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Researchers find conceivable alternative way to treat Pompe disease

Researchers at Duke Health have identified a potential new avenue for treating Pompe disease, a rare condition caused by the build-up of glycogen, a storage form of sugar, in cardiac and skeletal muscle, the liver and other tissues, due to deficiency of a particular enzyme.

25 Jul 2016

Scientists create new cell-membrane-like material with potential for water purification and drug delivery

Materials scientists have created a new material that performs like a cell membrane found in nature. Such a material has long been sought for applications as varied as water purification and drug delivery.

20 Jul 2016

Scientists find new way to clear urinary tract infections

The process cells use to secrete chemicals also appears to be the way to clear urinary tract infections, or UTIs, according to a study by researchers from Duke Health and Duke-National University of Singapore Medical School.

20 Jul 2016

Researchers discover novel neuroprotection strategies to slow progression of Parkinson's disease

Using a robust model for Parkinson's disease, University of Alabama at Birmingham researchers and colleagues have discovered an interaction in neurons that contributes to Parkinson's disease, and they have shown that drugs now under development may block the process.

20 Jul 2016

Study pinpoints how immune abnormalities in retina may lead to macular degeneration

In a study published this week in the Proceedings of the National Academy of Sciences, a University of Wisconsin-Madison research team pinpoints how immune abnormalities beneath the retina result in macular degeneration, a common condition that often causes blindness.

19 Jul 2016

Bad diet can affect immune system prior to weight gain, new research shows

Australian researchers have discovered that a bad diet has consequences on your immune system even before you notice an increase in body weight.

19 Jul 2016

Researchers discover how Zika virus travels from pregnant mother to fetus

Zika virus can infect numerous cell types in the human placenta and amniotic sac, according to researchers at UC San Francisco and UC Berkeley who show in a new paper how the virus travels from a pregnant woman to her fetus. They also identify a drug that may be able to block it.

19 Jul 2016

Scientists capture atomic level snapshots of how key enzyme modifies signaling proteins

Scientists have captured atomic level snapshots showing how one key enzyme modifies a protein involved in turning genes on or off inside cells. Understanding this process-which is particularly important when cells are first taking on specialized identities such as nerve cells, muscle, skin, and so on-helps explain how complex organisms can arise from a finite number of genes.

19 Jul 2016

Scientists capture new images of calcium-shuttling molecule linked to aggressive cancers

Scientists have captured new images of a calcium-shuttling molecule that has been linked to aggressive cancers. The three-dimensional structure could help researchers develop novel therapies and diagnostic tools for diseases that are caused by a malfunction in calcium adsorption.

18 Jul 2016

New, minimally invasive procedure may be effective for patients with FED

A new, minimally invasive procedure appears to be effective for many patients with Fuchs endothelial dystrophy (FED), a common eye disease, without the potential side effects and cost of the current standard of care, a cornea transplant.

13 Jul 2016

Researchers identify new mechanism by which bacteria outsmarts immune system

Bacteria are rapidly developing resistance mechanisms to combat even the most effective antibiotics.

13 Jul 2016

Researchers reveal molecular mechanism of autophagy initiation

Researchers revealed that Atg13 links autophagy initiation factors to each other using a string-like conformation, thereby promoting the association of diverse elements of the autophagy initiation machinery, initiating autophagosome formation through the recruitment of Atg9 vesicles and phosphorylation of various Atg factors.

12 Jul 2016

Cryopreserved human umbilical cord patch shows promise in treating fetal spina bifida

A patch made from cryopreserved human umbilical cord may be a novel method for treating spina bifida in utero, according to researchers at McGovern Medical School at The University of Texas Health Science Center at Houston.

12 Jul 2016

FAU researchers aim to find new ways of detecting cancer micrometastases

What is the likelihood of a patient developing cancer again after having a tumour removed? This is the question that experts in medicine and medical informatics at Friedrich-Alexander-Universität aim to find answers to in a new research project in which they will be researching micrometastases that can form new tumours years after skin cancer, for example, has been treated successfully.

11 Jul 2016

Researchers discover new signaling events that trigger metastasis in ovarian cancer cells

Like pancreatic cancer, cancer of the ovaries is notorious for being discovered at a relatively late stage - after it has spread to other sites in the body. It is not called "the silent killer" for nothing.

11 Jul 2016

Public urinals can generate electricity with help of bacterial metabolism

Pee can be transformed into electricity with the help of bacterial metabolism, thanks to a device created by researchers at the University of the West of England, where Spanish researchers are working.

8 Jul 2016

Mitochondrial stress can trigger tumor-related metabolic shifts, study finds

Cancerous tumors must be fed. Their unregulated growth requires a steady stream of blood flow and nutrients. Thus, one way that researchers have tried to wipe out cancer is to target cells undergoing the metabolic shifts that enable a tumor's rapid growth.

7 Jul 2016

Study demonstrates role of leukocyte activation receptor CD69 in development of psoriasis

Scientists at the Centro de Investigaciones Cardiovasculares Carlos III have defined the key role of an immune-system receptor in the development of psoriasis, suggesting that it could serve as a therapeutic target for the control of this disease.

5 Jul 2016

Researchers uncover sensing mechanism of food poisoning bacteria found in shellfish

UT Southwestern Medical Center researchers have uncovered a mechanism that a type of pathogenic bacteria found in shellfish use to sense when they are in the human gut, where they release toxins that cause food poisoning.

5 Jul 2016

New research holds potential to improve fetal surgery outcomes

University of California, Berkeley engineer Phillip Messersmith is happy to be learning lessons from a lowly mollusk, with the expectation that the knowledge gained will enable him and fellow physicians to prevent deaths among their youngest patients -- those who haven't been born yet.

4 Jul 2016

Membrane News and Research

Researchers find conceivable alternative way to treat Pompe disease

Scientists create new cell-membrane-like material with potential for water purification and drug delivery

Scientists find new way to clear urinary tract infections

Researchers discover novel neuroprotection strategies to slow progression of Parkinson's disease

Study pinpoints how immune abnormalities in retina may lead to macular degeneration

Bad diet can affect immune system prior to weight gain, new research shows

Researchers discover how Zika virus travels from pregnant mother to fetus

Scientists capture atomic level snapshots of how key enzyme modifies signaling proteins

Scientists capture new images of calcium-shuttling molecule linked to aggressive cancers

New, minimally invasive procedure may be effective for patients with FED

Researchers identify new mechanism by which bacteria outsmarts immune system

Researchers reveal molecular mechanism of autophagy initiation

Cryopreserved human umbilical cord patch shows promise in treating fetal spina bifida

FAU researchers aim to find new ways of detecting cancer micrometastases

Researchers discover new signaling events that trigger metastasis in ovarian cancer cells

Public urinals can generate electricity with help of bacterial metabolism

Mitochondrial stress can trigger tumor-related metabolic shifts, study finds

Study demonstrates role of leukocyte activation receptor CD69 in development of psoriasis

Researchers uncover sensing mechanism of food poisoning bacteria found in shellfish

New research holds potential to improve fetal surgery outcomes

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