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Eat your greens for healthy sperm genes

Men who consume a high amount of certain nutrients may produce healthier sperm than men who do not, an effect that appears to be more pronounced in older men, report US researchers.

3 Sep 2012

Closing in on neurologic biomarker diagnosis

A panel of five cerebrospinal fluid biomarkers may help doctors to accurately diagnose patients with various forms of dementia and parkinsonian disorders, research published in the Archives of Neurology suggests.

30 Aug 2012

FISH assay identifies only few lung cancer patients who could benefit from crizotinib

Break apart a couple worm-like chromosomes and they may reconnect with mismatched tips and tails - such is the case of the EML4-ALK fusion gene that creates 2-7 percent of lung cancers. Almost exactly a year ago, the FDA approved the drug crizotinib to treat these ALK+ lung cancer patients, who were likely never smokers. Informed doctors use the test called a FISH assay to check for the EML4-ALK fusion gene, and then if the test is positive, ALK+ patients benefit greatly from crizotinib.

29 Aug 2012

NYU-Poly creates ultra-sensitive biosensor to identify small single virus particles

Researchers at Polytechnic Institute of New York University (NYU-Poly) have created an ultra-sensitive biosensor capable of identifying the smallest single virus particles in solution, an advance that may revolutionize early disease detection in a point-of-care setting and shrink test result wait times from weeks to minutes.

29 Aug 2012

Abbott receives CE Marking for ARCHITECT testosterone assay

Abbott announced today CE Marking (Conformite Europeenne) for a testosterone assay with improved sensitivity and clinical utility.

28 Aug 2012

Parental methylated histones not transferred to daughter DNA

It's widely accepted that molecular mechanisms mediating epigenetics include DNA methylation and histone modifications, but a team from Thomas Jefferson University has evidence to the contrary regarding the role of histone modifications.

24 Aug 2012

NIH awards $100,000 STTR Phase I Grant to Transgenomic for pancreatic cancer research

Transgenomic, Inc. today announced it has been awarded a $100,000 Small Business Technology Transfer Program (STTR) Phase I Grant by the National Institutes of Health's National Center For Advancing Translational Sciences.

23 Aug 2012

Highly sensitive troponin assay shortens heart attack diagnosis

An algorithm that incorporates high-sensitivity cardiac troponin could allow accurate rule-in and rule-out of patients with acute chest pain within 1 hour of presentation, a study shows.

21 Aug 2012

New tool reveals surprising clues about how cancer cells respond to therapy

A new tool to observe cell behavior has revealed surprising clues about how cancer cells respond to therapy, and may offer a way to further refine personalized cancer treatments.

21 Aug 2012

MitoTarget Project and neurodegenerative diseases: an interview with Rebecca Pruss, Ph.D., CSO of Trophos

The MitoTarget Project was a project funded by the European Commission, under their FP7 programme. It was funding for a call published in 2007.

21 Aug 2012

Radiosensitivity molecular signature can lead to better radiation therapy decisions for breast cancer

Researchers at Moffitt Cancer Center, working with colleagues in Sweden, the Netherlands and Puerto Rico, have validated a radiosensitivity molecular signature that can lead to better radiation therapy decisions for treating patients with breast cancer.

16 Aug 2012

New tool reveals surprising clues about how cancer cells respond to therapy

A new tool to observe cell behavior has revealed surprising clues about how cancer cells respond to therapy - and may offer a way to further refine personalized cancer treatments.

15 Aug 2012

Endocrine Society revises clinical practice guideline for management of thyroid dysfunction

The Endocrine Society has made revisions to its 2007 Clinical Practice Guideline (CPG) for management of thyroid disease during pregnancy and postpartum. The CPG provides recommendations for diagnosis and treatment of patients with thyroid-related medical issues just before and during pregnancy and in the postpartum interval.

