researchers performed an in situ analysis to evaluate the correlation between CD48 expression and COVID-19.

22 Mar 2022

Waning antibody responses in SARS-CoV-2-infected or vaccinated population

A recent study posted to the bioRxiv* preprint server evaluated the effects of the waning of antibodies after coronavirus disease 2019 (COVID-19) infection or vaccination.

22 Mar 2022

Research characterizes efficacy of various COVID vaccines against Omicron BA.1 and BA.2

A recent study posted to the bioRxiv* preprint server demonstrated the neutralizing capacity of existing SARS-CoV-2 vaccines against the severe acute respiratory coronavirus 2 (SARS-CoV-2) Omicron BA.2 and BA.1 sublineages.

22 Mar 2022

SARS-CoV-2 infection risk among dialysis patients during Omicron surge

A recent study posted to the medRxiv* preprint server evaluated the antibody responses against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) patients receiving hemodialysis.

22 Mar 2022

Association between seropositivity and comorbidities after COVID-19 vaccination

In a recent study posted to the medRxiv* preprint server, researchers demonstrated that comorbidities attenuated the chance of seropositivity following coronavirus disease 2019 (COVID-19) vaccination.

22 Mar 2022

Is COVID-19 on the verge of ending?

Researchers explore the changes arising in SARS-CoV-2 over time.

21 Mar 2022

A circRNA COVID vaccine with potential to neutralize SARS-CoV-2 variants

Researchers demonstrate the broad neutralization potential of a strategically engineered circRNA using mice as a model system.

21 Mar 2022

Researchers win NIH grant to treat human brain cancer with a drug previously used on canines

The National Institutes of Health is awarding a $3.8 million grant to John Rossmeisl, the Dr. and Mrs. Dorsey Taylor Mahin Professor of Neurology and Neurosurgery at the Virginia-Maryland College of Veterinary Medicine, and Waldemar Debinski, cancer biology professor at the Wake Forest School of Medicine.

21 Mar 2022

Trial reveals effectiveness of axi-cel as first-line treatment for high-risk lymphoma

Results from the ZUMA-12 trial led by researchers at The University of Texas MD Anderson Cancer Center showed that first-line treatment with axicabtagene ciloleucel (axi-cel), a chimeric antigen receptor (CAR) T cell therapy, achieved a high rate of complete response in patients with high-risk large B-cell lymphoma (LBCL).

21 Mar 2022

Oral drug that reverses immune aging effectively prevents death in COVID-19 mouse model

The immune system deteriorates with age, making COVID-19 particularly deadly in older people - but to date, no clinically available medication addresses this key risk factor.

21 Mar 2022

Receptor News and Research

Detection of immune and clotting dysfunction in plasma and saliva after SARS-CoV-2 infection

Study reveals differences in SARS-CoV-2 and SARS-CoV-1 spike protein conformational changes

Powerful tool to monitor membrane proteins trafficking for drug discovery

CD63-expressing extracellular vesicles neutralize SARS-CoV-2 variants of concern

Rubella antibodies vs. COVID-19

Vaccine-induced antibody response to SARS-CoV-2 Omicron variant in patients with B cell malignancies with and without active B cell-targeted therapy

Researchers identify a protein that protects against breast cancer growth

Maternal and infant antibody levels and transplacental transfer following SARS-CoV-2 infection and vaccination

SARS-CoV-2 nanobody that binds to the receptor-binding domain could prevent COVID-19 in animals

Molecular dynamic simulations unveil conformational dynamics of SARS-CoV-2 spike protein RBD and ACE2 receptor

The effect of SARS-CoV-2 on the expression of CD48 in the lungs and in the peripheral blood of COVID-19 patients

Waning antibody responses in SARS-CoV-2-infected or vaccinated population

Research characterizes efficacy of various COVID vaccines against Omicron BA.1 and BA.2

SARS-CoV-2 infection risk among dialysis patients during Omicron surge

Association between seropositivity and comorbidities after COVID-19 vaccination

Is COVID-19 on the verge of ending?

A circRNA COVID vaccine with potential to neutralize SARS-CoV-2 variants

Researchers win NIH grant to treat human brain cancer with a drug previously used on canines

Trial reveals effectiveness of axi-cel as first-line treatment for high-risk lymphoma

Oral drug that reverses immune aging effectively prevents death in COVID-19 mouse model

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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