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Discovery of unique approach for delivering drugs to the brain - potential for Alzheimer's and stroke

Saint Louis University researchers have identified a novel way of getting a potential treatment for Alzheimer's disease and stroke into the brain where it can do its work.

12 Nov 2008

Female testosterone therapy no magic bullet for sexual dysfunction

Testosterone therapy may not be the magic bullet women with low libidos are hoping for, according to seasoned sex therapist Domeena Renshaw, MD.

12 Nov 2008

Regularly exercise good for heart failure patients

Heart failure patients who regularly exercise fare better and feel better about their lives than do similar patients who do not work out on a regular basis, say researchers at Duke University Medical Center.

12 Nov 2008

Adalimumab therapy may reduce health-care costs for Crohn's disease patients

Inflammatory bowel disease (IBD) is a term that refers to both ulcerative colitis (UC) and Crohn's disease (CD).

12 Nov 2008

Promising clinical trial for patients with obsessive-compulsive disorder

Obsessive-compulsive disorder (OCD) affects 2% of the population and is considered a psychiatric disorder. It is the number four psychiatric pathology in terms of frequency following phobias, disorders relating to alcohol and drugs, and depression.

12 Nov 2008

Scientists crack the code to tamoxifen resistance

CANCER RESEARCH UK scientists have discovered the molecular basis for tamoxifen response in breast cancer cells - and the reason why some women can develop resistance to the treatment, according to a study published in Nature today (Wednesday).

12 Nov 2008

Breakthrough in rheumatoid arthritis research

Rheumatoid arthritis is a painful, inflammatory type of arthritis that occurs when the body's immune system attacks itself.

12 Nov 2008

Dental pulp stem cells show promise for use in cell therapy

Researchers at the Yerkes National Primate Research Center, Emory University, have discovered dental pulp stem cells can stimulate growth and generation of several types of neural cells.

12 Nov 2008

U.S. patents granted to Virginia Tech for targets and methods to develop new drugs for malaria

Virginia Tech Intellectual Properties (VTIP) announces that the US Patent and Trademark Office has granted a patent for targets and methods to develop new drugs for malaria.

11 Nov 2008

Catheter ablation works better than drugs for heart rhythm disorder

Treating a common heart rhythm disorder by burning heart tissue with a catheter works dramatically better than drug treatments, a major international study has found.

11 Nov 2008

Sex hormones may affect atherosclerosis

Naturally produced sex hormones may influence the risk and progression of atherosclerosis, or hardening of the arteries, Johns Hopkins researchers report in a recent study.

11 Nov 2008

Cell-coated stent as effective as drug-coated ones

A stent that entices artery-lining cells to coat it works as well or better than drug-eluting stents in keeping arteries open in coronary heart disease patients, according to two research studies presented at the American Heart Association's Scientific Sessions 2008.

11 Nov 2008

An ideal therapy for peptic ulcer disease

Since the discovery of the etiological role of Helicobacter pylori (H pylori) in peptic ulcer disease, its eradication became the main objective of therapy, and several treatment regimens were developed.

11 Nov 2008

Medicine, math and engineering combine to reveal how sepsis and less severe infections occur

It's a leading cause of death, but no one knows for sure how and why it happens. It's a major source of health care costs, adding days or weeks to the hospital stays and lost work time of millions of people. But no one fully understands how best to fight it.

11 Nov 2008

Large trial on low-dose aspirin in diabetics

Type 2 diabetics treated with low-dose aspirin did not have a significantly lower incidence of atherosclerotic events than those who received placebo in this primary prevention trial of low-dose aspirin, according to research presented at the American Heart Association's Scientific Sessions 2008. However, sub-group analyses showed a significant reduction with aspirin in both atherosclerotic events in those over 65 years of age, and a reduction in cerebrocardiovascular deaths.

11 Nov 2008

Folic acid does not offer any cardiovascular benefits

Folic acid is safe - but it lacks any cardiovascular benefits - according to researchers presenting at the American Heart Association's Scientific Sessions 2008. The results from the Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine (SEARCH), a 12,064-person, randomized study, were presented as a late-breaking clinical trial.

11 Nov 2008

New blood test identifies sickest heart failure patients in ER

A new blood test identifies the sickest heart failure patients better than tests now used in emergency departments, researchers reported at the American Heart Association's Scientific Sessions 2008. Results of the Mid-Regional pro-Adrenomedullin (proADM) versus BNP and NTproBNP as Prognosticator in Heart Failure Patients: Results of the BACH Multinational Trial were presented as a late-breaking clinical trial.

11 Nov 2008

Rivaroxaban shows promise in patients with acute coronary syndrome

Researchers reported on a study of a new oral anti-clotting agent - rivaroxaban - designed to identify doses that would be safe to test in subsequent Phase III efficacy and safety trials. The results of ATLAS ACS-TIMI 46 were presented as a late-breaking clinical trial at the American Heart Association's Scientific Sessions 2008.

11 Nov 2008

Exercise training safe in heart failure patients - offer clinical benefit

Exercise training is safe in heart failure patients, does not significantly reduce hospitalization or death, but is associated with several improved clinical outcomes, even in those already receiving optimal medical care, researchers reported at the American Heart Association's Scientific Sessions 2008. The Heart Failure and A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION) was presented as a late-breaking clinical trial.

11 Nov 2008

New report shows high Clostridium difficile infection rates in U.S. hospitals

Consumers Union called on hospitals today to take more aggressive steps to protect patients from Clostridium difficile (C.-diff.) infections in light of a new report showing that they are much more common than previous estimates had indicated. As the rate of hospital acquired C.-diff. infections has jumped in recent years, an increasing number of patients have developed antibiotic-resistant strains of the infection that are more difficult to treat and more deadly.

11 Nov 2008