12 Aug 2012

University of Nevada researcher to optimize new rapid test for melioidosis

A new rapid test to diagnose melioidosis, a difficult infection to treat - and classified as a biothreat by the Centers for Disease Control and Prevention - is being optimized and tested by University of Nevada School of Medicine researcher David AuCoin.

9 Aug 2012

Lung cancer patients can be screened for ALK-inhibitor suitability

Anaplastic lymphoma kinase gene status in patients with lung adenocarcinoma can be determined non-invasively using circulating tumor cells, research shows.

8 Aug 2012

Applied BioCode receives U.S. patent for ‘Light Transmitted Assay Beads’

Applied BioCode, Inc. today announced that the United Stated Patent and Trademark Office has granted US Patent #8,232,092 "Light Transmitted Assay Beads," describing the method of decoding barcodes and analyzing bioassays using Barcoded Magnetic Beads (BMB) multiplex products.

7 Aug 2012

NeoGenomics introduces new molecular assay that detects SF3B1 gene mutations

NeoGenomics, Inc., a leading provider of cancer-focused genetic testing services, announced today that it has validated and launched the first molecular assay for clinical use in the United States that detects mutations in the SF3B1 gene (splicing factor 3b, subunit 1).

6 Aug 2012

Common ragweed may induce airways irritation through terpenoids

Allergy to pollen of common ragweed is increasingly affecting patients and is second only to grass pollen in terms of incidence in the general population of many European countries.

6 Aug 2012

Public Health Wales uses Luminex's xTAG GPP for outbreak investigations during Olympic events

Luminex Corporation announced today that Public Health Wales is using Luminex's CE marked xTAG Gastrointestinal Pathogen Panel (GPP) for outbreak investigation activities during Olympic and Paralympic training and events taking place in Wales. Results of a substantial diagnostic validation of the GPP test conducted by The Public Health Wales Microbiology laboratory team at the University Hospital of Wales, Cardiff, are anticipated to be published in a peer reviewed journal

From Luminex 6 Aug 2012

Anacardic acid can rescue some ALS phenotypes in vitro

A research group at the Center for iPS Cell Research and Application (CiRA) at Japan's Kyoto University has successfully recapitulated amyotrophic lateral sclerosis (ALS)-associated abnormalities in motor neurons differentiated from induced pluripotent stem cells (iPSCs) obtained from patients with familial ALS, a late-onset, fatal disorder which is also known for Lou Gehrig's disease. In a drug screening assay using the disease model, the team further found that the chemical compound anacardic acid can rescue some ALS phenotypes in vitro.

3 Aug 2012

Assay News and Research

Eat your greens for healthy sperm genes

Closing in on neurologic biomarker diagnosis

FISH assay identifies only few lung cancer patients who could benefit from crizotinib

NYU-Poly creates ultra-sensitive biosensor to identify small single virus particles

Abbott receives CE Marking for ARCHITECT testosterone assay

Parental methylated histones not transferred to daughter DNA

NIH awards $100,000 STTR Phase I Grant to Transgenomic for pancreatic cancer research

Highly sensitive troponin assay shortens heart attack diagnosis

New tool reveals surprising clues about how cancer cells respond to therapy

MitoTarget Project and neurodegenerative diseases: an interview with Rebecca Pruss, Ph.D., CSO of Trophos

Radiosensitivity molecular signature can lead to better radiation therapy decisions for breast cancer

New tool reveals surprising clues about how cancer cells respond to therapy

Endocrine Society revises clinical practice guideline for management of thyroid dysfunction

University of Nevada researcher to optimize new rapid test for melioidosis

Lung cancer patients can be screened for ALK-inhibitor suitability

Applied BioCode receives U.S. patent for ‘Light Transmitted Assay Beads’

NeoGenomics introduces new molecular assay that detects SF3B1 gene mutations

Common ragweed may induce airways irritation through terpenoids

Public Health Wales uses Luminex's xTAG GPP for outbreak investigations during Olympic events

Anacardic acid can rescue some ALS phenotypes in vitro

eBook: Using iPSCs models for human disease research and drug discovery eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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