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Understanding the impact of tobacco smoking and smoking cessation on life expectancy of HIV patients in South Africa

Krishna Reddy, MD, MS, a physician-investigator at the Medical Practice Evaluation Center and the Tobacco Research and Treatment Center at Massachusetts General Hospital and an Associate Professor of Medicine at Harvard Medical School, is the senior author of a recently published paper in Journal of the International AIDS Society: Tobacco Smoking, Smoking Cessation and Life Expectancy Among People with HIV on Antiretroviral Therapy in South Africa: A Simulation Modelling Study.

16 Jul 2024

Navigating adjuvant therapy options in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the most prevalent malignancies globally and is the third leading cause of cancer-related deaths.

16 Jul 2024

New approaches for repairing the function of mutated proteins that cause stroke

Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL) is a rare, severe, and deadly genetic disorder characterized by damage to small blood vessels in the brain and which triggers strokes.

16 Jul 2024

Cellular Origins appoints Geoffrey Hodge as Non-Executive Director

Appointment brings additional significant strategic, technical and commercial experience to the Board.

From Cellular Origins 16 Jul 2024

Study shows oral semaglutide matches DPP-4i in adherence and persistence for type 2 diabetes

Researchers found that adherence and persistence in T2D patients using oral semaglutide is similar to DPP-4i, but semaglutide users required fewer concurrent medications, indicating higher long-term efficacy.

16 Jul 2024

Discovery of "unconventional" immune response opens new avenue in TB vaccine development

An "unconventional" immune response now identified by scientists from the Hackensack Meridian Center for Discovery and Innovation (CDI) is a potential new pathway for developing new vaccines for tuberculosis (TB), according to a new publication.

15 Jul 2024

Researchers discover key functions of IRF1 in cancer progression and treatment response

Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have uncovered new details about the role of a protein called interferon regulatory factor (IRF1) in cancer progression and treatment response, offering new insight that can potentially help improve the effectiveness of cancer immunotherapy.

15 Jul 2024

Children in deprived areas face higher risk of severe tooth decay requiring hospital extraction

Researchers at Queen Mary University of London have found that children living in areas with high levels of deprivation are three times more likely to have severe tooth decay that requires a dental extraction in hospital, compared with children living in more affluent areas.

15 Jul 2024

Triad of immune cells key to successful cancer immunotherapy, study finds

There's a frustrating fact about today's immunotherapies for cancer. While sometimes they work beautifully - completely eliminating or greatly reducing cancer in particular patients - other times they don't work at all. It's a mystery.

15 Jul 2024

Immunotherapy response assessment in malignant pleural mesothelioma: FDG-PET/CT vs. CT

A new research paper was published in Oncotarget's Volume 15 on June 20, 2024, entitled, "Comparison of FDG-PET/CT and CT for evaluation of tumor response to nivolumab plus ipilimumab combination therapy and prognosis prediction in patients with unresectable malignant pleural mesothelioma."

15 Jul 2024

Study reveals altered neural signature in patients with depression

As parents, teachers and pet owners can attest, rewards play a huge role in shaping behaviors in humans and animals.

15 Jul 2024

ARPA-H funding boosts Wyss Institute's RNA therapeutic project

With the award for up to $27 million from the Advanced Research Projects Agency for Health (ARPA-H), a collaborative research project at the Wyss Institute for Biologically Inspired Engineering at Harvard University will advance a disease-agnostic novel RNA therapeutic with the potential to treat diverse diseases, and to be effectively and rapidly deployable.

15 Jul 2024

Innovative approaches in polymer nanoparticle synthesis for RNA therapeutics

RNA therapy with polymer nanoparticles is considered a promising approach for the treatment of various illnesses.

15 Jul 2024

Long-term, 30-year CVD risk may help inform therapy for stage 1 hypertension

A comparison of two risk prediction tools used to calculate an individual's risk of developing cardiovascular disease (CVD) suggests that the long-term, 30-year risk should be considered in addition to the short-term, 10-year risk to help inform when to begin medication therapy for stage 1 hypertension, or high blood pressure, according to new research published today in Hypertension, an American Heart Association journal.

15 Jul 2024

Survey: Most Americans believe it's normal for women to experience pain and incontinence post-childbirth

A new national survey by the Orlando Health Advanced Rehabilitation Institute finds most Americans believe it's normal for women to experience pain, pressure and incontinence after having children.

15 Jul 2024

Mogrify appoints Dr. Jonathan Appleby as Chief Scientific Officer

Strategic hire bolsters executive leadership team as Company progresses multiple therapeutic programs toward and into clinical development.

From Mogrify 15 Jul 2024

Review highlights unique characteristics and mechanisms of ferroptosis

Junxia Min, Fudi Wang, et al., at Zhejiang University School of Medicine, China, provided an in-depth review on the programmed cell death known as ferroptosis, which is driven by iron-dependent lipid peroxidation.

14 Jul 2024

Poll: Majority of Brits fear cancer diagnosis more than any other condition

Two-thirds of the public say they are very or somewhat worried about being told they have the disease – higher than for any other medical condition, including dementia and having a heart attack – according to polling released today.

14 Jul 2024

Do probiotics really benefit healthy people?

Recent research in Advances In Nutrition reviews the benefits of probiotics for healthy individuals, highlighting evidence gaps and the need for further study to support preventive recommendations.

14 Jul 2024

Common therapies contain different cell types, study finds

Researchers from University of California San Diego have found that two of the most frequently administered stem cell therapies, which are often used interchangeably, actually contain completely different types of cells. The results challenge the current "one-cell-cures-all" paradigm in orthopedic stem cell therapeutics and highlight the need for more informed and rigorous characterization of injectable stem cell therapies before they are marketed for use in patients.

13 Jul 2024

Therapy News and Research

Understanding the impact of tobacco smoking and smoking cessation on life expectancy of HIV patients in South Africa

Navigating adjuvant therapy options in hepatocellular carcinoma

New approaches for repairing the function of mutated proteins that cause stroke

Cellular Origins appoints Geoffrey Hodge as Non-Executive Director

Study shows oral semaglutide matches DPP-4i in adherence and persistence for type 2 diabetes

Discovery of "unconventional" immune response opens new avenue in TB vaccine development

Researchers discover key functions of IRF1 in cancer progression and treatment response

Children in deprived areas face higher risk of severe tooth decay requiring hospital extraction

Triad of immune cells key to successful cancer immunotherapy, study finds

Immunotherapy response assessment in malignant pleural mesothelioma: FDG-PET/CT vs. CT

Study reveals altered neural signature in patients with depression

ARPA-H funding boosts Wyss Institute's RNA therapeutic project

Innovative approaches in polymer nanoparticle synthesis for RNA therapeutics

Long-term, 30-year CVD risk may help inform therapy for stage 1 hypertension

Survey: Most Americans believe it's normal for women to experience pain and incontinence post-childbirth

Mogrify appoints Dr. Jonathan Appleby as Chief Scientific Officer

Review highlights unique characteristics and mechanisms of ferroptosis

Poll: Majority of Brits fear cancer diagnosis more than any other condition

Do probiotics really benefit healthy people?

Common therapies contain different cell types, study finds

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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