Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Researchers uncover how the inhaled form of anthrax disarms bacteria-fighting white blood cells before they can fend off the disease

The lethal toxin in anthrax paralyzes neutrophils, the white blood cells that act as the body's first defense against infection, by impairing how they build tiny filaments that allow them to crawl throughout the body and eat invading bacteria.

6 Sep 2005

Diet rich in soy protein may alleviate fatty liver

A group of researchers from Mexico has discovered that a diet rich in soy protein may alleviate fatty liver, a disease which often accompanies diabetes. The details of their findings appear in the September issue of the Journal of Lipid Research, an American Society for Biochemistry and Molecular Biology journal.

6 Sep 2005

Osteopontin protein found to be more common in patients with lung fibrosis

Idiopathic pulmonary fibrosis (IPF) is a scarring disease without a cure, irreparably damaging the ability of the tissue to transfer oxygen into the bloodstream.

6 Sep 2005

Strong social gradient in the metabolic syndrome

It is well documented that individuals with higher social status have lower risk of coronary heart disease (CHD). This is generally not explained by differences in lifestyle factors such as smoking and lack of exercise.

6 Sep 2005

Phase II clinical study of ularitide

The European Society of Cardiology (ESC) today highlighted results of a Phase II clinical study of ularitide, a synthetic form of a natriuretic peptide synthesized in the kidney for patients with acute decompensated congestive heart failure (ADHF).

5 Sep 2005

New vaccine with the potential to protect against fungal pathogens

A group of scientists in Italy have developed a vaccine with the potential to protect against fungal pathogens that commonly infect humans, according to a study by Torosantucci and colleagues in the September 5 issue of The Journal of Experimental Medicine.

5 Sep 2005

Genome of mammals is much more complex than previously thought

More than 100 scientists from Australia, Asia, Europe and the US have been probing the genome of the mouse in a joint study lasting several years.

5 Sep 2005

New findings suggest balancing Chk1 activity will produce less toxic cancer drugs

A study published by The Burnham Institute in the September edition of Molecular Cell reports that a cell-cycle checkpoint protein, known to be activated by an important class of anticancer drugs, may play crucial roles in both the hampering of therapeutic actions and aiding cancer cells to "recover" and start dividing again after treatment with these drugs.

5 Sep 2005

New understanding of how our genome works to produce a complex organism like a human being

A series of discoveries by an international consortium of scientists, including a team from The University of Queensland's Institute for Molecular Bioscience (IMB), will transform our understanding of how our genome works to produce a complex organism like a human being.

4 Sep 2005

Rett Syndrome gene discovery

Adrian Bird of the University of Edinburgh and colleagues report in the online issue of Molecular Cell that the "Rett Syndrome protein", MeCP2, only binds to genes with a specific sequence of nucleotide bases. This knowledge will aid in the identification of the genes that are regulated by the gene MECP2

4 Sep 2005

Molecular switch that turns on the production of myelin

Scientists at New York University School of Medicine report in a new study that they have identified the molecular switch that turns on the production of myelin, the fatty insulation around nerve cells that ensures swift and efficient communication in the nervous system.

1 Sep 2005

Potential new way to fight HIV

Researchers have confirmed for the first time the benefit of an innate defense system present in the few patients who remain healthy after years of infection with HIV despite receiving no treatment, according to an article published in the September edition of the Journal of Virology.

1 Sep 2005

One protein hardens enamel while the other weakens it, say USC researchers

A gene critical to tooth formation expresses a protein that is then cleaved into two proteins with seemingly opposite functions, according to a University of Southern California (USC)-led team of dental researchers.

1 Sep 2005

Study points to link to neurodegenerative disease target

A University of California - San Francisco (UCSF) study has found that a specific signaling link between neurons and muscles in the fruit fly is essential for keeping the insect's nervous system stable.

1 Sep 2005

Can a new combination treatment prevent a secondary stroke in children with sickle cell anemia?

St. Jude Children’s Research Hospital will lead a national Phase III clinical trial to investigate whether a new combination treatment can prevent a secondary stroke in children with sickle cell anemia (SCA) and eliminate the need for nightly injections with a drug that reduces iron overload in these patients.

1 Sep 2005

Scientists demonstrate power of new generalized screen to find function of noncoding RNAs

A team of investigators at The Scripps Research Institute and the Genomics Institute of the Novartis Research Foundation (GNF) have discovered a way to screen hundreds and potentially thousands of "noncoding" RNA molecules to discover their functions within cells.

1 Sep 2005

C. elegans worm provides clues to dealing with human disease

A step towards understanding cell mutations that cause a variety of human diseases, particularly in children -- including that which brings about premature aging and early death -- has been taken by researchers at the Hebrew University of Jerusalem Silberman Institute of Life Sciences and the John Hopkins University School of Medicine.

1 Sep 2005

Rev/Dex combo looks like a breakthrough treatment for multiple myeloma

Mayo Clinic Cancer Center investigators report that combination therapy with lenalidomide (Revlimid) and dexamethasone (combination is called Rev/Dex) looks like a breakthrough treatment for multiple myeloma. Results of a Phase II clinical trial were published online Aug. 23 in Blood.

1 Sep 2005

Two proteins for the diagnosis of lung diseases

Lung function pathology takes in some 200 diseases which have much radiological and pathological data in common, and which can greatly shorten the life of the patient, the last resort being a lung transplant.

1 Sep 2005

Prostate cancer manipulates an important group of signaling proteins called Wnts to establish itself in bone

Prostate cancer is a cruel disease. Left untreated, prostate cancer cells often metastasize, or spread, to bone where they form fracture-prone tumors that are extremely painful.

1 Sep 2005