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Study links OCD improvement to brain activity shift

A recent study from Baylor College of Medicine and Texas Children's Hospital has identified a specific neural activity pattern as a novel biomarker to accurately predict and monitor the clinical status of individuals with obsessive-compulsive disorder (OCD) who have undergone deep brain stimulation (DBS), a rapidly emerging therapeutic approach for severe psychiatric disorders. The study, led by led by Drs. Sameer Sheth and Wayne Goodman along with co-lead authors, Drs. Nicole Provenza, Sandy Reddy, and Anthony Allam, was published in Nature Medicine.

13 Jul 2024

Gene editing silences mutant microRNA, restores hearing in adult mice

Researchers have used gene editing to restore hearing in adult mice with a type of inherited hearing loss. They showed that shutting down a damaged copy of a gene called a microRNA (miRNA) enabled the animals to regain hearing. The approach by a research team supported by the National Institutes of Health (NIH), reported in Science Translational Medicine, may eventually lead to potential treatments for inherited hearing loss in people.

13 Jul 2024

Almirall's Ebglyss recommended by NICE for NHS atopic dermatitis patients

Almirall S.A., a global biopharmaceutical company dedicated to medical dermatology, announced today that the National Institute for Health and Care Excellence (NICE) has recommended Ebglyss (lebrikizumab) for use in moderate to severe Atopic Dermatitis in the NHS England.

13 Jul 2024

Simple measures can help address malnutrition in elderly care

As many as half of all patients admitted to hospital and other healthcare facilities are malnourished. This has serious consequences for the individual in terms of unnecessary suffering, poorer quality of life and mortality.

12 Jul 2024

Technology-assisted therapy for kids and young people is as effective as traditional face-to-face therapy

Using technology to deliver therapy for children and young people is as effective as traditional face-to-face therapy, according to new research.

12 Jul 2024

Study identifies RFC4 as key player in nasopharyngeal carcinoma

Lichuan Wu et al., at Medical College of Guangxi University, China, presented a comprehensive study on the role of replication factor C subunit 4 (RFC4) in nasopharyngeal carcinoma (NPC), a type of epithelial cancer commonly associated with Epstein-Barr virus infection.

12 Jul 2024

Study finds racial and ethnic disparities in postpartum pain medication

Inequities in pain medication treatment received postpartum, after giving birth, were found in a Cedars-Sinai study of 18,000 women. The disparities were observed even among patients reporting the highest pain levels.

12 Jul 2024

How to find a good, well-staffed nursing home

Few people want to go into a nursing home, but doing so can be the right choice if you or a loved one is physically or cognitively disabled or recovering from surgery.

12 Jul 2024

Inulin gel-based oral immunotherapy is effective in suppressing food allergy responses and anaphylactic shock

A novel oral immunotherapy platform that uses formulated inulin gel combined with food allergens to orally deliver dietary antigens.

12 Jul 2024

Cellular immunotherapy offers hope for solid tumors

Early findings from a small clinical trial provide evidence that a new cellular immunotherapy approach may be effective in treating metastatic solid tumors. In the trial, researchers from the National Institutes of Health (NIH) genetically engineered normal white blood cells, known as lymphocytes, from each patient to produce receptors that recognize and attack their specific cancer cells.

12 Jul 2024

Menstrual cramps can be more severe and last longer during anovulatory cycles

According to current understanding, menstrual cramps only happen in cycles in which an egg is released, or an ovulatory cycle. But new research from the University of British Columbia (UBC) is challenging this notion.

11 Jul 2024

How lipoproteins shape your metabolic health

Study provides a comprehensive review of the lipoprotein pathway and its impact on healthy metabolism, highlighting the roles of HDL, LDL, and other lipoproteins in cardiovascular health and disease.

11 Jul 2024

deCODE genetics study highlights potential drug targets for autoimmune thyroid disease

Scientists at deCODE genetics, a subsidiary of Amgen, have published a study in Nature Communications, comparing over 110 thousand patients with autoimmune thyroid disease (AITD) from Iceland, Finland, UK and USA with 1,1 million controls.

11 Jul 2024

Researchers discover a new mechanism of resistance to KRAS inhibitors in pancreas cancer

Mutations in the KRAS gene are the primary driver of pancreatic cancer. A new class of drugs known as KRAS inhibitors is showing initial promise in clinical trials, but many tumors quickly develop resistance to the treatment.

11 Jul 2024

CD22-targeted CAR-T therapy shows promising results in relapsed large B-cell lymphoma

CAR-T cell therapy, which targets a specific protein on the surface of cancer cells, causes tumors to shrink or disappear in about half of patients with large B-cell lymphoma who haven't experienced improvement with chemotherapy treatments.

11 Jul 2024

Machine-learning model can predict survival of dialysis patients on Continuous Renal Replacement Therapy

A UCLA-led team has developed a machine-learning model that can predict with a high degree of accuracy the short-term survival of dialysis patients on Continuous Renal Replacement Therapy (CRRT).

11 Jul 2024

Researchers identify molecular processes crucial for the maturation of Group 2 innate lymphoid cells

Scientists have discovered a novel mechanism of ILC2 immune cell development which may be involved in exacerbating allergic diseases.

11 Jul 2024

‘A bottomless pit’: How out-of-pocket TMJ costs drive patients into debt

Over three decades of relentless pain, Jonna Tallant has tried about every TMJ treatment: mouthguards, six sets of braces, dental crowns and appliances, drugs, physical therapy, Botox, massage, acupuncture, chiropractic care, and surgery.

11 Jul 2024

Innovative aiTBS therapy shortens treatment duration for bipolar disorder

A potential new treatment for bipolar disorder (BP) that significantly shortens treatment time has emerged, following a randomized clinical trial using accelerated intermittent theta burst stimulation (aiTBS).

11 Jul 2024

LSVT LOUD outperforms NHS speech and language therapy for people with Parkinson's disease

An intensive voice treatment developed in the USA and known as the Lee Silverman voice treatment (LSVT LOUD) is more effective than conventional NHS speech and language therapy or no therapy for people with Parkinson's disease, finds a trial published in The BMJ today.

11 Jul 2024

Therapy News and Research

Study links OCD improvement to brain activity shift

Gene editing silences mutant microRNA, restores hearing in adult mice

Almirall's Ebglyss recommended by NICE for NHS atopic dermatitis patients

Simple measures can help address malnutrition in elderly care

Technology-assisted therapy for kids and young people is as effective as traditional face-to-face therapy

Study identifies RFC4 as key player in nasopharyngeal carcinoma

Study finds racial and ethnic disparities in postpartum pain medication

How to find a good, well-staffed nursing home

Inulin gel-based oral immunotherapy is effective in suppressing food allergy responses and anaphylactic shock

Cellular immunotherapy offers hope for solid tumors

Menstrual cramps can be more severe and last longer during anovulatory cycles

How lipoproteins shape your metabolic health

deCODE genetics study highlights potential drug targets for autoimmune thyroid disease

Researchers discover a new mechanism of resistance to KRAS inhibitors in pancreas cancer

CD22-targeted CAR-T therapy shows promising results in relapsed large B-cell lymphoma

Machine-learning model can predict survival of dialysis patients on Continuous Renal Replacement Therapy

Researchers identify molecular processes crucial for the maturation of Group 2 innate lymphoid cells

‘A bottomless pit’: How out-of-pocket TMJ costs drive patients into debt

Innovative aiTBS therapy shortens treatment duration for bipolar disorder

LSVT LOUD outperforms NHS speech and language therapy for people with Parkinson's disease

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