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GARDP and Penta join forces to deal with drug-resistant infections in children

The Global Antibiotic Research & Development Partnership and Penta, the pediatric infectious diseases research network, have joined forces to tackle drug-resistant infections in children.

5 Mar 2019

Study identifies a close relative of diphtheria causing bacterium in hedgehogs

As cultural successors, hedgehogs reside in close proximity to humans. Close contacts, however, are not only beneficial but also bear risks for animals and humans. Road traffic, lawn mowers and infectious agents threaten the prickly insect eaters.

4 Mar 2019

Scientists create novel tool to advance search for antibacterial drugs

Indiana University researchers are advancing knowledge about how bacteria build their cell walls that could contribute to the search for new antibacterial drugs. They have created a new tool to observe living cells in real time under a microscope.

4 Mar 2019

CHOP researchers use machine-learning models for early detection of sepsis in NICU infants

Automated programs can identify which sick infants in a neonatal intensive care unit (NICU) have sepsis hours before clinicians recognize the life-threatening condition.

1 Mar 2019

Researchers reveal promising biomarker for vascular disease relapse

Researchers at Okayama University report in the journal Arthritis & Rheumatology that monitoring a particular antigen can be used for predicting relapse of the vascular disease AAV.

28 Feb 2019

Scientists use CRISPR to reveal the secret life of antimicrobial peptides

When it comes to the immune system, we usually think about lymphocytes like B and T cells or macrophages going on constant seek-and-destroy missions against invading pathogens like bacteria and viruses.

26 Feb 2019

Researchers engineer 'antibody-like' T cell receptors to combat deadly virus

Researchers have engineered "antibody-like" T cell receptors that can specifically stick to cells infected with cytomegalovirus, or CMV, a virus that causes lifelong infection in more than half of all adults by age 40.

23 Feb 2019

A simple change can drastically reduce unnecessary tests for urinary tract infections

Tests to detect urinary tract infections (UTI) often are performed routinely in hospitals, even when patients don't have symptoms.

22 Feb 2019

ICHE’s reviews on surgical infections, unnecessary urine tests, and nurses' role in antibiotic stewardship

Changes to standard urine orders in a computer physician order entry (CPOE) system, resulted in a 45% reduction in unnecessary urine cultures ordered, a change that is expected prevent unnecessary treatment of asymptomatic patients whose bacteria counts are above normal.

22 Feb 2019

Researchers uncover interspecies communication between gut bacteria and host

Bacteria in the gut do far more than help digest food in the stomachs of their hosts, they can also tell the genes in their mammalian hosts what to do.

22 Feb 2019

Reduced antibody adaptability may make the elderly more vulnerable to influenza

The influenza vaccine may be less effective in the elderly because their B cells are less capable of producing antibodies that can adapt to protect against new viral strains, researchers report February 19 in the journal Cell Host & Microbe.

21 Feb 2019

Thousands with chronic UTIs are not receiving the treatment they need

Many women may not be receiving the treatment they need because the gold-standard tests for UTIs fail to detect a significant proportion of bacteria.

21 Feb 2019

New sepsis test could save thousands of lives

Researchers have used a biosensor that can quickly identify biomarkers of sepsis and has the potential to save thousands of lives.

21 Feb 2019

Cervical microbiome may influence HPV infection more than previously thought

Infections with a Human Papillomavirus cause 99 percent of cervical cancer cases, and the disease's first sign is often the appearance of precancerous lesions on a woman's cervix. But bacteria may play an important role, too.

19 Feb 2019

Antimicrobial reusable coffee cups are less likely to become contaminated with bacteria, study shows

Antimicrobial reusable coffee cups are safer to use than ordinary plastic reusable cups, according to independent research undertaken by microbiologists at Aston University in Birmingham.

19 Feb 2019

Researchers identify suicide toxin in the bacteria responsible for tuberculosis

The bacteria responsible for tuberculosis can be killed by a toxin they produce unless it is neutralized by an antidote protein. The European team of scientists behind this discovery is coordinated by researchers from the Institute of Pharmacology and Structural Biology and the European Molecular Biology Laboratory.

18 Feb 2019

New protocol can help identify febrile infants at low risk for serious bacterial infections

A national research team led by UC Davis Health clinicians and researchers from the University of Michigan, Nationwide Children's Hospital and Columbia University, has derived and validated a new protocol for emergency departments that can determine which infant patients with fevers, age 60 days or younger, are at low risk of significant bacterial infections.

18 Feb 2019

Single CRISPR treatment can safely and stably correct genetic disease

Researchers at Duke University have shown that a single systemic treatment using CRISPR genome editing technology can safely and stably correct a genetic disease -- Duchenne muscular dystrophy (DMD) -- for more than a year in mice, despite observed immune responses and alternative gene editing outcomes.

18 Feb 2019

New protocol could help physicians to rule out bacterial infections in infants

A new protocol could help emergency room physicians to rule out life-threatening bacterial infections among infants up to 2 months of age who have fevers, potentially eliminating the need for spinal taps, unnecessary antibiotic treatments or expensive hospital stays.

18 Feb 2019

Scientists discover trigger that turns strep infections into devastating disease

Houston Methodist infectious disease scientists have discovered a previously unknown trigger that turns a relatively run-of-the-mill infection into a devastatingly ravenous, flesh-eating disease.

18 Feb 2019